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Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition.
Prado VF, Martins-Silva C, de Castro BM, Lima RF, Barros DM, Amaral E, Ramsey AJ, Sotnikova TD, Ramirez MR, Kim HG, Rossato JI, Koenen J, Quan H, Cota VR, Moraes MF, Gomez MV, Guatimosim C, Wetsel WC, Kushmerick C, Pereira GS, Gainetdinov RR, Izquierdo I, Caron MG, Prado MA. Prado VF, et al. Neuron. 2006 Sep 7;51(5):601-12. doi: 10.1016/j.neuron.2006.08.005. Neuron. 2006. PMID: 16950158 Free article.
Reduced expression of the vesicular acetylcholine transporter causes learning deficits in mice.
de Castro BM, Pereira GS, Magalhães V, Rossato JI, De Jaeger X, Martins-Silva C, Leles B, Lima P, Gomez MV, Gainetdinov RR, Caron MG, Izquierdo I, Cammarota M, Prado VF, Prado MA. de Castro BM, et al. Genes Brain Behav. 2009 Feb;8(1):23-35. doi: 10.1111/j.1601-183X.2008.00439.x. Epub 2008 Sep 6. Genes Brain Behav. 2009. PMID: 18778400 Free article.
A rat homologue of CED-6 is expressed in neurons and interacts with clathrin.
Martins-Silva C, Ferreira LT, Cyr M, Koenen J, Fernandes DR, Carvalho NR, Ribeiro CB, Marion S, Chavez-Olortegui C, Prado MA, Prado VF. Martins-Silva C, et al. Brain Res. 2006 Nov 13;1119(1):1-12. doi: 10.1016/j.brainres.2006.08.064. Epub 2006 Sep 26. Brain Res. 2006. PMID: 17007823
The vesicular acetylcholine transporter is required for neuromuscular development and function.
de Castro BM, De Jaeger X, Martins-Silva C, Lima RD, Amaral E, Menezes C, Lima P, Neves CM, Pires RG, Gould TW, Welch I, Kushmerick C, Guatimosim C, Izquierdo I, Cammarota M, Rylett RJ, Gomez MV, Caron MG, Oppenheim RW, Prado MA, Prado VF. de Castro BM, et al. Mol Cell Biol. 2009 Oct;29(19):5238-50. doi: 10.1128/MCB.00245-09. Epub 2009 Jul 27. Mol Cell Biol. 2009. PMID: 19635813 Free PMC article.
Downregulation of the cAMP/PKA pathway in PC12 cells overexpressing NCS-1.
Souza BR, Torres KC, Miranda DM, Motta BS, Caetano FS, Rosa DV, Souza RP, Giovani A Jr, Carneiro DS, Guimarães MM, Martins-Silva C, Reis HJ, Gomez MV, Jeromin A, Romano-Silva MA. Souza BR, et al. Cell Mol Neurobiol. 2011 Jan;31(1):135-43. doi: 10.1007/s10571-010-9562-4. Epub 2010 Sep 14. Cell Mol Neurobiol. 2011. PMID: 20838877
41 results