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Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.
Manfredsson FP, Luk KC, Benskey MJ, Gezer A, Garcia J, Kuhn NC, Sandoval IM, Patterson JR, O'Mara A, Yonkers R, Kordower JH. Manfredsson FP, et al. Neurobiol Dis. 2018 Apr;112:106-118. doi: 10.1016/j.nbd.2018.01.008. Epub 2018 Jan 16. Neurobiol Dis. 2018. PMID: 29341898 Free PMC article.
Gene Therapy to Modulate Alpha-Synuclein in Synucleinopathies.
Sandoval IM, Marmion DJ, Meyers KT, Manfredsson FP. Sandoval IM, et al. Among authors: manfredsson fp. J Parkinsons Dis. 2021;11(s2):S189-S197. doi: 10.3233/JPD-212679. J Parkinsons Dis. 2021. PMID: 34092656 Free PMC article. Review.
Lateralized deficits after unilateral AAV-vector based overexpression of alpha-synuclein in the midbrain of rats on drug-free behavioral tests.
Gubinelli F, Cazzolla G, Negrini M, Kulacz I, Mehrdadian A, Tomasello G, Venuti C, Sarauskyte L, Jacobs F, Manfredsson FP, Davidsson M, Heuer A. Gubinelli F, et al. Among authors: manfredsson fp. Behav Brain Res. 2022 Jul 5;429:113887. doi: 10.1016/j.bbr.2022.113887. Epub 2022 Apr 8. Behav Brain Res. 2022. PMID: 35405174 Free article.
GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6-OHDA Nigrostriatal Lesion.
Kasanga EA, Owens CL, Cantu MA, Richard AD, Davis RW, McDivitt LM, Blancher B, Pruett BS, Tan C, Gajewski A, Manfredsson FP, Nejtek VA, Salvatore MF. Kasanga EA, et al. Among authors: manfredsson fp. ACS Chem Neurosci. 2019 Oct 16;10(10):4237-4249. doi: 10.1021/acschemneuro.9b00291. Epub 2019 Oct 8. ACS Chem Neurosci. 2019. PMID: 31538765
98 results