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Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy.
Ravi R, Noonan KA, Pham V, Bedi R, Zhavoronkov A, Ozerov IV, Makarev E, V Artemov A, Wysocki PT, Mehra R, Nimmagadda S, Marchionni L, Sidransky D, Borrello IM, Izumchenko E, Bedi A. Ravi R, et al. Among authors: marchionni l. Nat Commun. 2018 Feb 21;9(1):741. doi: 10.1038/s41467-017-02696-6. Nat Commun. 2018. PMID: 29467463 Free PMC article.
TP53 structure-function relationships in metastatic castrate-sensitive prostate cancer and the impact of APR-246 treatment.
Hoang T, Sutera P, Nguyen T, Chang J, Jagtap S, Song Y, Shetty AC, Chowdhury DD, Chan A, Carrieri FA, Hathout L, Ennis R, Jabbour SK, Parikh R, Molitoris J, Song DY, DeWeese T, Marchionni L, Ren L, Sawant A, Simone N, Lafargue A, Van Der Eecken K, Bunz F, Ost P, Tran PT, Deek MP. Hoang T, et al. Among authors: marchionni l. Prostate. 2024 Jan;84(1):87-99. doi: 10.1002/pros.24629. Epub 2023 Oct 9. Prostate. 2024. PMID: 37812042
Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer.
Guerrero-Preston R, Michailidi C, Marchionni L, Pickering CR, Frederick MJ, Myers JN, Yegnasubramanian S, Hadar T, Noordhuis MG, Zizkova V, Fertig E, Agrawal N, Westra W, Koch W, Califano J, Velculescu VE, Sidransky D. Guerrero-Preston R, et al. Among authors: marchionni l. Epigenetics. 2014 Jul;9(7):1031-46. doi: 10.4161/epi.29025. Epub 2014 May 1. Epigenetics. 2014. PMID: 24786473 Free PMC article.
Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.
Isella C, Brundu F, Bellomo SE, Galimi F, Zanella E, Porporato R, Petti C, Fiori A, Orzan F, Senetta R, Boccaccio C, Ficarra E, Marchionni L, Trusolino L, Medico E, Bertotti A. Isella C, et al. Among authors: marchionni l. Nat Commun. 2017 May 31;8:15107. doi: 10.1038/ncomms15107. Nat Commun. 2017. PMID: 28561063 Free PMC article.
YAP1 and COX2 Coordinately Regulate Urothelial Cancer Stem-like Cells.
Ooki A, Del Carmen Rodriguez Pena M, Marchionni L, Dinalankara W, Begum A, Hahn NM, VandenBussche CJ, Rasheed ZA, Mao S, Netto GJ, Sidransky D, Hoque MO. Ooki A, et al. Among authors: marchionni l. Cancer Res. 2018 Jan 1;78(1):168-181. doi: 10.1158/0008-5472.CAN-17-0836. Epub 2017 Nov 27. Cancer Res. 2018. PMID: 29180467 Free PMC article.
JAK3 Variant, Immune Signatures, DNA Methylation, and Social Determinants Linked to Survival Racial Disparities in Head and Neck Cancer Patients.
Guerrero-Preston R, Lawson F, Rodriguez-Torres S, Noordhuis MG, Pirini F, Manuel L, Valle BL, Hadar T, Rivera B, Folawiyo O, Baez A, Marchionni L, Koch WM, Westra WH, Kim YJ, Eshleman JR, Sidransky D. Guerrero-Preston R, et al. Among authors: marchionni l. Cancer Prev Res (Phila). 2019 Apr;12(4):255-270. doi: 10.1158/1940-6207.CAPR-17-0356. Epub 2019 Feb 18. Cancer Prev Res (Phila). 2019. PMID: 30777857 Free PMC article.
GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma.
Hayashi M, Guida E, Inokawa Y, Goldberg R, Reis LO, Ooki A, Pilli M, Sadhukhan P, Woo J, Choi W, Izumchenko E, Gonzalez LM, Marchionni L, Zhavoronkov A, Brait M, Bivalacqua T, Baras A, Netto GJ, Koch W, Singh A, Hoque MO. Hayashi M, et al. Among authors: marchionni l. Sci Signal. 2020 Aug 18;13(645):eaba0443. doi: 10.1126/scisignal.aba0443. Sci Signal. 2020. PMID: 32817372
159 results