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Page 1
Phosphodiesterase type 3A regulates basal myocardial contractility through interacting with sarcoplasmic reticulum calcium ATPase type 2a signaling complexes in mouse heart.
Beca S, Ahmad F, Shen W, Liu J, Makary S, Polidovitch N, Sun J, Hockman S, Chung YW, Movsesian M, Murphy E, Manganiello V, Backx PH. Beca S, et al. Among authors: manganiello v. Circ Res. 2013 Jan 18;112(2):289-97. doi: 10.1161/CIRCRESAHA.111.300003. Epub 2012 Nov 19. Circ Res. 2013. PMID: 23168336 Free PMC article.
Phosphodiesterase 4D regulates baseline sarcoplasmic reticulum Ca2+ release and cardiac contractility, independently of L-type Ca2+ current.
Beca S, Helli PB, Simpson JA, Zhao D, Farman GP, Jones P, Tian X, Wilson LS, Ahmad F, Chen SRW, Movsesian MA, Manganiello V, Maurice DH, Conti M, Backx PH. Beca S, et al. Among authors: manganiello v. Circ Res. 2011 Oct 14;109(9):1024-1030. doi: 10.1161/CIRCRESAHA.111.250464. Epub 2011 Sep 8. Circ Res. 2011. PMID: 21903937 Free PMC article.
Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury.
Chung YW, Lagranha C, Chen Y, Sun J, Tong G, Hockman SC, Ahmad F, Esfahani SG, Bae DH, Polidovitch N, Wu J, Rhee DK, Lee BS, Gucek M, Daniels MP, Brantner CA, Backx PH, Murphy E, Manganiello VC. Chung YW, et al. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2253-62. doi: 10.1073/pnas.1416230112. Epub 2015 Apr 15. Proc Natl Acad Sci U S A. 2015. PMID: 25877153 Free PMC article.
Regulation of sarcoplasmic reticulum Ca2+ ATPase 2 (SERCA2) activity by phosphodiesterase 3A (PDE3A) in human myocardium: phosphorylation-dependent interaction of PDE3A1 with SERCA2.
Ahmad F, Shen W, Vandeput F, Szabo-Fresnais N, Krall J, Degerman E, Goetz F, Klussmann E, Movsesian M, Manganiello V. Ahmad F, et al. Among authors: manganiello v. J Biol Chem. 2015 Mar 13;290(11):6763-76. doi: 10.1074/jbc.M115.638585. Epub 2015 Jan 15. J Biol Chem. 2015. PMID: 25593322 Free PMC article.
Cyclic nucleotide phosphodiesterase 3 signaling complexes.
Ahmad F, Degerman E, Manganiello VC. Ahmad F, et al. Among authors: manganiello vc. Horm Metab Res. 2012 Sep;44(10):776-85. doi: 10.1055/s-0032-1312646. Epub 2012 Jun 12. Horm Metab Res. 2012. PMID: 22692928 Review.
Advances in targeting cyclic nucleotide phosphodiesterases.
Maurice DH, Ke H, Ahmad F, Wang Y, Chung J, Manganiello VC. Maurice DH, et al. Nat Rev Drug Discov. 2014 Apr;13(4):290-314. doi: 10.1038/nrd4228. Nat Rev Drug Discov. 2014. PMID: 24687066 Free PMC article. Review.
235 results