Mahling R - Search Results

1

Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel Na_V1.2.

Hovey L, Fowler CA, Mahling R, Lin Z, Miller MS, Marx DC, Yoder JB, Kim EH, Tefft KM, Waite BC, Feldkamp MD, Yu L, Shea MA. Hovey L, et al. Among authors: mahling r. Biophys Chem. 2017 May;224:1-19. doi: 10.1016/j.bpc.2017.02.006. Epub 2017 Mar 9. Biophys Chem. 2017. PMID: 28343066 Free PMC article.

2

Backbone resonance assignments of complexes of human voltage-dependent sodium channel Na_V1.2 IQ motif peptide bound to apo calmodulin and to the C-domain fragment of apo calmodulin.

Mahling R, Kilpatrick AM, Shea MA. Mahling R, et al. Biomol NMR Assign. 2017 Oct;11(2):297-303. doi: 10.1007/s12104-017-9767-2. Epub 2017 Aug 19. Biomol NMR Assign. 2017. PMID: 28823028 Free PMC article.

3

Backbone resonance assignments of complexes of apo human calmodulin bound to IQ motif peptides of voltage-dependent sodium channels Na_V1.1, Na_V1.4 and Na_V1.7.

Isbell HM, Kilpatrick AM, Lin Z, Mahling R, Shea MA. Isbell HM, et al. Among authors: mahling r. Biomol NMR Assign. 2018 Oct;12(2):283-289. doi: 10.1007/s12104-018-9824-5. Epub 2018 May 4. Biomol NMR Assign. 2018. PMID: 29728980 Free PMC article.

4

Ca²⁺-saturated calmodulin binds tightly to the N-terminal domain of A-type fibroblast growth factor homologous factors.

Mahling R, Rahlf CR, Hansen SC, Hayden MR, Shea MA. Mahling R, et al. J Biol Chem. 2021 Jan-Jun;296:100458. doi: 10.1016/j.jbc.2021.100458. Epub 2021 Feb 24. J Biol Chem. 2021. PMID: 33639159 Free PMC article.

5

Na_V1.2 EFL domain allosterically enhances Ca²⁺ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.

Mahling R, Hovey L, Isbell HM, Marx DC, Miller MS, Kilpatrick AM, Weaver LD, Yoder JB, Kim EH, Andresen CNJ, Li S, Shea MA. Mahling R, et al. Structure. 2021 Dec 2;29(12):1339-1356.e7. doi: 10.1016/j.str.2021.03.002. Epub 2021 Mar 25. Structure. 2021. PMID: 33770503 Free PMC article.

6

Synaptotagmin I's Intrinsically Disordered Region Interacts with Synaptic Vesicle Lipids and Exerts Allosteric Control over C2A.

Fealey ME, Mahling R, Rice AM, Dunleavy K, Kobany SE, Lohese KJ, Horn B, Hinderliter A. Fealey ME, et al. Among authors: mahling r. Biochemistry. 2016 May 31;55(21):2914-26. doi: 10.1021/acs.biochem.6b00085. Epub 2016 May 18. Biochemistry. 2016. PMID: 27191789

7

Alternate splicing of dysferlin C2A confers Ca²⁺-dependent and Ca²⁺-independent binding for membrane repair.

Fuson K, Rice A, Mahling R, Snow A, Nayak K, Shanbhogue P, Meyer AG, Redpath GM, Hinderliter A, Cooper ST, Sutton RB. Fuson K, et al. Among authors: mahling r. Structure. 2014 Jan 7;22(1):104-15. doi: 10.1016/j.str.2013.10.001. Epub 2013 Nov 14. Structure. 2014. PMID: 24239457 Free PMC article.

8

Randomly organized lipids and marginally stable proteins: a coupling of weak interactions to optimize membrane signaling.

Rice AM, Mahling R, Fealey ME, Rannikko A, Dunleavy K, Hendrickson T, Lohese KJ, Kruggel S, Heiling H, Harren D, Sutton RB, Pastor J, Hinderliter A. Rice AM, et al. Among authors: mahling r. Biochim Biophys Acta. 2014 Sep;1838(9):2331-40. doi: 10.1016/j.bbamem.2014.03.005. Epub 2014 Mar 21. Biochim Biophys Acta. 2014. PMID: 24657395 Free article.

9

Oxidation increases the strength of the methionine-aromatic interaction.

Lewis AK, Dunleavy KM, Senkow TL, Her C, Horn BT, Jersett MA, Mahling R, McCarthy MR, Perell GT, Valley CC, Karim CB, Gao J, Pomerantz WC, Thomas DD, Cembran A, Hinderliter A, Sachs JN. Lewis AK, et al. Among authors: mahling r. Nat Chem Biol. 2016 Oct;12(10):860-6. doi: 10.1038/nchembio.2159. Epub 2016 Aug 22. Nat Chem Biol. 2016. PMID: 27547920 Free PMC article.

10

A bridge from the endoplasmic reticulum to the plasma membrane comes into view.

Mahling R, Ben-Johny M. Mahling R, et al. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2202254119. doi: 10.1073/pnas.2202254119. Epub 2022 Mar 30. Proc Natl Acad Sci U S A. 2022. PMID: 35353604 Free PMC article. No abstract available.

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