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Effect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults: The DO-HEALTH Randomized Clinical Trial.
Bischoff-Ferrari HA, Vellas B, Rizzoli R, Kressig RW, da Silva JAP, Blauth M, Felson DT, McCloskey EV, Watzl B, Hofbauer LC, Felsenberg D, Willett WC, Dawson-Hughes B, Manson JE, Siebert U, Theiler R, Staehelin HB, de Godoi Rezende Costa Molino C, Chocano-Bedoya PO, Abderhalden LA, Egli A, Kanis JA, Orav EJ; DO-HEALTH Research Group. Bischoff-Ferrari HA, et al. JAMA. 2020 Nov 10;324(18):1855-1868. doi: 10.1001/jama.2020.16909. JAMA. 2020. PMID: 33170239 Free PMC article. Clinical Trial.
The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole-rat biology.
Buffenstein R, Amoroso V, Andziak B, Avdieiev S, Azpurua J, Barker AJ, Bennett NC, Brieño-Enríquez MA, Bronner GN, Coen C, Delaney MA, Dengler-Crish CM, Edrey YH, Faulkes CG, Frankel D, Friedlander G, Gibney PA, Gorbunova V, Hine C, Holmes MM, Jarvis JUM, Kawamura Y, Kutsukake N, Kenyon C, Khaled WT, Kikusui T, Kissil J, Lagestee S, Larson J, Lauer A, Lavrenchenko LA, Lee A, Levitt JB, Lewin GR, Lewis Hardell KN, Lin TD, Mason MJ, McCloskey D, McMahon M, Miura K, Mogi K, Narayan V, O'Connor TP, Okanoya K, O'Riain MJ, Park TJ, Place NJ, Podshivalova K, Pamenter ME, Pyott SJ, Reznick J, Ruby JG, Salmon AB, Santos-Sacchi J, Sarko DK, Seluanov A, Shepard A, Smith M, Storey KB, Tian X, Vice EN, Viltard M, Watarai A, Wywial E, Yamakawa M, Zemlemerova ED, Zions M, Smith ESJ. Buffenstein R, et al. Biol Rev Camb Philos Soc. 2022 Feb;97(1):115-140. doi: 10.1111/brv.12791. Epub 2021 Sep 3. Biol Rev Camb Philos Soc. 2022. PMID: 34476892 Free PMC article. Review.
MID Max: LC-MS/MS Method for Measuring the Precursor and Product Mass Isotopomer Distributions of Metabolic Intermediates and Cofactors for Metabolic Flux Analysis Applications.
McCloskey D, Young JD, Xu S, Palsson BO, Feist AM. McCloskey D, et al. Anal Chem. 2016 Jan 19;88(2):1362-70. doi: 10.1021/acs.analchem.5b03887. Epub 2015 Dec 24. Anal Chem. 2016. PMID: 26666286
The analytical challenges to acquire accurate isotopic data of intracellular metabolic intermediates for stationary, nonstationary, and dynamic metabolic flux analysis (MFA) are numerous. This work presents MID Max, a novel LC-MS/MS workflow, acquisition, and isotopomer de …
The analytical challenges to acquire accurate isotopic data of intracellular metabolic intermediates for stationary, nonstationary, and dyna …
Electrodeposited Thin-Film Micro-Thermoelectric Coolers with Extreme Heat Flux Handling and Microsecond Time Response.
Corbett S, Gautam D, Lal S, Yu K, Balla N, Cunningham G, Razeeb KM, Enright R, McCloskey D. Corbett S, et al. ACS Appl Mater Interfaces. 2021 Jan 13;13(1):1773-1782. doi: 10.1021/acsami.0c16614. Epub 2021 Jan 4. ACS Appl Mater Interfaces. 2021. PMID: 33393783
These thermoelectric parameters lead to a material ZT = 0.26(0.04), which, for our device structure, allowed a net cooling of deltaT(max) = 4.4(0.12) K. A response time of tau = 20 mus was measured experimentally. ...
These thermoelectric parameters lead to a material ZT = 0.26(0.04), which, for our device structure, allowed a net cooling of deltaT(max …
Human total, basal and activity energy expenditures are independent of ambient environmental temperature.
