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BYON4228 is a pan-allelic antagonistic SIRPα antibody that potentiates destruction of antibody-opsonized tumor cells and lacks binding to SIRPγ on T cells.
van Helden MJ, Zwarthoff SA, Arends RJ, Reinieren-Beeren IMJ, Paradé MCBC, Driessen-Engels L, de Laat-Arts K, Damming D, Santegoeds-Lenssen EWH, van Kuppeveld DWJ, Lodewijks I, Olsman H, Matlung HL, Franke K, Mattaar-Hepp E, Stokman MEM, de Wit B, Glaudemans DHRF, van Wijk DEJW, Joosten-Stoffels L, Schouten J, Boersema PJ, van der Vleuten M, Sanderink JWH, Kappers WA, van den Dobbelsteen D, Timmers M, Ubink R, Rouwendal GJA, Verheijden G, van der Lee MMC, Dokter WHA, van den Berg TK. van Helden MJ, et al. Among authors: matlung hl. J Immunother Cancer. 2023 Apr;11(4):e006567. doi: 10.1136/jitc-2022-006567. J Immunother Cancer. 2023. PMID: 37068796 Free PMC article.
On the mechanism of CD47 targeting in cancer.
Zhao XW, Matlung HL, Kuijpers TW, van den Berg TK. Zhao XW, et al. Among authors: matlung hl. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):E2843; author reply E2844-5. doi: 10.1073/pnas.1209265109. Epub 2012 Aug 24. Proc Natl Acad Sci U S A. 2012. PMID: 22923695 Free PMC article. No abstract available.
Regulation of Phagocyte Migration by Signal Regulatory Protein-Alpha Signaling.
Alvarez-Zarate J, Matlung HL, Matozaki T, Kuijpers TW, Maridonneau-Parini I, van den Berg TK. Alvarez-Zarate J, et al. Among authors: matlung hl. PLoS One. 2015 Jun 9;10(6):e0127178. doi: 10.1371/journal.pone.0127178. eCollection 2015. PLoS One. 2015. PMID: 26057870 Free PMC article.
Immunoreceptors on neutrophils.
van Rees DJ, Szilagyi K, Kuijpers TW, Matlung HL, van den Berg TK. van Rees DJ, et al. Among authors: matlung hl. Semin Immunol. 2016 Apr;28(2):94-108. doi: 10.1016/j.smim.2016.02.004. Epub 2016 Mar 11. Semin Immunol. 2016. PMID: 26976825 Free PMC article. Review.
Neutrophils in cancer.
Treffers LW, Hiemstra IH, Kuijpers TW, van den Berg TK, Matlung HL. Treffers LW, et al. Among authors: matlung hl. Immunol Rev. 2016 Sep;273(1):312-28. doi: 10.1111/imr.12444. Immunol Rev. 2016. PMID: 27558343 Review.
Immune checkpoint blockade: Which switches to hit and how much?
Matlung HL, Szilagyi K, Kuijpers TW, van Lier RAW, van den Berg TK. Matlung HL, et al. Immunol Lett. 2016 Dec;180:73-74. doi: 10.1016/j.imlet.2016.08.014. Epub 2016 Sep 20. Immunol Lett. 2016. PMID: 27662791 No abstract available.
Genetic variation of human neutrophil Fcγ receptors and SIRPα in antibody-dependent cellular cytotoxicity towards cancer cells.
Treffers LW, Zhao XW, van der Heijden J, Nagelkerke SQ, van Rees DJ, Gonzalez P, Geissler J, Verkuijlen P, van Houdt M, de Boer M, Kuijpers TW, van den Berg TK, Matlung HL. Treffers LW, et al. Among authors: matlung hl. Eur J Immunol. 2018 Feb;48(2):344-354. doi: 10.1002/eji.201747215. Epub 2017 Nov 2. Eur J Immunol. 2018. PMID: 28952147 Free article.
Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.
Matlung HL, Babes L, Zhao XW, van Houdt M, Treffers LW, van Rees DJ, Franke K, Schornagel K, Verkuijlen P, Janssen H, Halonen P, Lieftink C, Beijersbergen RL, Leusen JHW, Boelens JJ, Kuhnle I, van der Werff Ten Bosch J, Seeger K, Rutella S, Pagliara D, Matozaki T, Suzuki E, Menke-van der Houven van Oordt CW, van Bruggen R, Roos D, van Lier RAW, Kuijpers TW, Kubes P, van den Berg TK. Matlung HL, et al. Cell Rep. 2018 Jun 26;23(13):3946-3959.e6. doi: 10.1016/j.celrep.2018.05.082. Cell Rep. 2018. PMID: 29949776 Free article.
42 results