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Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3.
Nature. 2022 Apr;604(7904):184-189. doi: 10.1038/s41586-022-04467-w. Epub 2022 Feb 3.
Nature. 2022.
PMID: 35114687
Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly.
Marleaux M, Anand K, Latz E, Geyer M.
Marleaux M, et al.
FEBS Lett. 2020 Aug;594(15):2383-2395. doi: 10.1002/1873-3468.13865. Epub 2020 Jul 6.
FEBS Lett. 2020.
PMID: 32542665
Free article.
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Development of Fluorescent and Biotin Probes Targeting NLRP3.
Keuler T, Gatterdam K, Akbal A, Lovotti M, Marleaux M, Geyer M, Latz E, Gütschow M.
Keuler T, et al. Among authors: marleaux m.
Front Chem. 2021 Apr 22;9:642273. doi: 10.3389/fchem.2021.642273. eCollection 2021.
Front Chem. 2021.
PMID: 33996748
Free PMC article.
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Structure-Stability Relationship of NLRP3 Inflammasome-Inhibiting Sulfonylureas.
Keuler T, Ferber D, Marleaux M, Geyer M, Gütschow M.
Keuler T, et al. Among authors: marleaux m.
ACS Omega. 2022 Feb 23;7(9):8158-8162. doi: 10.1021/acsomega.2c00125. eCollection 2022 Mar 8.
ACS Omega. 2022.
PMID: 35284735
Free PMC article.
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The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screening.
Hartman G, Humphries P, Hughes R, Ho A, Montgomery R, Deshpande A, Mahanta M, Tronnes S, Cowdin S, He X, Liu F, Zhang L, Liu C, Dou D, Li J, Spasic A, Coll R, Marleaux M, Hochheiser IV, Geyer M, Rubin P, Fortney K, Wilhelmsen K.
Hartman G, et al. Among authors: marleaux m.
Bioorg Med Chem Lett. 2024 Apr 1;102:129675. doi: 10.1016/j.bmcl.2024.129675. Epub 2024 Feb 28.
Bioorg Med Chem Lett. 2024.
PMID: 38417632
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