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FGF19 action in the brain induces insulin-independent glucose lowering.
Morton GJ, Matsen ME, Bracy DP, Meek TH, Nguyen HT, Stefanovski D, Bergman RN, Wasserman DH, Schwartz MW. Morton GJ, et al. Among authors: matsen me. J Clin Invest. 2013 Nov;123(11):4799-808. doi: 10.1172/JCI70710. J Clin Invest. 2013. PMID: 24084738 Free PMC article.
Obesity is associated with hypothalamic injury in rodents and humans.
Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, Horvath TL, Baskin DG, Tschöp MH, Schwartz MW. Thaler JP, et al. Among authors: matsen me. J Clin Invest. 2012 Jan;122(1):153-62. doi: 10.1172/JCI59660. Epub 2011 Dec 27. J Clin Invest. 2012. PMID: 22201683 Free PMC article.
Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain.
Scarlett JM, Muta K, Brown JM, Rojas JM, Matsen ME, Acharya NK, Secher A, Ingvorsen C, Jorgensen R, Høeg-Jensen T, Stefanovski D, Bergman RN, Piccinini F, Kaiyala KJ, Shiota M, Morton GJ, Schwartz MW. Scarlett JM, et al. Among authors: matsen me. Diabetes. 2019 Mar;68(3):654-664. doi: 10.2337/db18-0498. Epub 2018 Dec 6. Diabetes. 2019. PMID: 30523024 Free PMC article.
In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue.
Matsen ME, Thaler JP, Wisse BE, Guyenet SJ, Meek TH, Ogimoto K, Cubelo A, Fischer JD, Kaiyala KJ, Schwartz MW, Morton GJ. Matsen ME, et al. Am J Physiol Endocrinol Metab. 2013 Apr 1;304(7):E734-46. doi: 10.1152/ajpendo.00488.2012. Epub 2013 Feb 5. Am J Physiol Endocrinol Metab. 2013. PMID: 23384771 Free PMC article.
28 results