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Year Number of Results
1998 1
1999 7
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2001 14
2002 11
2003 19
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2005 13
2006 6
2007 11
2008 7
2009 6
2010 5
2011 4
2012 7
2013 7
2014 4
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2016 5
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165 results

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Page 1
MAPK8IP1/JIP1 regulates the trafficking of autophagosomes in neurons.
Fu MM, Holzbaur EL. Fu MM, et al. Autophagy. 2014;10(11):2079-81. doi: 10.4161/auto.34451. Epub 2014 Oct 30. Autophagy. 2014. PMID: 25483967 Free PMC article.
Here, we discuss our recent work identifying the scaffolding protein MAPK8IP1/JIP1 (mitogen-activated protein kinase 8 interacting protein 1) as a key regulator of autophagosome transport in neurons. MAPK8IP1 tightly coordinates motor activity to ensure the fidelity …
Here, we discuss our recent work identifying the scaffolding protein MAPK8IP1/JIP1 (mitogen-activated protein kinase 8 interacting pr …
The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes.
Waeber G, Delplanque J, Bonny C, Mooser V, Steinmann M, Widmann C, Maillard A, Miklossy J, Dina C, Hani EH, Vionnet N, Nicod P, Boutin P, Froguel P. Waeber G, et al. Nat Genet. 2000 Mar;24(3):291-5. doi: 10.1038/73523. Nat Genet. 2000. PMID: 10700186
In addition, we detected MAPK8IP1 transcripts and IBi protein in human pancreatic islets. These data establish MAPK8IP1 as a candidate gene for human diabetes. Sibpair analyses performed on i49 multiplex French families with type 2 diabetes excluded MAPK8IP1 …
In addition, we detected MAPK8IP1 transcripts and IBi protein in human pancreatic islets. These data establish MAPK8IP1 as a c …
Direct targeting of MAPK8IP1 by miR-10a-5p is a major mechanism for gastric cancer metastasis.
Lu Y, Wei G, Liu L, Mo Y, Chen Q, Xu L, Liao R, Zeng D, Zhang K. Lu Y, et al. Oncol Lett. 2017 Mar;13(3):1131-1136. doi: 10.3892/ol.2016.5544. Epub 2016 Dec 28. Oncol Lett. 2017. PMID: 28454224 Free PMC article.
Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) analysis demonstrated that MAPK8IP1 was significant downregulated in GC tissue. A statistically significant inverse correlation was detected between miR-10a and MAPK8IP1 mRNA expression levels in …
Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) analysis demonstrated that MAPK8IP1 was significant downregula …
Jump-starting kinesin.
Hackney DD. Hackney DD. J Cell Biol. 2007 Jan 1;176(1):7-9. doi: 10.1083/jcb.200611082. J Cell Biol. 2007. PMID: 17200413 Free PMC article.
Expression Silencing of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 Conferred Its Role in Pancreatic β-Cell Physiology and Insulin Secretion.
Saeed R, Mohammed AK, Saleh SE, Aboshanab KM, Aboulwafa MM, Taneera J. Saeed R, et al. Metabolites. 2023 Feb 20;13(2):307. doi: 10.3390/metabo13020307. Metabolites. 2023. PMID: 36837926 Free PMC article.
Mitogen-activated protein kinase 8 interacting protein-1 (MAPK8IP1) gene has been recognized as a susceptibility gene for diabetes. ...Additionally, comparable expression of MAPK8IP1 expression was detected in sorted human endocrine cells. However, beta-cells exhibi …
Mitogen-activated protein kinase 8 interacting protein-1 (MAPK8IP1) gene has been recognized as a susceptibility gene for diabetes. . …
Dual Role of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 in Inflammasome and Pancreatic β-Cell Function.
Saeed R, Mohammed AK, Saleh SE, Aboulwafa MM, Aboshanab KM, Taneera J. Saeed R, et al. Int J Mol Sci. 2023 Mar 5;24(5):4990. doi: 10.3390/ijms24054990. Int J Mol Sci. 2023. PMID: 36902422 Free PMC article.
The precise role of MAPK8IP1 in inflammasome activation in beta-cells has not been defined. ...Nonetheless, silencing of Mapk8ip1 failed to preserve beta-cell function against inflammasome response. ...
The precise role of MAPK8IP1 in inflammasome activation in beta-cells has not been defined. ...Nonetheless, silencing of Mapk8ip1 …
Autophagy-related gene expression is an independent prognostic indicator of glioma.
Zhang H, Lu X, Wang N, Wang J, Cao Y, Wang T, Zhou X, Jiao Y, Yang L, Wang X, Cong L, Li J, Li J, Ma HP, Pan Y, Ning S, Wang L. Zhang H, et al. Oncotarget. 2017 May 9;8(37):60987-61000. doi: 10.18632/oncotarget.17719. eCollection 2017 Sep 22. Oncotarget. 2017. PMID: 28977840 Free PMC article.
MAPK8IP1 overexpression and SH3GLB1 knockdown inhibited glioma cell proliferation, migration and invasion, and improved Temozolomide sensitivity. These findings suggest autophagy-related genes like MAPK8IP1 and SH3GLB1 could be potential therapeutic targets in gliom …
MAPK8IP1 overexpression and SH3GLB1 knockdown inhibited glioma cell proliferation, migration and invasion, and improved Temozolomide …
Kinesin carries the signal.
Verhey KJ, Rapoport TA. Verhey KJ, et al. Trends Biochem Sci. 2001 Sep;26(9):545-50. doi: 10.1016/s0968-0004(01)01931-4. Trends Biochem Sci. 2001. PMID: 11551791 Review.
The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1).
Abderrahmani A, Steinmann M, Plaisance V, Niederhauser G, Haefliger JA, Mooser V, Bonny C, Nicod P, Waeber G. Abderrahmani A, et al. Mol Cell Biol. 2001 Nov;21(21):7256-67. doi: 10.1128/MCB.21.21.7256-7267.2001. Mol Cell Biol. 2001. PMID: 11585908 Free PMC article.
A 731-bp fragment of the 5' regulatory region of the human MAPK8IP1 gene was isolated from a human BAC library and cloned upstream of a luciferase reporter gene. ...
A 731-bp fragment of the 5' regulatory region of the human MAPK8IP1 gene was isolated from a human BAC library and cloned upstream of …
Identification of Key Biomarkers and Immune Infiltration in Sporadic Vestibular Schwannoma Basing Transcriptome-Wide Profiling.
Shi J, Lu D, Gu R, Xu Y, Pan R, Bo F, Zhang Y. Shi J, et al. World Neurosurg. 2022 Apr;160:e591-e600. doi: 10.1016/j.wneu.2022.01.077. Epub 2022 Jan 29. World Neurosurg. 2022. PMID: 35092815
RESULTS: A total of 39 significantly enriched in myelination and collagen-containing extracellular matrix DEGs were identified at the screening step. Three hub genes (MAPK8IP1, SLC36A2, and OR2AT4) were identified, which mainly enriched in pathways of melanogenesis, GnRH, …
RESULTS: A total of 39 significantly enriched in myelination and collagen-containing extracellular matrix DEGs were identified at the screen …
165 results