Mackay S - Search Results

1

Multiomics and spatial mapping characterizes human CD8⁺ T cell states in cancer.

Naulaerts S, Datsi A, Borras DM, Antoranz Martinez A, Messiaen J, Vanmeerbeek I, Sprooten J, Laureano RS, Govaerts J, Panovska D, Derweduwe M, Sabel MC, Rapp M, Ni W, Mackay S, Van Herck Y, Gelens L, Venken T, More S, Bechter O, Bergers G, Liston A, De Vleeschouwer S, Van Den Eynde BJ, Lambrechts D, Verfaillie M, Bosisio F, Tejpar S, Borst J, Sorg RV, De Smet F, Garg AD. Naulaerts S, et al. Among authors: mackay s. Sci Transl Med. 2023 Apr 12;15(691):eadd1016. doi: 10.1126/scitranslmed.add1016. Epub 2023 Apr 12. Sci Transl Med. 2023. PMID: 37043555

2

Applying single-cell highly multiplexed secretome proteomics to characterize immunotherapeutic products and predict clinical responses.

Ni W, Han EX, Cyr M, Mackay S, Zhou J. Ni W, et al. Among authors: mackay s. Proteomics. 2023 Jul;23(13-14):e2200242. doi: 10.1002/pmic.202200242. Epub 2023 Feb 25. Proteomics. 2023. PMID: 36786585 Review.

3

Camel nanobody-based B7-H3 CAR-T cells show high efficacy against large solid tumours.

Li D, Wang R, Liang T, Ren H, Park C, Tai CH, Ni W, Zhou J, Mackay S, Edmondson E, Khan J, Croix BS, Ho M. Li D, et al. Among authors: mackay s. Nat Commun. 2023 Sep 22;14(1):5920. doi: 10.1038/s41467-023-41631-w. Nat Commun. 2023. PMID: 37739951 Free PMC article.

4

The Potential Role of Cytotoxic Immune Effectors in Induction, Progression and Pathogenesis of Amyotrophic Lateral Sclerosis (ALS).

Kaur K, Chen PC, Ko MW, Mei A, Chovatiya N, Huerta-Yepez S, Ni W, Mackay S, Zhou J, Maharaj D, Malarkannan S, Jewett A. Kaur K, et al. Among authors: mackay s. Cells. 2022 Oct 31;11(21):3431. doi: 10.3390/cells11213431. Cells. 2022. PMID: 36359827 Free PMC article.

5

The IgG4 hinge with CD28 transmembrane domain improves V_HH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer.

Li N, Quan A, Li D, Pan J, Ren H, Hoeltzel G, de Val N, Ashworth D, Ni W, Zhou J, Mackay S, Hewitt SM, Cachau R, Ho M. Li N, et al. Among authors: mackay s. Nat Commun. 2023 Apr 8;14(1):1986. doi: 10.1038/s41467-023-37616-4. Nat Commun. 2023. PMID: 37031249 Free PMC article.

6

CD8+ T-cell mediated anti-malaria protection induced by malaria vaccines; assessment of hepatic CD8+ T cells by SCBC assay.

Zhou J, Kaiser A, Ng C, Karcher R, McConnell T, Paczkowski P, Fernandez C, Zhang M, Mackay S, Tsuji M. Zhou J, et al. Among authors: mackay s. Hum Vaccin Immunother. 2017 Jul 3;13(7):1625-1629. doi: 10.1080/21645515.2017.1304333. Hum Vaccin Immunother. 2017. PMID: 28362549 Free PMC article.

7

Targeted Co-delivery of Tumor Antigen and α-Galactosylceramide to CD141⁺ Dendritic Cells Induces a Potent Tumor Antigen-Specific Human CD8⁺ T Cell Response in Human Immune System Mice.

Huang J, Zhou J, Ghinnagow R, Seki T, Iketani S, Soulard D, Paczkowski P, Tsuji Y, MacKay S, Cruz LJ, Trottein F, Tsuji M. Huang J, et al. Among authors: mackay s. Front Immunol. 2020 Aug 18;11:2043. doi: 10.3389/fimmu.2020.02043. eCollection 2020. Front Immunol. 2020. PMID: 32973811 Free PMC article.

8

Single-cell polyfunctional proteomics of CD4 cells from patients with AML predicts responses to anti-PD-1-based therapy.

Abbas HA, Alaniz Z, Mackay S, Cyr M, Zhou J, Issa GC, Alfayez M, Matthews J, Kornblau SM, Jabbour E, Garcia-Manero G, Konopleva M, Andreeff M, Daver N. Abbas HA, et al. Among authors: mackay s. Blood Adv. 2021 Nov 23;5(22):4569-4574. doi: 10.1182/bloodadvances.2021004583. Blood Adv. 2021. PMID: 34555853 Free PMC article.

9

Single-Cell Multiplexed Proteomics on the IsoLight Resolves Cellular Functional Heterogeneity to Reveal Clinical Responses of Cancer Patients to Immunotherapies.

Liu D, Paczkowski P, Mackay S, Ng C, Zhou J. Liu D, et al. Among authors: mackay s. Methods Mol Biol. 2020;2055:413-431. doi: 10.1007/978-1-4939-9773-2_19. Methods Mol Biol. 2020. PMID: 31502163

10

Advanced Cell Mapping Visualizations for Single Cell Functional Proteomics Enabling Patient Stratification.

Bowman N, Liu D, Paczkowski P, Chen J, Rossi J, Mackay S, Bot A, Zhou J. Bowman N, et al. Among authors: mackay s. Proteomics. 2020 Jul;20(13):e1900270. doi: 10.1002/pmic.201900270. Proteomics. 2020. PMID: 32108428

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