Martinez Molina D - Search Results

1

Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase.

Martinez Molina D, Wetterholm A, Kohl A, McCarthy AA, Niegowski D, Ohlson E, Hammarberg T, Eshaghi S, Haeggström JZ, Nordlund P. Martinez Molina D, et al. Nature. 2007 Aug 2;448(7153):613-6. doi: 10.1038/nature06009. Epub 2007 Jul 15. Nature. 2007. PMID: 17632546

2

Crystal structure of a divalent metal ion transporter CorA at 2.9 angstrom resolution.

Eshaghi S, Niegowski D, Kohl A, Martinez Molina D, Lesley SA, Nordlund P. Eshaghi S, et al. Among authors: martinez molina d. Science. 2006 Jul 21;313(5785):354-7. doi: 10.1126/science.1127121. Science. 2006. PMID: 16857941

3

Engineering membrane protein overproduction in Escherichia coli.

Martinez Molina D, Cornvik T, Eshaghi S, Haeggström JZ, Nordlund P, Sabet MI. Martinez Molina D, et al. Protein Sci. 2008 Apr;17(4):673-80. doi: 10.1110/ps.073242508. Epub 2008 Feb 27. Protein Sci. 2008. PMID: 18305199 Free PMC article.

4

High-level expression, purification, and crystallization of recombinant rat leukotriene C(4) synthase from the yeast Pichia pastoris.

Wetterholm A, Martinez Molina D, Nordlund P, Eshaghi S, Haeggström JZ. Wetterholm A, et al. Among authors: martinez molina d. Protein Expr Purif. 2008 Jul;60(1):1-6. doi: 10.1016/j.pep.2008.03.005. Epub 2008 Mar 23. Protein Expr Purif. 2008. PMID: 18440824

5

Catalysis within the lipid bilayer-structure and mechanism of the MAPEG family of integral membrane proteins.

Martinez Molina D, Eshaghi S, Nordlund P. Martinez Molina D, et al. Curr Opin Struct Biol. 2008 Aug;18(4):442-9. doi: 10.1016/j.sbi.2008.04.005. Epub 2008 Jun 12. Curr Opin Struct Biol. 2008. PMID: 18550357

6

Expression and purification of the recombinant membrane protein YidC: a case study for increased stability and solubility.

Martinez Molina D, Lundbäck AK, Niegowski D, Eshaghi S. Martinez Molina D, et al. Protein Expr Purif. 2008 Nov;62(1):49-52. doi: 10.1016/j.pep.2008.05.011. Epub 2008 May 28. Protein Expr Purif. 2008. PMID: 18586516

7

Arginine 104 is a key catalytic residue in leukotriene C4 synthase.

Rinaldo-Matthis A, Wetterholm A, Martinez Molina D, Holm J, Niegowski D, Ohlson E, Nordlund P, Morgenstern R, Haeggström JZ. Rinaldo-Matthis A, et al. Among authors: martinez molina d. J Biol Chem. 2010 Dec 24;285(52):40771-6. doi: 10.1074/jbc.M110.105940. Epub 2010 Oct 27. J Biol Chem. 2010. PMID: 20980252 Free PMC article.

8

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

Martinez Molina D, Jafari R, Ignatushchenko M, Seki T, Larsson EA, Dan C, Sreekumar L, Cao Y, Nordlund P. Martinez Molina D, et al. Science. 2013 Jul 5;341(6141):84-7. doi: 10.1126/science.1233606. Science. 2013. PMID: 23828940

9

The cellular thermal shift assay for evaluating drug target interactions in cells.

Jafari R, Almqvist H, Axelsson H, Ignatushchenko M, Lundbäck T, Nordlund P, Martinez Molina D. Jafari R, et al. Among authors: martinez molina d. Nat Protoc. 2014 Sep;9(9):2100-22. doi: 10.1038/nprot.2014.138. Epub 2014 Aug 7. Nat Protoc. 2014. PMID: 25101824

10

Tracking cancer drugs in living cells by thermal profiling of the proteome.

Savitski MM, Reinhard FB, Franken H, Werner T, Savitski MF, Eberhard D, Martinez Molina D, Jafari R, Dovega RB, Klaeger S, Kuster B, Nordlund P, Bantscheff M, Drewes G. Savitski MM, et al. Among authors: martinez molina d. Science. 2014 Oct 3;346(6205):1255784. doi: 10.1126/science.1255784. Epub 2014 Oct 2. Science. 2014. PMID: 25278616

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