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Structural insights into RNA processing by the human RISC-loading complex.
Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, Doudna JA, Nogales E. Wang HW, et al. Among authors: ma e. Nat Struct Mol Biol. 2009 Nov;16(11):1148-53. doi: 10.1038/nsmb.1673. Epub 2009 Oct 11. Nat Struct Mol Biol. 2009. PMID: 19820710 Free PMC article.
Substrate-specific structural rearrangements of human Dicer.
Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW. Taylor DW, et al. Among authors: ma e. Nat Struct Mol Biol. 2013 Jun;20(6):662-70. doi: 10.1038/nsmb.2564. Epub 2013 Apr 28. Nat Struct Mol Biol. 2013. PMID: 23624860 Free PMC article.
In vitro reconstitution of the human RISC-loading complex.
MacRae IJ, Ma E, Zhou M, Robinson CV, Doudna JA. MacRae IJ, et al. Among authors: ma e. Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):512-7. doi: 10.1073/pnas.0710869105. Epub 2008 Jan 4. Proc Natl Acad Sci U S A. 2008. PMID: 18178619 Free PMC article.
CasX enzymes comprise a distinct family of RNA-guided genome editors.
Liu JJ, Orlova N, Oakes BL, Ma E, Spinner HB, Baney KLM, Chuck J, Tan D, Knott GJ, Harrington LB, Al-Shayeb B, Wagner A, Brötzmann J, Staahl BT, Taylor KL, Desmarais J, Nogales E, Doudna JA. Liu JJ, et al. Among authors: ma e. Nature. 2019 Feb;566(7743):218-223. doi: 10.1038/s41586-019-0908-x. Epub 2019 Feb 4. Nature. 2019. PMID: 30718774 Free PMC article.
A thermostable Cas9 with increased lifetime in human plasma.
Harrington LB, Paez-Espino D, Staahl BT, Chen JS, Ma E, Kyrpides NC, Doudna JA. Harrington LB, et al. Among authors: ma e. Nat Commun. 2017 Nov 10;8(1):1424. doi: 10.1038/s41467-017-01408-4. Nat Commun. 2017. PMID: 29127284 Free PMC article.
1,394 results