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In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras-effector interaction.
Shima F, Yoshikawa Y, Ye M, Araki M, Matsumoto S, Liao J, Hu L, Sugimoto T, Ijiri Y, Takeda A, Nishiyama Y, Sato C, Muraoka S, Tamura A, Osoda T, Tsuda K, Miyakawa T, Fukunishi H, Shimada J, Kumasaka T, Yamamoto M, Kataoka T. Shima F, et al. Among authors: matsumoto s. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8182-7. doi: 10.1073/pnas.1217730110. Epub 2013 Apr 29. Proc Natl Acad Sci U S A. 2013. PMID: 23630290 Free PMC article.
Current status of the development of Ras inhibitors.
Shima F, Matsumoto S, Yoshikawa Y, Kawamura T, Isa M, Kataoka T. Shima F, et al. Among authors: matsumoto s. J Biochem. 2015 Aug;158(2):91-9. doi: 10.1093/jb/mvv060. Epub 2015 Jun 22. J Biochem. 2015. PMID: 26100833 Review.
5,784 results