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Sulfated bile acid is a host-derived ligand for MAIT cells.
Ito E, Inuki S, Izumi Y, Takahashi M, Dambayashi Y, Ciacchi L, Awad W, Takeyama A, Shibata K, Mori S, Mak JYW, Fairlie DP, Bamba T, Ishikawa E, Nagae M, Rossjohn J, Yamasaki S. Ito E, et al. Among authors: mak jyw. Sci Immunol. 2024 Jan 26;9(91):eade6924. doi: 10.1126/sciimmunol.ade6924. Epub 2024 Jan 26. Sci Immunol. 2024. PMID: 38277465
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies.
Kammann T, Gorin JB, Parrot T, Gao Y, Ponzetta A, Emgård J, Maleki KT, Sekine T, Rivera-Ballesteros O; Karolinska COVID-19 Study Group; Gredmark-Russ S, Rooyackers O, Skagerberg M, Eriksson LI, Norrby-Teglund A, Mak JYW, Fairlie DP, Björkström NK, Klingström J, Ljunggren HG, Aleman S, Buggert M, Strålin K, Sandberg JK. Kammann T, et al. Among authors: mak jyw. J Immunol. 2024 Feb 1;212(3):389-396. doi: 10.4049/jimmunol.2300639. J Immunol. 2024. PMID: 38117799 Free PMC article.
Synthetic 5-amino-6-D-ribitylaminouracil paired with inflammatory stimuli facilitates MAIT cell expansion in vivo.
Nelson AG, Wang H, Dewar PM, Eddy EM, Li S, Lim XY, Patton T, Zhou Y, Pediongco TJ, Meehan LJ, Meehan BS, Mak JYW, Fairlie DP, Stent AW, Kjer-Nielsen L, McCluskey J, Eckle SBG, Corbett AJ, Souter MNT, Chen Z. Nelson AG, et al. Among authors: mak jyw. Front Immunol. 2023 Aug 31;14:1109759. doi: 10.3389/fimmu.2023.1109759. eCollection 2023. Front Immunol. 2023. PMID: 37720229 Free PMC article.
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells.
Lim HJ, Wubben JM, Garcia CP, Cruz-Gomez S, Deng J, Mak JYW, Hachani A, Anderson RJ, Painter GF, Goyette J, Amarasinghe SL, Ritchie ME, Roquilly A, Fairlie DP, Gaus K, Rossjohn J, Villadangos JA, McWilliam HEG. Lim HJ, et al. Among authors: mak jyw. J Cell Biol. 2022 Dec 5;221(12):e202110125. doi: 10.1083/jcb.202110125. Epub 2022 Sep 21. J Cell Biol. 2022. PMID: 36129434 Free PMC article.
CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells.
Souter MNT, Awad W, Li S, Pediongco TJ, Meehan BS, Meehan LJ, Tian Z, Zhao Z, Wang H, Nelson A, Le Nours J, Khandokar Y, Praveena T, Wubben J, Lin J, Sullivan LC, Lovrecz GO, Mak JYW, Liu L, Kostenko L, Kedzierska K, Corbett AJ, Fairlie DP, Brooks AG, Gherardin NA, Uldrich AP, Chen Z, Rossjohn J, Godfrey DI, McCluskey J, Pellicci DG, Eckle SBG. Souter MNT, et al. Among authors: mak jyw. J Exp Med. 2022 Sep 5;219(9):e20210828. doi: 10.1084/jem.20210828. Epub 2022 Aug 26. J Exp Med. 2022. PMID: 36018322 Free PMC article.
67 results