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Identification of a novel boron-containing antibacterial agent (AN0128) with anti-inflammatory activity, for the potential treatment of cutaneous diseases.
Baker SJ, Akama T, Zhang YK, Sauro V, Pandit C, Singh R, Kully M, Khan J, Plattner JJ, Benkovic SJ, Lee V, Maples KR. Baker SJ, et al. Among authors: maples kr. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5963-7. doi: 10.1016/j.bmcl.2006.08.130. Epub 2006 Sep 25. Bioorg Med Chem Lett. 2006. PMID: 16997550
Discovery and structure-activity study of a novel benzoxaborole anti-inflammatory agent (AN2728) for the potential topical treatment of psoriasis and atopic dermatitis.
Akama T, Baker SJ, Zhang YK, Hernandez V, Zhou H, Sanders V, Freund Y, Kimura R, Maples KR, Plattner JJ. Akama T, et al. Among authors: maples kr. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2129-32. doi: 10.1016/j.bmcl.2009.03.007. Epub 2009 Mar 9. Bioorg Med Chem Lett. 2009. PMID: 19303290
Boron-based phosphodiesterase inhibitors show novel binding of boron to PDE4 bimetal center.
Freund YR, Akama T, Alley MR, Antunes J, Dong C, Jarnagin K, Kimura R, Nieman JA, Maples KR, Plattner JJ, Rock F, Sharma R, Singh R, Sanders V, Zhou Y. Freund YR, et al. Among authors: maples kr. FEBS Lett. 2012 Sep 21;586(19):3410-4. doi: 10.1016/j.febslet.2012.07.058. Epub 2012 Jul 25. FEBS Lett. 2012. PMID: 22841723 Free article.
Translational research involving oxidative stress and diseases of aging.
Floyd RA, Towner RA, He T, Hensley K, Maples KR. Floyd RA, et al. Among authors: maples kr. Free Radic Biol Med. 2011 Sep 1;51(5):931-41. doi: 10.1016/j.freeradbiomed.2011.04.014. Epub 2011 Apr 14. Free Radic Biol Med. 2011. PMID: 21549833 Free PMC article. Review.
26 results