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Macitentan reverses early obstructive pulmonary vasculopathy in rats: early intervention in overcoming the survivin-mediated resistance to apoptosis.
Shinohara T, Sawada H, Otsuki S, Yodoya N, Kato T, Ohashi H, Zhang E, Saitoh S, Shimpo H, Maruyama K, Komada Y, Mitani Y. Shinohara T, et al. Among authors: maruyama k. Am J Physiol Lung Cell Mol Physiol. 2015 Mar 15;308(6):L523-38. doi: 10.1152/ajplung.00129.2014. Epub 2014 Dec 24. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25539851 Free article.
The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension.
Morikawa M, Mitani Y, Holmborn K, Kato T, Koinuma D, Maruyama J, Vasilaki E, Sawada H, Kobayashi M, Ozawa T, Morishita Y, Bessho Y, Maeda S, Ledin J, Aburatani H, Kageyama R, Maruyama K, Heldin CH, Miyazono K. Morikawa M, et al. Among authors: maruyama k, maruyama j. Sci Signal. 2019 Nov 12;12(607):eaay4430. doi: 10.1126/scisignal.aay4430. Sci Signal. 2019. PMID: 31719172 Free PMC article.
A non-selective endothelin receptor antagonist bosentan modulates kinetics of bone marrow-derived cells in ameliorating pulmonary hypertension in mice.
Kato T, Mitani Y, Masuya M, Maruyama J, Sawada H, Ohashi H, Ikeyama Y, Otsuki S, Yodoya N, Shinohara T, Miyata E, Zhang E, Katayama N, Shimpo H, Maruyama K, Komada Y, Hirayama M. Kato T, et al. Among authors: maruyama k, maruyama j. Pulm Circ. 2020 May 14;10(2):2045894020919355. doi: 10.1177/2045894020919355. eCollection 2020 Apr-Jun. Pulm Circ. 2020. PMID: 32489640 Free PMC article.
CRISPR-mediated Bmpr2 point mutation exacerbates late pulmonary vasculopathy and reduces survival in rats with experimental pulmonary hypertension.
Kabwe JC, Sawada H, Mitani Y, Oshita H, Tsuboya N, Zhang E, Maruyama J, Miyasaka Y, Ko H, Oya K, Ito H, Yodoya N, Otsuki S, Ohashi H, Okamoto R, Dohi K, Nishimura Y, Mashimo T, Hirayama M, Maruyama K. Kabwe JC, et al. Among authors: maruyama k, maruyama j. Respir Res. 2022 Apr 8;23(1):87. doi: 10.1186/s12931-022-02005-w. Respir Res. 2022. PMID: 35395852 Free PMC article.
2,846 results