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Activation of MYO1G by lncRNA MNX1-AS1 Drives the Progression in Lung Cancer.
Lv D, Wang Y, Li S, Shao X, Jin Q. Lv D, et al. Mol Biotechnol. 2023 Jan;65(1):72-83. doi: 10.1007/s12033-022-00531-y. Epub 2022 Jul 11. Mol Biotechnol. 2023. PMID: 35819746
Lung cancer represents the most prevalent cancer worldwide and causes the death of many patients. ...Finally, MNX1-AS1 suppression significantly repressed the growth of xenografts in vivo. Our study highlights the importance of the MNX1-AS1/POU2F2/MYO1G axis …
Lung cancer represents the most prevalent cancer worldwide and causes the death of many patients. ...Finally, MNX1-AS1 suppres …
miR-3200 accelerates the growth of liver cancer cells by enhancing Rab7A.
Song S, Xie S, Liu X, Li S, Wang L, Jiang X, Lu D. Song S, et al. Noncoding RNA Res. 2023 Oct 10;8(4):675-685. doi: 10.1016/j.ncrna.2023.10.005. eCollection 2023 Dec. Noncoding RNA Res. 2023. PMID: 37860266 Free PMC article.
In this study, we clearly demonstrate that miR-3200 accelerates the growth of liver cancer cells in vivo and in vitro. Obviously, these findings are noteworthy that miR-3200 affects the transcriptional regulation for several genes, including DSP,BABAM2, Rab7A,SQSTM1,PRKAG2 …
In this study, we clearly demonstrate that miR-3200 accelerates the growth of liver cancer cells in vivo and in vitro. Obviously, the …
High expression of Myosin 1g in pediatric acute lymphoblastic leukemia.
Estrada-Abreo LA, Rodríguez-Cruz L, Garfias-Gómez Y, Araujo-Cardenas JE, Antonio-Andrés G, Salgado-Aguayo AR, Orozco-Ruiz D, Torres-Nava JR, Díaz-Valencia JD, Huerta-Yépez S, Patiño-López G. Estrada-Abreo LA, et al. Oncotarget. 2021 Sep 14;12(19):1937-1945. doi: 10.18632/oncotarget.28055. eCollection 2021 Sep 14. Oncotarget. 2021. PMID: 34548909 Free PMC article.
Class I myosins are molecular motors involved in membrane tension, endocytosis, phagocytosis and cell migration and recently they have been shown important for development and aggressiveness of diverse cancer types, however Myo1g an hematopoietic specific myosin has …
Class I myosins are molecular motors involved in membrane tension, endocytosis, phagocytosis and cell migration and recently they have been …
Detection of Myosin 1g Overexpression in Pediatric Leukemia by Novel Monoclonal Antibodies.
Rodríguez-Téllez RI, Ribas-Aparicio RM, Patiño-López G. Rodríguez-Téllez RI, et al. Int J Mol Sci. 2022 Apr 1;23(7):3912. doi: 10.3390/ijms23073912. Int J Mol Sci. 2022. PMID: 35409272 Free PMC article.
Despite the importance of Myo1g in distinct functions, there is currently no monoclonal antibody (mAb) against Myo1g. mAbs are helpful tools for the detection of specific antigens in tumor cells and other tissues. ...Using hybridoma technology, we generated a panel …
Despite the importance of Myo1g in distinct functions, there is currently no monoclonal antibody (mAb) against Myo1g. mAbs are …
Hypermethylation of SCAND3 and Myo1g Gene Are Potential Diagnostic Biomarkers for Hepatocellular Carcinoma.
Xu F, Zhang L, Xu Y, Song D, He W, Ji X, Shao J. Xu F, et al. Cancers (Basel). 2020 Aug 18;12(8):2332. doi: 10.3390/cancers12082332. Cancers (Basel). 2020. PMID: 32824823 Free PMC article.
The values of serum SCAND3, Myo1g, and SCAND3 + Myo1g methylation with respect to facilitating the detection, and early detection of HCC were better than for alpha-fetoprotein (AFP) alone. Furthermore, when we combined SCAND3 + Myo1g with AFP, a high sensitiv …
The values of serum SCAND3, Myo1g, and SCAND3 + Myo1g methylation with respect to facilitating the detection, and early detect …
In-Depth Proteomics Analysis to Identify Biomarkers of Papillary Thyroid Cancer Patients Older Than 45 Years with Different Degrees of Lymph Node Metastases.
