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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1987 1
2000 1
2002 4
2003 2
2004 5
2005 5
2006 3
2007 3
2008 7
2009 4
2010 5
2011 5
2012 13
2013 4
2014 1
2015 3
2016 8
2017 8
2018 9
2019 10
2020 11
2021 13
2022 9
2023 8
2024 5

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124 results

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Page 1
Effect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial.
UK TAVI Trial Investigators; Toff WD, Hildick-Smith D, Kovac J, Mullen MJ, Wendler O, Mansouri A, Rombach I, Abrams KR, Conroy SP, Flather MD, Gray AM, MacCarthy P, Monaghan MJ, Prendergast B, Ray S, Young CP, Crossman DC, Cleland JGF, de Belder MA, Ludman PF, Jones S, Densem CG, Tsui S, Kuduvalli M, Mills JD, Banning AP, Sayeed R, Hasan R, Fraser DGW, Trivedi U, Davies SW, Duncan A, Curzen N, Ohri SK, Malkin CJ, Kaul P, Muir DF, Owens WA, Uren NG, Pessotto R, Kennon S, Awad WI, Khogali SS, Matuszewski M, Edwards RJ, Ramesh BC, Dalby M, Raja SG, Mariscalco G, Lloyd C, Cox ID, Redwood SR, Gunning MG, Ridley PD. UK TAVI Trial Investigators, et al. JAMA. 2022 May 17;327(19):1875-1887. doi: 10.1001/jama.2022.5776. JAMA. 2022. PMID: 35579641 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: In this randomized clinical trial conducted at 34 UK centers, 913 patients aged 70 years or older with severe, symptomatic aortic stenosis and moderately increased operative risk due to age or comorbidity were enrolled between April 2014 and Apr …
DESIGN, SETTING, AND PARTICIPANTS: In this randomized clinical trial conducted at 34 UK centers, 913 patients aged 70 years or older with se …
Doug Altman, medical statistician par excellence: What can radiologists learn from his legacy?
Halligan S, Boone D, Burling D, Helbren E, Mallett S, Plumb A. Halligan S, et al. Clin Radiol. 2024 Apr 17:S0009-9260(24)00195-8. doi: 10.1016/j.crad.2024.04.004. Online ahead of print. Clin Radiol. 2024. PMID: 38729906 Free article. Review.
This narrative review describes our experience of working with Doug Altman, the most highly cited medical statistician in the world. Doug was particularly interested in diagnostics, and imaging studies in particular. ...
This narrative review describes our experience of working with Doug Altman, the most highly cited medical statistician in the world. …
Variant Interpretation in Current Pharmacogenetic Testing.
Luvsantseren S, Whirl-Carrillo M, Sangkuhl K, Shin N, Wen A, Empey P, Alam B, David S, Dunnenberger HM, Orlando L, Altman R, Palaniappan L. Luvsantseren S, et al. J Pers Med. 2020 Oct 31;10(4):204. doi: 10.3390/jpm10040204. J Pers Med. 2020. PMID: 33142667 Free PMC article.
MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation.
Haidle AM, Childers KK, Zabierek AA, Katz JD, Jewell JP, Hou Y, Altman MD, Szewczak A, Chen D, Harsch A, Hayashi M, Warren L, Hutton M, Nuthall H, Stanton MG, Davies IW, Munoz B, Northrup A. Haidle AM, et al. Bioorg Med Chem Lett. 2017 Jan 1;27(1):109-113. doi: 10.1016/j.bmcl.2016.08.066. Epub 2016 Aug 25. Bioorg Med Chem Lett. 2017. PMID: 27894874
Attempts to optimize pharmacokinetic properties in a promising series of pyrrolopyrimidinone MARK inhibitors for the treatment of Alzheimer's disease are described. ...
Attempts to optimize pharmacokinetic properties in a promising series of pyrrolopyrimidinone MARK inhibitors for the treatment of Alz …
Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors.
