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Showing results for mark harness
Your search for Mark Horness retrieved no results
Visualizing spatiotemporal dynamics of multicellular cell-cycle progression.
Sakaue-Sawano A, Kurokawa H, Morimura T, Hanyu A, Hama H, Osawa H, Kashiwagi S, Fukami K, Miyata T, Miyoshi H, Imamura T, Ogawa M, Masai H, Miyawaki A. Sakaue-Sawano A, et al. Cell. 2008 Feb 8;132(3):487-98. doi: 10.1016/j.cell.2007.12.033. Cell. 2008. PMID: 18267078 Free article.
The cell-cycle transition from G1 to S phase has been difficult to visualize. We have harnessed antiphase oscillating proteins that mark cell-cycle transitions in order to develop genetically encoded fluorescent probes for this purpose. ...
The cell-cycle transition from G1 to S phase has been difficult to visualize. We have harnessed antiphase oscillating proteins that …
The Promise of Adolescence: Realizing Opportunity for All Youth.
National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Division of Behavioral and Social Sciences and Education; Board on Children, Youth, and Families; Committee on the Neurobiological and Socio-behavioral Science of Adolescent Development and Its Applications; Backes EP, Bonnie RJ, editors. National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Division of Behavioral and Social Sciences and Education; Board on Children, Youth, and Families; Committee on the Neurobiological and Socio-behavioral Science of Adolescent Development and Its Applications, et al. Washington (DC): National Academies Press (US); 2019 May 16. Washington (DC): National Academies Press (US); 2019 May 16. PMID: 31449373 Free Books & Documents. Review.
These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to form relationships with peers and adults, and to explore one's developing identity. ...Because adolescents comprise nearly one-fourth of the …
These changes in brain structure, function, and connectivity mark adolescence as a period of opportunity to discover new vistas, to f …
Myeloid immunosuppression and immune checkpoints in the tumor microenvironment.
Nakamura K, Smyth MJ. Nakamura K, et al. Cell Mol Immunol. 2020 Jan;17(1):1-12. doi: 10.1038/s41423-019-0306-1. Epub 2019 Oct 14. Cell Mol Immunol. 2020. PMID: 31611651 Free PMC article. Review.
In this review, we discuss the complex crosstalk between cancer-related inflammation and immunosuppressive myeloid cells and possible therapeutic strategies to harness antitumor immune responses....
In this review, we discuss the complex crosstalk between cancer-related inflammation and immunosuppressive myeloid cells and possible therap …
The microcosmos of cancer.
Lujambio A, Lowe SW. Lujambio A, et al. Nature. 2012 Feb 15;482(7385):347-55. doi: 10.1038/nature10888. Nature. 2012. PMID: 22337054 Free PMC article. Review.
In the same way as certain key protein-coding genes, miRNAs can be deregulated in cancer, in which they can function as a group to mark differentiation states or individually as bona fide oncogenes or tumour suppressors. Importantly, miRNA biology can be harnessed e …
In the same way as certain key protein-coding genes, miRNAs can be deregulated in cancer, in which they can function as a group to mark …
Disrupting 3D printing of medicines with machine learning.
Elbadawi M, McCoubrey LE, Gavins FKH, Ong JJ, Goyanes A, Gaisford S, Basit AW. Elbadawi M, et al. Trends Pharmacol Sci. 2021 Sep;42(9):745-757. doi: 10.1016/j.tips.2021.06.002. Epub 2021 Jul 5. Trends Pharmacol Sci. 2021. PMID: 34238624 Review.
To make the vital leap to mainstream clinical practice and improve patient care, 3DP must harness modern technologies. Machine learning (ML), an influential branch of artificial intelligence, may be a key partner for 3DP. Together, 3DP and ML can utilise intelligence based …
To make the vital leap to mainstream clinical practice and improve patient care, 3DP must harness modern technologies. Machine learni …
Innovation at the Intersection of Alcohol and HIV Research.
van Heerden A, Tomlinson M, Skeen S, Parry C, Bryant K, Rotheram-Borus MJ. van Heerden A, et al. AIDS Behav. 2017 Nov;21(Suppl 2):274-278. doi: 10.1007/s10461-017-1926-z. AIDS Behav. 2017. PMID: 29043466 Free PMC article.
These approaches are (i) address the fact that the availability of new technology is unevenly distributed around the world, (ii) use technology to move beyond both paper and digital surveys, (iii) introduce a focus on advocacy and partnerships with large technology companies, (iv …
These approaches are (i) address the fact that the availability of new technology is unevenly distributed around the world, (ii) use technol …
EZH2 in normal and malignant hematopoiesis.
Lund K, Adams PD, Copland M. Lund K, et al. Leukemia. 2014 Jan;28(1):44-9. doi: 10.1038/leu.2013.288. Epub 2013 Oct 7. Leukemia. 2014. PMID: 24097338 Review.
The histone methyltransferase Enhancer of Zeste Homologue 2 (EZH2), a component of the polycomb group complex, is vital for stem cell development, including hematopoiesis. Its primary function, to deposit the histone mark H3K27me3, promotes transcriptional repression. The …
The histone methyltransferase Enhancer of Zeste Homologue 2 (EZH2), a component of the polycomb group complex, is vital for stem cell develo …
Harnessing the effects of endurance exercise to optimize cognitive health: Fundamental insights from Dr. Mark P. Mattson.
Jachim SK, Sakamoto AE, Zhang X, Pearsall VM, Schafer MJ, LeBrasseur NK. Jachim SK, et al. Ageing Res Rev. 2020 Dec;64:101147. doi: 10.1016/j.arr.2020.101147. Epub 2020 Aug 16. Ageing Res Rev. 2020. PMID: 32814127 Free PMC article. Review.
Dr. Mark Mattson has had a highly productive and impactful tenure as a neuroscientist at the Intramural Research Program of the National Institute on Aging. ...
Dr. Mark Mattson has had a highly productive and impactful tenure as a neuroscientist at the Intramural Research Program of the Natio …
Harnessing the immune system in acute myeloid leukaemia.
Austin R, Smyth MJ, Lane SW. Austin R, et al. Crit Rev Oncol Hematol. 2016 Jul;103:62-77. doi: 10.1016/j.critrevonc.2016.04.020. Epub 2016 May 11. Crit Rev Oncol Hematol. 2016. PMID: 27247119 Review.
The deeper self: an expanded view of consciousness.
Paulson S, Hustvedt S, Solms M, Shamdasani S. Paulson S, et al. Ann N Y Acad Sci. 2017 Oct;1406(1):46-63. doi: 10.1111/nyas.13403. Epub 2017 Jun 22. Ann N Y Acad Sci. 2017. PMID: 28640959 Review.
If the unconscious is a source of intuitive and creative inspiration, how might a more expansive understanding of consciousness help us to flourish? How can we harness the intuitive parts of ourselves to think "outside the box," transcending the limitations of preconceived …
If the unconscious is a source of intuitive and creative inspiration, how might a more expansive understanding of consciousness help us to f …
106 results