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1991 1
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2000 27
2001 30
2002 23
2003 32
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763 results

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Page 1
Immunological and functional aspects of MAGEA3 cancer/testis antigen.
Das B, Senapati S. Das B, et al. Adv Protein Chem Struct Biol. 2021;125:121-147. doi: 10.1016/bs.apcsb.2020.08.001. Epub 2020 Oct 1. Adv Protein Chem Struct Biol. 2021. PMID: 33931137 Review.
Among CT antigens MAGEA family is reported to have 12 members (MAGEA1 to MAGEA12). The current review highlights the studies on MAGEA3 which is a CT antigen and reported in almost all types of cancer. MAGEA3 is well tried for cancer immunotherapy. Recent advances on …
Among CT antigens MAGEA family is reported to have 12 members (MAGEA1 to MAGEA12). The current review highlights the studies on MAGEA3 …
MAGEA3 promotes proliferation and suppresses apoptosis in cervical cancer cells by inhibiting the KAP1/p53 signaling pathway.
Gao X, Li Q, Chen G, He H, Ma Y. Gao X, et al. Am J Transl Res. 2020 Jul 15;12(7):3596-3612. eCollection 2020. Am J Transl Res. 2020. PMID: 32774721 Free PMC article.
Accumulating evidence indicates that MAGEA3 plays a vital role in the pathogenesis and development of various cancers. However, the underlying mechanisms behind the tumor-promoting effect of MAGEA3 remain unclear, particularly in cervical cancer (CC). The present st …
Accumulating evidence indicates that MAGEA3 plays a vital role in the pathogenesis and development of various cancers. However, the u …
LINC01234/MicroRNA-31-5p/MAGEA3 Axis Mediates the Proliferation and Chemoresistance of Hepatocellular Carcinoma Cells.
Chen Y, Zhao H, Li H, Feng X, Tang H, Qiu C, Zhang J, Fu B. Chen Y, et al. Mol Ther Nucleic Acids. 2020 Mar 6;19:168-178. doi: 10.1016/j.omtn.2019.10.035. Epub 2019 Nov 13. Mol Ther Nucleic Acids. 2020. PMID: 31838274 Free PMC article. Retracted.
We investigated the mechanism of how MAGEA3 and LINC01234 influenced HCC cellular functions and cisplatin resistance. ...RNA pull-down and RIP assays identified the binding of LINC01234 and MAGEA3 to microRNA-31-5p (miR-31-5p). LINC01234 could restore MAGEA3 …
We investigated the mechanism of how MAGEA3 and LINC01234 influenced HCC cellular functions and cisplatin resistance. ...RNA pull-dow …
Functional and mechanistic studies reveal MAGEA3 as a pro-survival factor in pancreatic cancer cells.
Das B, Senapati S. Das B, et al. J Exp Clin Cancer Res. 2019 Jul 8;38(1):294. doi: 10.1186/s13046-019-1272-2. J Exp Clin Cancer Res. 2019. PMID: 31287009 Free PMC article.
MAGEA3 was also depleted in certain MAGEA3 positive PCCs by siRNA or shRNA. ...However, depletion of MAGEA3 in MAGEA3 positive cells resulted in reduced cell proliferation and increased apoptosis upon growth factor deprivation and also in response to c …
MAGEA3 was also depleted in certain MAGEA3 positive PCCs by siRNA or shRNA. ...However, depletion of MAGEA3 in MAGEA …
Comprehensive Analysis to Identify MAGEA3 Expression Correlated With Immune Infiltrates and Lymph Node Metastasis in Gastric Cancer.
Jin J, Tu J, Ren J, Cai Y, Chen W, Zhang L, Zhang Q, Zhu G. Jin J, et al. Front Oncol. 2021 Dec 14;11:784925. doi: 10.3389/fonc.2021.784925. eCollection 2021. Front Oncol. 2021. PMID: 34970496 Free PMC article.
We evaluate the potential role of MAGEA3 in GC through the TCGA database. The result revealed that MAGEA3 is upregulated in GC and linked to poor OS and lymph node metastasis. ...In addition, GSEA-identified MAGEA3 is involved in the immune regulation of GC. …
We evaluate the potential role of MAGEA3 in GC through the TCGA database. The result revealed that MAGEA3 is upregulated in GC …
Cancer/testis Antigen MAGEA3 Interacts with STAT1 and Remodels the Tumor Microenvironment.
Wang Y, Song X, Zheng Y, Liu Z, Li Y, Qian X, Pang X, Zhang Y, Yin Y. Wang Y, et al. Int J Med Sci. 2018 Nov 22;15(14):1702-1712. doi: 10.7150/ijms.27643. eCollection 2018. Int J Med Sci. 2018. PMID: 30588194 Free PMC article.
We show that pY-STAT1 is significantly up-regulated when MAGEA3 is silenced by MAGEA3-specific siRNA. RNA sequencing analysis identified 274 STAT1-related genes to be significantly altered in expression level in MAGEA3 knockdown cells. ...Our findings reveal …
We show that pY-STAT1 is significantly up-regulated when MAGEA3 is silenced by MAGEA3-specific siRNA. RNA sequencing analysis …
ODF4, MAGEA3, and MAGEB4: Potential Biomarkers in Patients with Transitional Cell Carcinoma.
Afsharpad M, Nowroozi MR, Ayati M, Saffari M, Nemati S, Mohebbi E, Nekoohesh L, Zendehdel K, Modarressi MH. Afsharpad M, et al. Iran Biomed J. 2018 May 1;22(3):160-70. doi: 10.22034/ibj.22.3.160. Epub 2017 Sep 3. Iran Biomed J. 2018. PMID: 28865418 Free PMC article.
Combining ODF4, MAGEA3, and MAGEAB4 RT-PCR offered a relatively higher sensitivity (83.6%). CONCLUSION: RT-PCR with ODF4, MAGEA3, and MAGEAB4 on urinary exfoliated cells could provide clinicians with a promising method to improve TCC diagnosis, especially in the cas …
Combining ODF4, MAGEA3, and MAGEAB4 RT-PCR offered a relatively higher sensitivity (83.6%). CONCLUSION: RT-PCR with ODF4, MAGEA3 …
miR-1273g silences MAGEA3/6 to inhibit human colorectal cancer cell growth via activation of AMPK signaling.
Wu F, Liu F, Dong L, Yang H, He X, Li L, Zhao L, Jin S, Li G. Wu F, et al. Cancer Lett. 2018 Oct 28;435:1-9. doi: 10.1016/j.canlet.2018.07.031. Epub 2018 Jul 26. Cancer Lett. 2018. PMID: 30056111
Here, using a bioinformatic approach, we identified a microRNA, miR-1273g-3p, that is predicted to target the 3' untranslated region (UTR) of MAGEA3/6. Analyzing miR-1273g-3p expression in human colon cancer tissues, we found a reduction in miR-1273g-3p expression correlat …
Here, using a bioinformatic approach, we identified a microRNA, miR-1273g-3p, that is predicted to target the 3' untranslated region (UTR) o …
763 results