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Indomethacin inactivates gastric peroxidase to induce reactive-oxygen-mediated gastric mucosal injury and curcumin protects it by preventing peroxidase inactivation and scavenging reactive oxygen.
Chattopadhyay I, Bandyopadhyay U, Biswas K, Maity P, Banerjee RK. Chattopadhyay I, et al. Among authors: maity p. Free Radic Biol Med. 2006 Apr 15;40(8):1397-408. doi: 10.1016/j.freeradbiomed.2005.12.016. Epub 2006 Jan 17. Free Radic Biol Med. 2006. PMID: 16631530
Translocation of heme oxygenase-1 to mitochondria is a novel cytoprotective mechanism against non-steroidal anti-inflammatory drug-induced mitochondrial oxidative stress, apoptosis, and gastric mucosal injury.
Bindu S, Pal C, Dey S, Goyal M, Alam A, Iqbal MS, Dutta S, Sarkar S, Kumar R, Maity P, Bandyopadhyay U. Bindu S, et al. Among authors: maity p. J Biol Chem. 2011 Nov 11;286(45):39387-402. doi: 10.1074/jbc.M111.279893. Epub 2011 Sep 9. J Biol Chem. 2011. PMID: 21908612 Free PMC article.
Lansoprazole protects and heals gastric mucosa from non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy by inhibiting mitochondrial as well as Fas-mediated death pathways with concurrent induction of mucosal cell renewal.
Maity P, Bindu S, Choubey V, Alam A, Mitra K, Goyal M, Dey S, Guha M, Pal C, Bandyopadhyay U. Maity P, et al. J Biol Chem. 2008 May 23;283(21):14391-401. doi: 10.1074/jbc.M800414200. Epub 2008 Mar 28. J Biol Chem. 2008. PMID: 18375387 Free article. Retracted.
Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive oxygen species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: a novel role of mitochondrial aconitase oxidation.
Maity P, Bindu S, Dey S, Goyal M, Alam A, Pal C, Mitra K, Bandyopadhyay U. Maity P, et al. J Biol Chem. 2009 Jan 30;284(5):3058-3068. doi: 10.1074/jbc.M805329200. Epub 2008 Dec 2. J Biol Chem. 2009. PMID: 19049974 Free article.
349 results