Zhan S, Wang T, Wang M, Li J, Ge W. Zhan S, et al. Proteomics Clin Appl. 2019 Sep;13(5):e1900030. doi: 10.1002/prca.201900030. Epub 2019 Jun 7. Proteomics Clin Appl. 2019. PMID: 31148369
The expression patterns of six DEPs (LAMC2, LAMB3, ATP5A1, MYO1G, S100A4, and FAS) are confirmed by the Cancer Genome Atlas dataset. ...CONCLUSIONS AND CLINICAL RELEVANCE: LAMC2 and MYO1G are identified as potential candidate biomarkers for the prediction of …
The expression patterns of six DEPs (LAMC2, LAMB3, ATP5A1, MYO1G, S100A4, and FAS) are confirmed by the Cancer Genome Atlas da …
Identification of cytoskeleton-associated proteins essential for lysosomal stability and survival of human cancer cells.
Groth-Pedersen L, Aits S, Corcelle-Termeau E, Petersen NH, Nylandsted J, Jäättelä M. Groth-Pedersen L, et al. PLoS One. 2012;7(10):e45381. doi: 10.1371/journal.pone.0045381. Epub 2012 Oct 11. PLoS One. 2012. PMID: 23071517 Free PMC article.
To identify specific trafficking-related proteins that control cell survival and lysosomal stability, we screened a molecular motor siRNA library in human MCF7 breast cancer cells. SiRNAs targeting four kinesins (KIF11/Eg5, KIF20A, KIF21A, KIF25), myosin 1G (MYO1G), …
To identify specific trafficking-related proteins that control cell survival and lysosomal stability, we screened a molecular motor siRNA li …
Class I Myosins, molecular motors involved in cell migration and cancer.
Diaz-Valencia JD, Estrada-Abreo LA, Rodríguez-Cruz L, Salgado-Aguayo AR, Patiño-López G. Diaz-Valencia JD, et al. Cell Adh Migr. 2022 Dec;16(1):1-12. doi: 10.1080/19336918.2021.2020705. Cell Adh Migr. 2022. PMID: 34974807 Free PMC article.
Recently has been reported that changes in myosin expression have an impact on the migration of cancer cells, the formation of infiltrates and metastasis. We propose that class I myosins might be potential markers for future diagnostic, prognostic or even as therapeutic ta …
Recently has been reported that changes in myosin expression have an impact on the migration of cancer cells, the formation of infilt …
Detection of rare antigen-presenting cells through T cell-intrinsic meandering motility, mediated by Myo1g.
Gérard A, Patino-Lopez G, Beemiller P, Nambiar R, Ben-Aissa K, Liu Y, Totah FJ, Tyska MJ, Shaw S, Krummel MF. Gérard A, et al. Cell. 2014 Jul 31;158(3):492-505. doi: 10.1016/j.cell.2014.05.044. Cell. 2014. PMID: 25083865 Free PMC article.
T cell motility in tissues resembles a random or Levy walk and is regulated in part by external factors including chemokines and lymph-node topology, but motility parameters such as speed and propensity to turn may also be cell intrinsic. Here we found that the unconventional myo …
T cell motility in tissues resembles a random or Levy walk and is regulated in part by external factors including chemokines and lymph-node …
Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells.
Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M. Carli ALE, et al. Proteomics. 2021 Jul;21(13-14):e2000098. doi: 10.1002/pmic.202000098. Epub 2021 May 28. Proteomics. 2021. PMID: 33991177
Doublecortin-like kinase 1 (DCLK1) is a putative cancer stem cell marker, a promising diagnostic and prognostic maker for malignant tumors and a proposed driver gene for gastric cancer (GC). DCLK1 overexpression in a majority of solid cancers correlates with …
Doublecortin-like kinase 1 (DCLK1) is a putative cancer stem cell marker, a promising diagnostic and prognostic maker for malignant t …
25 results