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Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice.
Grant AD, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P, Materazzi S, Altier C, Cenac N, Zamponi GW, Bautista-Cruz F, Lopez CB, Joseph EK, Levine JD, Liedtke W, Vanner S, Vergnolle N, Geppetti P, Bunnett NW. Grant AD, et al. Among authors: materazzi s. J Physiol. 2007 Feb 1;578(Pt 3):715-33. doi: 10.1113/jphysiol.2006.121111. Epub 2006 Nov 23. J Physiol. 2007. PMID: 17124270 Free PMC article.
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, Andrè E, Patacchini R, Cottrell GS, Gatti R, Basbaum AI, Bunnett NW, Julius D, Geppetti P. Trevisani M, et al. Among authors: materazzi s. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13519-24. doi: 10.1073/pnas.0705923104. Epub 2007 Aug 7. Proc Natl Acad Sci U S A. 2007. PMID: 17684094 Free PMC article.
The concept of neurogenic inflammation.
Geppetti P, Nassini R, Materazzi S, Benemei S. Geppetti P, et al. Among authors: materazzi s. BJU Int. 2008 Mar;101 Suppl 3:2-6. doi: 10.1111/j.1464-410X.2008.07493.x. BJU Int. 2008. PMID: 18307678 Review.
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Andrè E, Campi B, Materazzi S, Trevisani M, Amadesi S, Massi D, Creminon C, Vaksman N, Nassini R, Civelli M, Baraldi PG, Poole DP, Bunnett NW, Geppetti P, Patacchini R. Andrè E, et al. Among authors: materazzi s. J Clin Invest. 2008 Jul;118(7):2574-82. doi: 10.1172/JCI34886. J Clin Invest. 2008. PMID: 18568077 Free PMC article.
The TGR5 receptor mediates bile acid-induced itch and analgesia.
Alemi F, Kwon E, Poole DP, Lieu T, Lyo V, Cattaruzza F, Cevikbas F, Steinhoff M, Nassini R, Materazzi S, Guerrero-Alba R, Valdez-Morales E, Cottrell GS, Schoonjans K, Geppetti P, Vanner SJ, Bunnett NW, Corvera CU. Alemi F, et al. Among authors: materazzi s. J Clin Invest. 2013 Apr;123(4):1513-30. doi: 10.1172/JCI64551. Epub 2013 Mar 25. J Clin Invest. 2013. PMID: 23524965 Free PMC article.
The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice.
Lieu T, Jayaweera G, Zhao P, Poole DP, Jensen D, Grace M, McIntyre P, Bron R, Wilson YM, Krappitz M, Haerteis S, Korbmacher C, Steinhoff MS, Nassini R, Materazzi S, Geppetti P, Corvera CU, Bunnett NW. Lieu T, et al. Among authors: materazzi s. Gastroenterology. 2014 Dec;147(6):1417-28. doi: 10.1053/j.gastro.2014.08.042. Epub 2014 Sep 3. Gastroenterology. 2014. PMID: 25194674 Free PMC article.
A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation.
Vergnolle N, Cenac N, Altier C, Cellars L, Chapman K, Zamponi GW, Materazzi S, Nassini R, Liedtke W, Cattaruzza F, Grady EF, Geppetti P, Bunnett NW. Vergnolle N, et al. Among authors: materazzi s. Br J Pharmacol. 2010 Mar;159(5):1161-73. doi: 10.1111/j.1476-5381.2009.00590.x. Epub 2010 Feb 5. Br J Pharmacol. 2010. PMID: 20136846 Free PMC article.
128 results