Mahajan P - Search Results

1

Discovery of novel pyrazolopyrimidinone analogs as potent inhibitors of phosphodiesterase type-5.

Sawant SD, Lakshma Reddy G, Dar MI, Srinivas M, Gupta G, Sahu PK, Mahajan P, Nargotra A, Singh S, Sharma SC, Tikoo M, Singh G, Vishwakarma RA, Syed SH. Sawant SD, et al. Among authors: mahajan p. Bioorg Med Chem. 2015 May 1;23(9):2121-8. doi: 10.1016/j.bmc.2015.03.005. Epub 2015 Mar 9. Bioorg Med Chem. 2015. PMID: 25801159

2

Synthesis of 5-substituted-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one analogs and their biological evaluation as anticancer agents: mTOR inhibitors.

Reddy GL, Guru SK, Srinivas M, Pathania AS, Mahajan P, Nargotra A, Bhushan S, Vishwakarma RA, Sawant SD. Reddy GL, et al. Among authors: mahajan p. Eur J Med Chem. 2014 Jun 10;80:201-8. doi: 10.1016/j.ejmech.2014.04.051. Epub 2014 Apr 18. Eur J Med Chem. 2014. PMID: 24780597

3

4-(N-Phenyl-N'-substituted benzenesulfonyl)-6-(4-hydroxyphenyl)quinolines as inhibitors of mammalian target of rapamycin.

Venkateswarlu V, Pathania AS, Aravinda Kumar KA, Mahajan P, Nargotra A, Vishwakarma RA, Malik FA, Sawant SD. Venkateswarlu V, et al. Among authors: mahajan p. Bioorg Med Chem. 2015 Aug 1;23(15):4237-4247. doi: 10.1016/j.bmc.2015.06.046. Epub 2015 Jun 26. Bioorg Med Chem. 2015. PMID: 26162498

4

Design of Novel 3-Pyrimidinylazaindole CDK2/9 Inhibitors with Potent In Vitro and In Vivo Antitumor Efficacy in a Triple-Negative Breast Cancer Model.

Singh U, Chashoo G, Khan SU, Mahajan P, Nargotra A, Mahajan G, Singh A, Sharma A, Mintoo MJ, Guru SK, Aruri H, Thatikonda T, Sahu P, Chibber P, Kumar V, Mir SA, Bharate SS, Madishetti S, Nandi U, Singh G, Mondhe DM, Bhushan S, Malik F, Mignani S, Vishwakarma RA, Singh PP. Singh U, et al. Among authors: mahajan g, mahajan p. J Med Chem. 2017 Dec 14;60(23):9470-9489. doi: 10.1021/acs.jmedchem.7b00663. Epub 2017 Dec 5. J Med Chem. 2017. PMID: 29144137

5

Design and synthesis of 1,4-substituted 1H-1,2,3-triazolo-quinazolin-4(3H)-ones by Huisgen 1,3-dipolar cycloaddition with PI3Kγ isoform selective activity.

Srinivas M, Singh Pathania A, Mahajan P, Verma PK, Chobe SS, Malik FA, Nargotra A, Vishwakarma RA, Sawant SD. Srinivas M, et al. Among authors: mahajan p. Bioorg Med Chem Lett. 2018 Apr 1;28(6):1005-1010. doi: 10.1016/j.bmcl.2018.02.032. Epub 2018 Feb 16. Bioorg Med Chem Lett. 2018. PMID: 29486969

6

Design, synthesis and biological evaluation of pyrazolopyrimidinone based potent and selective PDE5 inhibitors for treatment of erectile dysfunction.

Reddy GL, Dar MI, Hudwekar AD, Mahajan P, Nargotra A, Baba AM, Nandi U, Wazir P, Singh G, Vishwakarma RA, Syed SH, Sawant SD. Reddy GL, et al. Among authors: mahajan p. Bioorg Chem. 2019 Aug;89:103022. doi: 10.1016/j.bioorg.2019.103022. Epub 2019 May 31. Bioorg Chem. 2019. PMID: 31181491

7

Corrigendum to "Design, synthesis and biological evaluation of pyrazolopyrimidinone based potent and selective PDE5 inhibitors for treatment of erectile dysfunction" [Bioorg. Chem. 89 (2019) 103022].

Reddy GL, Dar MI, Hudwekar AD, Mahajan P, Nargotra A, Baba AM, Nandi U, Wazir P, Singh G, Bharate SS, Vishwakarma RA, Syed SH, Sawant SD. Reddy GL, et al. Among authors: mahajan p. Bioorg Chem. 2019 Nov;92:103257. doi: 10.1016/j.bioorg.2019.103257. Epub 2019 Sep 13. Bioorg Chem. 2019. PMID: 31525521 No abstract available.

8

Computationally Guided Identification of Novel Mycobacterium tuberculosis GlmU Inhibitory Leads, Their Optimization, and in Vitro Validation.

Mehra R, Rani C, Mahajan P, Vishwakarma RA, Khan IA, Nargotra A. Mehra R, et al. Among authors: mahajan p. ACS Comb Sci. 2016 Feb 8;18(2):100-16. doi: 10.1021/acscombsci.5b00019. Epub 2016 Jan 28. ACS Comb Sci. 2016. PMID: 26812086

9

Synthesis of α-santonin derivatives for diminutive effect on T and B-cell proliferation and their structure activity relationships.

Chinthakindi PK, Singh J, Gupta S, Nargotra A, Mahajan P, Kaul A, Ahmed Z, Koul S, Sangwan PL. Chinthakindi PK, et al. Among authors: mahajan p. Eur J Med Chem. 2017 Feb 15;127:1047-1058. doi: 10.1016/j.ejmech.2016.11.018. Epub 2016 Nov 9. Eur J Med Chem. 2017. PMID: 27847171

10

Exploring Derivatives of Quinazoline Alkaloid l-Vasicine as Cap Groups in the Design and Biological Mechanistic Evaluation of Novel Antitumor Histone Deacetylase Inhibitors.

Ahmad M, Aga MA, Bhat JA, Kumar B, Rouf A, Capalash N, Mintoo MJ, Kumar A, Mahajan P, Mondhe DM, Nargotra A, Sharma PR, Zargar MA, Vishwakarma RA, Shah BA, Taneja SC, Hamid A. Ahmad M, et al. Among authors: mahajan p. J Med Chem. 2017 Apr 27;60(8):3484-3497. doi: 10.1021/acs.jmedchem.7b00322. Epub 2017 Apr 13. J Med Chem. 2017. PMID: 28368585

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