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The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activity.
Leoh LS, van Heertum B, De Rijck J, Filippova M, Rios-Colon L, Basu A, Martinez SR, Tungteakkhun SS, Filippov V, Christ F, De Leon M, Debyser Z, Casiano CA. Leoh LS, et al. Among authors: martinez sr. Mol Cancer Res. 2012 Mar;10(3):378-91. doi: 10.1158/1541-7786.MCR-11-0314. Epub 2012 Jan 24. Mol Cancer Res. 2012. PMID: 22275515 Free PMC article.
LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer.
Basu A, Cajigas-Du Ross CK, Rios-Colon L, Mediavilla-Varela M, Daniels-Wells TR, Leoh LS, Rojas H, Banerjee H, Martinez SR, Acevedo-Martinez S, Casiano CA. Basu A, et al. Among authors: martinez sr. PLoS One. 2016 Jan 15;11(1):e0146549. doi: 10.1371/journal.pone.0146549. eCollection 2016. PLoS One. 2016. PMID: 26771192 Free PMC article.
RNA sequencing reveals upregulation of a transcriptomic program associated with stemness in metastatic prostate cancer cells selected for taxane resistance.
Cajigas-Du Ross CK, Martinez SR, Woods-Burnham L, Durán AM, Roy S, Basu A, Ramirez JA, Ortiz-Hernández GL, Ríos-Colón L, Chirshev E, Sanchez-Hernandez ES, Soto U, Greco C, Boucheix C, Chen X, Unternaehrer J, Wang C, Casiano CA. Cajigas-Du Ross CK, et al. Among authors: martinez sr. Oncotarget. 2018 Jul 13;9(54):30363-30384. doi: 10.18632/oncotarget.25744. eCollection 2018 Jul 13. Oncotarget. 2018. PMID: 30100995 Free PMC article.
Glucocorticoids Induce Stress Oncoproteins Associated with Therapy-Resistance in African American and European American Prostate Cancer Cells.
Woods-Burnham L, Cajigas-Du Ross CK, Love A, Basu A, Sanchez-Hernandez ES, Martinez SR, Ortiz-Hernández GL, Stiel L, Durán AM, Wilson C, Montgomery S, Roy S, Casiano CA. Woods-Burnham L, et al. Among authors: martinez sr. Sci Rep. 2018 Oct 10;8(1):15063. doi: 10.1038/s41598-018-33150-2. Sci Rep. 2018. PMID: 30305646 Free PMC article.
The LEDGF/p75 Integrase Binding Domain Interactome Contributes to the Survival, Clonogenicity, and Tumorsphere Formation of Docetaxel-Resistant Prostate Cancer Cells.
Ortiz-Hernandez GL, Sanchez-Hernandez ES, Ochoa PT, Elix CC, Alkashgari HR, McMullen JRW, Soto U, Martinez SR, Diaz Osterman CJ, Mahler M, Roy S, Casiano CA. Ortiz-Hernandez GL, et al. Among authors: martinez sr. Cells. 2021 Oct 12;10(10):2723. doi: 10.3390/cells10102723. Cells. 2021. PMID: 34685704 Free PMC article.
Psychosocial Stress, Glucocorticoid Signaling, and Prostate Cancer Health Disparities in African American Men.
Woods-Burnham L, Stiel L, Martinez SR, Sanchez-Hernandez ES, Ruckle HC, Almaguel FG, Stern MC, Roberts LR, Williams DR, Montgomery S, Casiano CA. Woods-Burnham L, et al. Among authors: martinez sr. Cancer Health Disparities. 2020;4:https://companyofscientists.com/index.php/chd/article/view/169/188. Cancer Health Disparities. 2020. PMID: 35252767 Free PMC article.
130 results