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Year Number of Results
1975 1
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1999 9
2000 13
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2002 10
2003 7
2004 14
2005 21
2006 27
2007 35
2008 31
2009 31
2010 28
2011 35
2012 48
2013 44
2014 35
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Page 1
MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence.
Elhadad S, Redmond D, Huang J, Tan A, Laurence J. Elhadad S, et al. Clin Exp Immunol. 2023 Jul 21;213(2):252-264. doi: 10.1093/cei/uxad055. Clin Exp Immunol. 2023. PMID: 37191586
We hypothesized that mannose-binding lectin-associated serine protease 2 (MASP2), principal activator of the lectin complement system, is involved in the microvascular endothelial cell (MVEC) injury characteristic of TA-TMA through pathways that are susceptible to suppress …
We hypothesized that mannose-binding lectin-associated serine protease 2 (MASP2), principal activator of the lectin complement system …
Association of MASP2 levels and MASP2 gene polymorphisms with systemic lupus erythematosus.
Xu WD, Liu XY, Su LC, Huang AF. Xu WD, et al. J Cell Mol Med. 2020 Sep;24(18):10432-10443. doi: 10.1111/jcmm.15656. Epub 2020 Jul 17. J Cell Mol Med. 2020. PMID: 32677764 Free PMC article.
Receiver operating characteristic (ROC) curve analysis determined the discriminatory capacity for serum MASP2. PCR methods tested the association of MASP2 gene polymorphisms (rs7548659, rs17409276, rs2273346, rs1782455 and rs6695096) and SLE risk. ...Interestingly, …
Receiver operating characteristic (ROC) curve analysis determined the discriminatory capacity for serum MASP2. PCR methods tested the …
Impact of MASP2 gene polymorphism and gene-tea drinking interaction on susceptibility to tuberculosis.
Li Z, Wang M, Zhong H, Huang X, Wu X, Zhang X, Wang J, Deng J, Chen M, Chen L, Tan H. Li Z, et al. Sci Rep. 2021 Mar 22;11(1):6544. doi: 10.1038/s41598-021-86129-x. Sci Rep. 2021. PMID: 33753877 Free PMC article.
The gene-tea drinking interactions were analyzed by the additive model of marginal structural linear odds models. Both genotype AC + AA at rs12711521 of MASP2 genes and genotype GT + GG at rs7548659 of MASP2 genes were more prevalent in the TB patient group than the …
The gene-tea drinking interactions were analyzed by the additive model of marginal structural linear odds models. Both genotype AC + AA at r …
C5b-9 and MASP2 deposition in skin and bone marrow microvasculature characterize hematopoietic stem cell transplant-associated thrombotic microangiopathy.
Elhadad S, Chadburn A, Magro C, Van Besien K, Roberson EDO, Atkinson JP, Terry H, Greenberg J, Reid W, Chapin J, Copertino D, Geramfard S, Rodriguez LB, Orfali N, Gerghis U, Shore T, Mayer S, Ahamed J, Laurence J. Elhadad S, et al. Bone Marrow Transplant. 2022 Sep;57(9):1445-1447. doi: 10.1038/s41409-022-01723-5. Epub 2022 Jun 4. Bone Marrow Transplant. 2022. PMID: 35661836 No abstract available.
MASP2 haplotypes are associated with high risk of cardiomyopathy in chronic Chagas disease.
Boldt AB, Luz PR, Messias-Reason IJ. Boldt AB, et al. Clin Immunol. 2011 Jul;140(1):63-70. doi: 10.1016/j.clim.2011.03.008. Epub 2011 Mar 23. Clin Immunol. 2011. PMID: 21489885
Mannose-binding lectin (MBL) initiates complement on Trypanosoma cruzi through the MBL-associated serine protease 2 (MASP2). We haplotyped six MASP2 polymorphisms in 208 chronic chagasic patients, being 81 indeterminate and 123 symptomatic (76 with cardiac, 19 with …
Mannose-binding lectin (MBL) initiates complement on Trypanosoma cruzi through the MBL-associated serine protease 2 (MASP2). We haplo …
MASP2 gene polymorphism is associated with susceptibility to hepatitis C virus infection.
Tulio S, Faucz FR, Werneck RI, Olandoski M, Alexandre RB, Boldt AB, Pedroso ML, de Messias-Reason IJ. Tulio S, et al. Hum Immunol. 2011 Oct;72(10):912-5. doi: 10.1016/j.humimm.2011.06.016. Epub 2011 Jul 31. Hum Immunol. 2011. PMID: 21843573 Free PMC article.
Hepatitis C virus (HCV) has become a major public health issue and is prevalent in most countries. We examined several MASP2 functional polymorphisms in 104 Brazilian patients with moderate and severe chronic hepatitis C using the primers set to amplify the region encoding …
Hepatitis C virus (HCV) has become a major public health issue and is prevalent in most countries. We examined several MASP2 function …
Effects of MASP2 haplotypes and MASP-2 levels in hepatitis C-infected patients.
Silva AA, Catarino SJ, Boldt ABW, Pedroso MLA, Beltrame MH, Messias-Reason IJ. Silva AA, et al. Int J Immunogenet. 2018 Jun;45(3):118-127. doi: 10.1111/iji.12371. Epub 2018 Apr 19. Int J Immunogenet. 2018. PMID: 29675993
The haplotype block MASP2*ARDP was associated with protection against HCV infection (OR = 0.49, p = .044) and lower MASP-2 levels in controls (p = .021), while haplotype block AGTDVRC was significantly increased in patients (OR = 7.58, p = .003). ...MASP-2 levels decrease …
The haplotype block MASP2*ARDP was associated with protection against HCV infection (OR = 0.49, p = .044) and lower MASP-2 levels in …
MBL2 and MASP2 gene polymorphisms in patients with hepatocellular carcinoma.
Segat L, Fabris A, Padovan L, Milanese M, Pirulli D, Lupo F, Salizzoni M, Amoroso A, Crovella S. Segat L, et al. J Viral Hepat. 2008 May;15(5):387-91. doi: 10.1111/j.1365-2893.2007.00965.x. J Viral Hepat. 2008. PMID: 18221301
Mannan-binding lectin (MBL) is a collectin that can act directly as opsonine or activate MBL-associated serine proteases (MASPs) thus initiating the antibody-independent pathway of the complement system. In our study, we analysed two MBL2 and MASP2 functional polymorphisms …
Mannan-binding lectin (MBL) is a collectin that can act directly as opsonine or activate MBL-associated serine proteases (MASPs) thus initia …
Anti-Coagulant and Antimicrobial Recombinant Heparin-Binding Major Ampullate Spidroin 2 (MaSp2) Silk Protein.
Mulinti P, Diekjürgen D, Kurtzeborn K, Balasubramanian N, Stafslien SJ, Grainger DW, Brooks AE. Mulinti P, et al. Bioengineering (Basel). 2022 Jan 19;9(2):46. doi: 10.3390/bioengineering9020046. Bioengineering (Basel). 2022. PMID: 35200400 Free PMC article.
In this study, a small basic peptide, (ARKKAAKA) known to both bind heparin and mimic an antimicrobial peptide, was genetically linked to a protease-resistant, mechanically robust silk-like peptide, MaSp2. Purified fusion proteins (four silk domains and four heparin-bindin …
In this study, a small basic peptide, (ARKKAAKA) known to both bind heparin and mimic an antimicrobial peptide, was genetically linked to a …
624 results