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Glial cell line-derived neurotrophic factor receptor Rearranged during transfection agonist supports dopamine neurons in Vitro and enhances dopamine release In Vivo.
Mahato AK, Kopra J, Renko JM, Visnapuu T, Korhonen I, Pulkkinen N, Bespalov MM, Domanskyi A, Ronken E, Piepponen TP, Voutilainen MH, Tuominen RK, Karelson M, Sidorova YA, Saarma M. Mahato AK, et al. Mov Disord. 2020 Feb;35(2):245-255. doi: 10.1002/mds.27943. Epub 2019 Dec 16. Mov Disord. 2020. PMID: 31840869 Free PMC article.
Novel RET agonist for the treatment of experimental neuropathies.
Viisanen H, Nuotio U, Kambur O, Mahato AK, Jokinen V, Lilius T, Li W, Santos HA, Karelson M, Rauhala P, Kalso E, Sidorova YA. Viisanen H, et al. Among authors: mahato ak. Mol Pain. 2020 Jan-Dec;16:1744806920950866. doi: 10.1177/1744806920950866. Mol Pain. 2020. PMID: 32811276 Free PMC article.
A Novel Small Molecule Supports the Survival of Cultured Dopamine Neurons and May Restore the Dopaminergic Innervation of the Brain in the MPTP Mouse Model of Parkinson's Disease.
Ardashov OV, Pavlova AV, Mahato AK, Sidorova Y, Morozova EA, Korchagina DV, Salnikov GE, Genaev AM, Patrusheva OS, Li-Zhulanov NS, Tolstikova TG, Volcho KP, Salakhutdinov NF. Ardashov OV, et al. Among authors: mahato ak. ACS Chem Neurosci. 2019 Oct 16;10(10):4337-4349. doi: 10.1021/acschemneuro.9b00396. Epub 2019 Sep 11. ACS Chem Neurosci. 2019. PMID: 31464415
Biological Activity In Vitro, Absorption, BBB Penetration, and Tolerability of Nanoformulation of BT44:RET Agonist with Disease-Modifying Potential for the Treatment of Neurodegeneration.
Haider MS, Mahato AK, Kotliarova A, Forster S, Böttcher B, Stahlhut P, Sidorova Y, Luxenhofer R. Haider MS, et al. Among authors: mahato ak. Biomacromolecules. 2023 Oct 9;24(10):4348-4365. doi: 10.1021/acs.biomac.2c00761. Epub 2022 Oct 11. Biomacromolecules. 2023. PMID: 36219820 Free PMC article.
Body weight regulation via MT1-MMP-mediated cleavage of GFRAL.
Chow CFW, Guo X, Asthana P, Zhang S, Wong SKK, Fallah S, Che S, Gurung S, Wang Z, Lee KB, Ge X, Yuan S, Xu H, Ip JPK, Jiang Z, Zhai L, Wu J, Zhang Y, Mahato AK, Saarma M, Lin CY, Kwan HY, Huang T, Lyu A, Zhou Z, Bian ZX, Wong HLX. Chow CFW, et al. Among authors: mahato ak. Nat Metab. 2022 Feb;4(2):203-212. doi: 10.1038/s42255-022-00529-5. Epub 2022 Feb 17. Nat Metab. 2022. PMID: 35177851
55 results