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Eleven amino acid glucagon-like peptide-1 receptor agonists with antidiabetic activity.
Mapelli C, Natarajan SI, Meyer JP, Bastos MM, Bernatowicz MS, Lee VG, Pluscec J, Riexinger DJ, Sieber-McMaster ES, Constantine KL, Smith-Monroy CA, Golla R, Ma Z, Longhi DA, Shi D, Xin L, Taylor JR, Koplowitz B, Chi CL, Khanna A, Robinson GW, Seethala R, Antal-Zimanyi IA, Stoffel RH, Han S, Whaley JM, Huang CS, Krupinski J, Ewing WR. Mapelli C, et al. J Med Chem. 2009 Dec 10;52(23):7788-99. doi: 10.1021/jm900752a. J Med Chem. 2009. PMID: 19702274
Micelle-bound conformational preferences of a peptide derived from a murine major histocompatibility complex class I molecule.
Constantine KL, Mapelli C, Meyers CA, Friedrichs MS, Krystek S, Mueller L. Constantine KL, et al. Among authors: mapelli c. J Biol Chem. 1993 Oct 25;268(30):22830-7. J Biol Chem. 1993. PMID: 8226794 Free article.
J., Saper, M. A., Bjorkmann, P. J., Strominger, T. L., and Wiley, D. C. (1989) Nature 342, 692-696). Structural features that are important for the bioactivity of [Ala85]Dk(69-85) are discussed with reference to reported structure-activity relationships (Stagsted, J., M …
J., Saper, M. A., Bjorkmann, P. J., Strominger, T. L., and Wiley, D. C. (1989) Nature 342, 692-696). Structural features that are imp …
NEMO binding domain of IKK-2 encompasses amino acids 735-745.
Strnad J, McDonnell PA, Riexinger DJ, Mapelli C, Cheng L, Gray H, Ryseck RP, Burke JR. Strnad J, et al. Among authors: mapelli c. J Mol Recognit. 2006 May-Jun;19(3):227-33. doi: 10.1002/jmr.766. J Mol Recognit. 2006. PMID: 16583354
Exploration of structure-activity relationships at the two C-terminal residues of potent 11mer Glucagon-Like Peptide-1 receptor agonist peptides via parallel synthesis.
Haque TS, Martinez RL, Lee VG, Riexinger DG, Lei M, Feng M, Koplowitz B, Mapelli C, Cooper CB, Zhang G, Huang C, Ewing WR, Krupinski J. Haque TS, et al. Among authors: mapelli c. Peptides. 2010 Jul;31(7):1353-60. doi: 10.1016/j.peptides.2010.04.013. Epub 2010 Apr 24. Peptides. 2010. PMID: 20420872
Synthesis of a stable isotopically labeled universal surrogate peptide for use as an internal standard in LC-MS/MS bioanalysis of human IgG and Fc-fusion protein drug candidates.
Voronin K, Allentoff AJ, Bonacorsi SJ Jr, Mapelli C, Gong SX, Lee V, Riexinger D, Sanghvi N, Jiang H, Zeng J. Voronin K, et al. Among authors: mapelli c. J Labelled Comp Radiopharm. 2014 Jul;57(9):579-83. doi: 10.1002/jlcr.3218. Epub 2014 Aug 4. J Labelled Comp Radiopharm. 2014. PMID: 25089024
87 results