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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1949 2
1950 1
1951 1
1953 1
1955 2
1956 2
1957 2
1958 1
1959 3
1961 1
1964 3
1966 3
1967 1
1968 2
1969 2
1977 2
1981 1
1988 1
1989 5
1990 6
1991 21
1992 33
1993 34
1994 36
1995 40
1996 48
1997 23
1998 41
1999 33
2000 44
2001 25
2002 33
2003 30
2004 29
2005 31
2006 31
2007 29
2008 32
2009 37
2010 26
2011 21
2012 31
2013 32
2014 40
2015 40
2016 35
2017 29
2018 29
2019 30
2020 27
2021 33
2022 32
2023 39
2024 18

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1,065 results

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Page 1
MARCKS and Lung Disease.
Sheats MK, Yin Q, Fang S, Park J, Crews AL, Parikh I, Dickson B, Adler KB. Sheats MK, et al. Am J Respir Cell Mol Biol. 2019 Jan;60(1):16-27. doi: 10.1165/rcmb.2018-0285TR. Am J Respir Cell Mol Biol. 2019. PMID: 30339463 Free PMC article. Review.
This article summarizes the structure and cellular function of MARCKS (also including MARCKS family proteins and MARCKSL1 [MARCKS-like protein 1]). Evidence for MARCKS's role in several lung diseases is discussed, as are the technological innovations t …
This article summarizes the structure and cellular function of MARCKS (also including MARCKS family proteins and MARCKSL1 [ …
The Role of MARCKS in Metastasis and Treatment Resistance of Solid Tumors.
Chiu CL, Zhao H, Chen CH, Wu R, Brooks JD. Chiu CL, et al. Cancers (Basel). 2022 Oct 8;14(19):4925. doi: 10.3390/cancers14194925. Cancers (Basel). 2022. PMID: 36230850 Free PMC article. Review.
Aberrant MARCKS signaling has been observed in the development and progression of multiple cancer types. ...In this review, we describe MARCKS protein structure, cellular localization, and biological functions. ...
Aberrant MARCKS signaling has been observed in the development and progression of multiple cancer types. ...In this review, we descri …
MARCKS and MARCKS-like proteins in development and regeneration.
El Amri M, Fitzgerald U, Schlosser G. El Amri M, et al. J Biomed Sci. 2018 May 22;25(1):43. doi: 10.1186/s12929-018-0445-1. J Biomed Sci. 2018. PMID: 29788979 Free PMC article. Review.
BACKGROUND: The Myristoylated Alanine-Rich C-kinase Substrate (MARCKS) and MARCKS-like protein 1 (MARCKSL1) have a wide range of functions, ranging from roles in embryonic development to adult brain plasticity and the inflammatory response. ...CONCLUSION: This revie …
BACKGROUND: The Myristoylated Alanine-Rich C-kinase Substrate (MARCKS) and MARCKS-like protein 1 (MARCKSL1) have a wide range …
The myristoylated alanine-rich C-kinase substrates (MARCKS): A membrane-anchored mediator of the cell function.
Chen Z, Zhang W, Selmi C, Ridgway WM, Leung PSC, Zhang F, Gershwin ME. Chen Z, et al. Autoimmun Rev. 2021 Nov;20(11):102942. doi: 10.1016/j.autrev.2021.102942. Epub 2021 Sep 10. Autoimmun Rev. 2021. PMID: 34509657 Free PMC article. Review.
MARCKS includes an N-terminal myristoylated domain for membrane binding, a highly conserved MARCKS Homology 2 (MH2) domain, and an effector domain (which is the phosphorylation site). ...From a clinical point of view, MARCKS is overexpressed in patients with …
MARCKS includes an N-terminal myristoylated domain for membrane binding, a highly conserved MARCKS Homology 2 (MH2) domain, an …
MARCKS as a Potential Therapeutic Target in Inflammatory Breast Cancer.
Manai M, ELBini-Dhouib I, Finetti P, Bichiou H, Reduzzi C, Aissaoui D, Ben-Hamida N, Agavnian E, Srairi-Abid N, Lopez M, Amri F, Guizani-Tabbane L, Rahal K, Mrad K, Manai M, Birnbaum D, Mamessier E, Cristofanilli M, Boussen H, Kharrat M, Doghri R, Bertucci F. Manai M, et al. Cells. 2022 Sep 19;11(18):2926. doi: 10.3390/cells11182926. Cells. 2022. PMID: 36139501 Free PMC article.