Katz JD, Haidle A, Childers KK, Zabierek AA, Jewell JP, Hou Y, Altman MD, Szewczak A, Chen D, Harsch A, Hayashi M, Warren L, Hutton M, Nuthall H, Su HP, Munshi S, Stanton MG, Davies IW, Munoz B, Northrup A. Katz JD, et al. Bioorg Med Chem Lett. 2017 Jan 1;27(1):114-120. doi: 10.1016/j.bmcl.2016.08.068. Epub 2016 Oct 22. Bioorg Med Chem Lett. 2017. PMID: 27816515
Information gleaned from ligand co-crystal structures allowed for rapid refinements in both MARK potency and kinase selectivity. These efforts allowed for the identification of a compound with properties suitable for use as an in vitro tool compound for validation studies …
Information gleaned from ligand co-crystal structures allowed for rapid refinements in both MARK potency and kinase selectivity. Thes …
The application of TreadMatch scans to aid the process of footwear mark comparison.
Reel S, Harris R, Reidy S, Chambers J. Reel S, et al. Sci Justice. 2022 Sep;62(5):530-539. doi: 10.1016/j.scijus.2022.07.011. Epub 2022 Aug 4. Sci Justice. 2022. PMID: 36336446
The resulting data were analysed to assess for agreement between TreadMatch scans and test marks using 95% Intraclass Correlation Coefficients (ICC) and 95% Bland-Altman plots of Limits of Agreement (LOA). Additionally, an intra-sample study using fifteen repeated measurem …
The resulting data were analysed to assess for agreement between TreadMatch scans and test marks using 95% Intraclass Correlation Coefficien …
Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties.
Sloman DL, Noucti N, Altman MD, Chen D, Mislak AC, Szewczak A, Hayashi M, Warren L, Dellovade T, Wu Z, Marcus J, Walker D, Su HP, Edavettal SC, Munshi S, Hutton M, Nuthall H, Stanton MG. Sloman DL, et al. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4362-6. doi: 10.1016/j.bmcl.2016.02.003. Epub 2016 Feb 6. Bioorg Med Chem Lett. 2016. PMID: 27491711
Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease. This manuscript outlines efforts to optimize a pyrazolopyrimidine series of MARK inhibitors by …
Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary ta …
A Photogrammetric Method for the Measurement of Three-Dimensional Cervical Range of Motion.
Li R, Jiang Q. Li R, et al. IEEE J Biomed Health Inform. 2022 Feb;26(2):685-695. doi: 10.1109/JBHI.2021.3089254. Epub 2022 Feb 4. IEEE J Biomed Health Inform. 2022. PMID: 34125694
Three smartphone cameras were controlled to simultaneously capture three-direction photographs of the subject wearing the special designed device with three mark lines. The obtained photographs were uploaded to a PC and the mark lines in each photograph were extract …
Three smartphone cameras were controlled to simultaneously capture three-direction photographs of the subject wearing the special designed d …
A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome.
Morin A, Thompson EE, Helling BA, Shorey-Kendrick LE, Faber P, Gebretsadik T, Bacharier LB, Kattan M, O'Connor GT, Rivera-Spoljaric K, Wood RA, Barnes KC, Mathias RA, Altman MC, Hansen K, McEvoy CT, Spindel ER, Hartert T, Jackson DJ, Gern JE, McKennan CG, Ober C; program collaborators for Environmental Influences on Child Health Outcomes and Children’s Respiratory and Environmental Workgroup. Morin A, et al. J Allergy Clin Immunol. 2023 Jun;151(6):1609-1621. doi: 10.1016/j.jaci.2022.12.828. Epub 2023 Feb 6. J Allergy Clin Immunol. 2023. PMID: 36754293 Free article.
BACKGROUND: DNA methylation of cytosines at cytosine-phosphate-guanine (CpG) dinucleotides (CpGs) is a widespread epigenetic mark, but genome-wide variation has been relatively unexplored due to the limited representation of variable CpGs on commercial high-throughput arra …
BACKGROUND: DNA methylation of cytosines at cytosine-phosphate-guanine (CpG) dinucleotides (CpGs) is a widespread epigenetic mark, bu …
124 results