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Synthesis and Decontamination Effect on Chemical and Biological Agents of Benzoxonium-Like Salts.
Markova A, Hympanova M, Matula M, Prchal L, Sleha R, Benkova M, Pulkrabkova L, Soukup O, Krocova Z, Jun D, Marek J. Markova A, et al. Toxics. 2021 Sep 15;9(9):222. doi: 10.3390/toxics9090222. Toxics. 2021. PMID: 34564373 Free PMC article.
Benzoxonium chloride belongs to the group of quaternary ammonium salts, which have been widely used for decades as disinfectants because of their high efficacy, low toxicity, and thermal stability. In this study, we have prepared the C(10)-C(18) set of benzoxonium-like sal …
Benzoxonium chloride belongs to the group of quaternary ammonium salts, which have been widely used for decades as disinfectants because of …
IgE blockade with omalizumab reduces pruritus related to immune checkpoint inhibitors and anti-HER2 therapies.
Barrios DM, Phillips GS, Geisler AN, Trelles SR, Markova A, Noor SJ, Quigley EA, Haliasos HC, Moy AP, Schram AM, Bromberg J, Funt SA, Voss MH, Drilon A, Hellmann MD, Comen EA, Narala S, Patel AB, Wetzel M, Jung JY, Leung DYM, Lacouture ME. Barrios DM, et al. Ann Oncol. 2021 Jun;32(6):736-745. doi: 10.1016/j.annonc.2021.02.016. Epub 2021 Mar 3. Ann Oncol. 2021. PMID: 33667669 Free PMC article.

The proportion of patients receiving oral corticosteroids as supportive treatment for management of paCAEs decreased with IgE blockade, from 50% to 9% (P < 0.001). Ten of 32 (31%) patients had interruption of oncologic therapy due to skin toxicity; four of six (6

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The proportion of patients receiving oral corticosteroids as supportive treatment for management of paCAEs decreased with IgE blockade, from …
Intensified treatment of patients with early stage, unfavourable Hodgkin lymphoma: long-term follow-up of a randomised, international phase 3 trial of the German Hodgkin Study Group (GHSG HD14).
Gillessen S, Plütschow A, Fuchs M, Markova J, Greil R, Topp MS, Meissner J, Zijlstra JM, Eichenauer DA, Bröckelmann PJ, Diehl V, Borchmann P, Engert A, von Tresckow B. Gillessen S, et al. Lancet Haematol. 2021 Apr;8(4):e278-e288. doi: 10.1016/S2352-3026(21)00029-6. Lancet Haematol. 2021. PMID: 33770483 Clinical Trial.
In this prespecified long-term follow-up analysis, we aimed to evaluate the secondary endpoints progression-free survival, overall survival, and long-term toxicity. To this end, we did a descriptive intention-to-treat analysis of all qualified HD14 patients and on the pred …
In this prespecified long-term follow-up analysis, we aimed to evaluate the secondary endpoints progression-free survival, overall survival, …