MARCKS has been associated with the PI3K/AKT pathway. MARCKS inhibitors are in development. ...In conclusion, our results uncover a functional role of MARCKS implicated in IBC aggressiveness. Associated with the good-prognosis value of the MARCKS-/PTEN …
MARCKS has been associated with the PI3K/AKT pathway. MARCKS inhibitors are in development. ...In conclusion, our results unco …
MARCKS: a case of molecular exaptation?
Ramsden JJ. Ramsden JJ. Int J Biochem Cell Biol. 2000 May;32(5):475-9. doi: 10.1016/s1357-2725(99)00152-1. Int J Biochem Cell Biol. 2000. PMID: 10736562 Review.
MARCKS (myristoylated alanine-rich C kinase substrate, 32 kDa) and its 20 kDa brother MARCKS-related protein (MRP) are abundant, widely distributed proteins unusually rich in alanine and glutamic acid, and with lysines, serines and phenylalanines concentrated in a c …
MARCKS (myristoylated alanine-rich C kinase substrate, 32 kDa) and its 20 kDa brother MARCKS-related protein (MRP) are abundan …
MARCKS is a New Prognostic Biomarker in Hepatocellular Carcinoma.
Lu H, Zhao R, Qin Q, Tang L, Ma G, He B, Liang J, Wei L, Wang X, Bie Q, Wang X, Zhang B. Lu H, et al. Int J Gen Med. 2023 May 1;16:1603-1619. doi: 10.2147/IJGM.S408651. eCollection 2023. Int J Gen Med. 2023. PMID: 37152272 Free PMC article.
The purpose of our study was to evaluate the role of MARCKS in HCC. METHODS: The role of MARCKS in HCC was explored by bioinformatics and experiment. RESULTS: We demonstrated that MARCKS expression was significantly elevated in HCC datasets of TCGA. ...
The purpose of our study was to evaluate the role of MARCKS in HCC. METHODS: The role of MARCKS in HCC was explored by bioinfo …
Myristoylated alanine-rich C kinase substrate (MARCKS): a multirole signaling protein in cancers.
Fong LWR, Yang DC, Chen CH. Fong LWR, et al. Cancer Metastasis Rev. 2017 Dec;36(4):737-747. doi: 10.1007/s10555-017-9709-6. Cancer Metastasis Rev. 2017. PMID: 29039083 Review.
MARCKS is tethered to the plasma membrane but can shuttle between the cytosol and plasma membrane via the myristoyl-electrostatic switch. ...This review highlights the molecular and functional differences of MARCKS that exist between normal and tumor cells. We also …
MARCKS is tethered to the plasma membrane but can shuttle between the cytosol and plasma membrane via the myristoyl-electrostatic swi …
Cross-talk unfolded: MARCKS proteins.
Arbuzova A, Schmitz AA, Vergères G. Arbuzova A, et al. Biochem J. 2002 Feb 15;362(Pt 1):1-12. doi: 10.1042/0264-6021:3620001. Biochem J. 2002. PMID: 11829734 Free PMC article. Review.
The proteins of the MARCKS (myristoylated alanine-rich C kinase substrate) family were first identified as prominent substrates of protein kinase C (PKC). ...Finally, studies with mice lacking MARCKS proteins have investigated the functions of these proteins during …
The proteins of the MARCKS (myristoylated alanine-rich C kinase substrate) family were first identified as prominent substrates of pr …
Pathophysiological roles of myristoylated alanine-rich C-kinase substrate (MARCKS) in hematological malignancies.
Iyer DN, Faruq O, Zhang L, Rastgoo N, Liu A, Chang H. Iyer DN, et al. Biomark Res. 2021 May 6;9(1):34. doi: 10.1186/s40364-021-00286-9. Biomark Res. 2021. PMID: 33958003 Free PMC article. Review.
While it is understood that MARCKS impacts the overall carcinogenesis as well as plays a part in determining the disease outcome in blood cancers, we are still at an early stage of interpreting the pathophysiological roles of MARCKS in neoplastic disease. ...Additio …
While it is understood that MARCKS impacts the overall carcinogenesis as well as plays a part in determining the disease outcome in b …
1,065 results