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Leoligin, the major lignan from Edelweiss, activates cholesteryl ester transfer protein.
Duwensee K, Schwaiger S, Tancevski I, Eller K, van Eck M, Markt P, Linder T, Stanzl U, Ritsch A, Patsch JR, Schuster D, Stuppner H, Bernhard D, Eller P. Duwensee K, et al. Among authors: markt p. Atherosclerosis. 2011 Nov;219(1):109-15. doi: 10.1016/j.atherosclerosis.2011.07.023. Epub 2011 Jul 21. Atherosclerosis. 2011. PMID: 21820657 Free PMC article.
Pharmacophore modeling and parallel screening for PPAR ligands.
Markt P, Schuster D, Kirchmair J, Laggner C, Langer T. Markt P, et al. J Comput Aided Mol Des. 2007 Oct-Nov;21(10-11):575-90. doi: 10.1007/s10822-007-9140-0. Epub 2007 Oct 25. J Comput Aided Mol Des. 2007. PMID: 17960326
Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma.
Fakhrudin N, Ladurner A, Atanasov AG, Heiss EH, Baumgartner L, Markt P, Schuster D, Ellmerer EP, Wolber G, Rollinger JM, Stuppner H, Dirsch VM. Fakhrudin N, et al. Among authors: markt p. Mol Pharmacol. 2010 Apr;77(4):559-66. doi: 10.1124/mol.109.062141. Epub 2010 Jan 11. Mol Pharmacol. 2010. PMID: 20064974 Free PMC article.
Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques.
Noha SM, Atanasov AG, Schuster D, Markt P, Fakhrudin N, Heiss EH, Schrammel O, Rollinger JM, Stuppner H, Dirsch VM, Wolber G. Noha SM, et al. Among authors: markt p. Bioorg Med Chem Lett. 2011 Jan 1;21(1):577-83. doi: 10.1016/j.bmcl.2010.10.051. Epub 2010 Oct 20. Bioorg Med Chem Lett. 2011. PMID: 21078555 Free PMC article.
Virtual screening against obesity.
Markt P, Herdlinger S, Schuster D. Markt P, et al. Curr Med Chem. 2011;18(14):2158-73. doi: 10.2174/092986711795656162. Curr Med Chem. 2011. PMID: 21517763 Review.
33 results