Maglich JM - Search Results

1

Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists.

Yates CM, Brown PJ, Stewart EL, Patten C, Austin RJ, Holt JA, Maglich JM, Angell DC, Sasse RZ, Taylor SJ, Uings IJ, Trump RP. Yates CM, et al. Among authors: maglich jm. J Med Chem. 2010 Jun 10;53(11):4531-44. doi: 10.1021/jm100447c. J Med Chem. 2010. PMID: 20469868

2

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. Maglich JM, et al. J Biol Chem. 2003 May 9;278(19):17277-83. doi: 10.1074/jbc.M300138200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12611900 Free article.

3

The relative activity of "function sparing" HIV-1 entry inhibitors on viral entry and CCR5 internalization: is allosteric functional selectivity a valuable therapeutic property?

Muniz-Medina VM, Jones S, Maglich JM, Galardi C, Hollingsworth RE, Kazmierski WM, Ferris RG, Edelstein MP, Chiswell KE, Kenakin TP. Muniz-Medina VM, et al. Among authors: maglich jm. Mol Pharmacol. 2009 Mar;75(3):490-501. doi: 10.1124/mol.108.052555. Epub 2008 Dec 8. Mol Pharmacol. 2009. PMID: 19064629

4

Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages.

Whitney KD, Watson MA, Goodwin B, Galardi CM, Maglich JM, Wilson JG, Willson TM, Collins JL, Kliewer SA. Whitney KD, et al. Among authors: maglich jm. J Biol Chem. 2001 Nov 23;276(47):43509-15. doi: 10.1074/jbc.M106155200. Epub 2001 Aug 23. J Biol Chem. 2001. PMID: 11546778 Free article.

5

The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction.

Maglich JM, Watson J, McMillen PJ, Goodwin B, Willson TM, Moore JT. Maglich JM, et al. J Biol Chem. 2004 May 7;279(19):19832-8. doi: 10.1074/jbc.M313601200. Epub 2004 Mar 5. J Biol Chem. 2004. PMID: 15004031 Free article.

6

Beyond the human genome: examples of nuclear receptor analysis in model organisms and potential for drug discovery.

Maglich JM, Sluder AE, Willson TM, Moore JT. Maglich JM, et al. Am J Pharmacogenomics. 2003;3(5):345-53. doi: 10.2165/00129785-200303050-00005. Am J Pharmacogenomics. 2003. PMID: 14575522 Review.

7

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.

Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT. Moore LB, et al. Among authors: maglich jm. Mol Endocrinol. 2002 May;16(5):977-86. doi: 10.1210/mend.16.5.0828. Mol Endocrinol. 2002. PMID: 11981033

8

The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress.

Maglich JM, Lobe DC, Moore JT. Maglich JM, et al. J Lipid Res. 2009 Mar;50(3):439-445. doi: 10.1194/jlr.M800226-JLR200. Epub 2008 Oct 21. J Lipid Res. 2009. PMID: 18941143 Free article.

9

2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin.

Watkins RE, Maglich JM, Moore LB, Wisely GB, Noble SM, Davis-Searles PR, Lambert MH, Kliewer SA, Redinbo MR. Watkins RE, et al. Among authors: maglich jm. Biochemistry. 2003 Feb 18;42(6):1430-8. doi: 10.1021/bi0268753. Biochemistry. 2003. PMID: 12578355

10

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.

Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA. Maglich JM, et al. Mol Pharmacol. 2002 Sep;62(3):638-46. doi: 10.1124/mol.62.3.638. Mol Pharmacol. 2002. PMID: 12181440

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