Zhang X, Yamada Y, Sagayama H, Ainslie PN, Blaak EE, Buchowski MS, Close GL, Cooper JA, Das SK, Dugas LR, Gurven M, El Hamdouchi A, Hu S, Joonas N, Katzmarzyk P, Kraus WE, Kushner RF, Leonard WR, Martin CK, Meijer EP, Neuhouser ML, Ojiambo RM, Pitsiladis YP, Plasqui G, Prentice RL, Racette SB, Ravussin E, Redman LM, Reynolds RM, Roberts SB, Sardinha LB, Silva AM, Stice E, Urlacher SS, Van Mil EA, Wood BM, Murphy-Alford AJ, Loechl C, Luke AH, Rood J, Schoeller DA, Westerterp KR, Wong WW, Pontzer H, Speakman JR; IAEA DLW database consortium. Zhang X, et al. iScience. 2022 Jun 28;25(8):104682. doi: 10.1016/j.isci.2022.104682. eCollection 2022 Aug 19. iScience. 2022. PMID: 35865134 Free PMC article.
Physical activity and fat-free mass during growth and in later life.
Westerterp KR, Yamada Y, Sagayama H, Ainslie PN, Andersen LF, Anderson LJ, Arab L, Baddou I, Bedu-Addo K, Blaak EE, Blanc S, Bonomi AG, Bouten CVC, Bovet P, Buchowski MS, Butte NF, Camps SGJA, Close GL, Cooper JA, Das SK, Cooper R, Dugas LR, Ekelund U, Entringer S, Forrester T, Fudge BW, Goris AH, Gurven M, Hambly C, El Hamdouchi A, Hoos MB, Hu S, Joonas N, Joosen AM, Katzmarzyk P, Kempen KP, Kimura M, Kraus WE, Kushner RF, Lambert EV, Leonard WR, Lessan N, Martin CK, Medin AC, Meijer EP, Morehen JC, Morton JP, Neuhouser ML, Nicklas TA, Ojiambo RM, Pietiläinen KH, Pitsiladis YP, Plange-Rhule J, Plasqui G, Prentice RL, Rabinovich RA, Racette SB, Raichlen DA, Ravussin E, Reynolds RM, Roberts SB, Schuit AJ, Sjödin AM, Stice E, Urlacher SS, Valenti G, Van Etten LM, Van Mil EA, Wells JCK, Wilson G, Wood BM, Yanovski J, Yoshida T, Zhang X, Murphy-Alford AJ, Loechl CU, Luke AH, Pontzer H, Rood J, Schoeller DA, Wong WW, Speakman JR; International Atomic Energy Agency Doubly Labeled Water database group. Westerterp KR, et al. Am J Clin Nutr. 2021 Nov 8;114(5):1583-1589. doi: 10.1093/ajcn/nqab260. Am J Clin Nutr. 2021. PMID: 34477824 Free PMC article.
Atp8a1 deficiency is associated with phosphatidylserine externalization in hippocampus and delayed hippocampus-dependent learning.
Levano K, Punia V, Raghunath M, Debata PR, Curcio GM, Mogha A, Purkayastha S, McCloskey D, Fata J, Banerjee P. Levano K, et al. J Neurochem. 2012 Jan;120(2):302-13. doi: 10.1111/j.1471-4159.2011.07543.x. Epub 2011 Dec 2. J Neurochem. 2012. PMID: 22007859 Free PMC article.
In corroboration, ectopic expression of Atp8a1 but not its close homolog, Atp8a2, caused an increase in the population (V(max) ) of PM-APLT without any change in its signature parameter K(m) in the neuronal N18 cells. Conversely, expression of a P-type phosphorylation-site …
In corroboration, ectopic expression of Atp8a1 but not its close homolog, Atp8a2, caused an increase in the population (V(max) ) of P …
The distribution, determinants, and clinical correlates of vertebral osteophytosis: a population based survey.
O'Neill TW, McCloskey EV, Kanis JA, Bhalla AK, Reeve J, Reid DM, Todd C, Woolf AD, Silman AJ. O'Neill TW, et al. J Rheumatol. 1999 Apr;26(4):842-8. J Rheumatol. 1999. PMID: 10229405
Based on these data 2 summary statistics were derived: the maximum osteophyte grade at any vertebral level (MAX), and the sum of the osteophyte grades at the individual vertebral levels (TOT). ...Both the sum of the individual grades (TOT) and the proportion of subjects wi …
Based on these data 2 summary statistics were derived: the maximum osteophyte grade at any vertebral level (MAX), and the sum of the …
Photoinduced C-N bond cleavage in 2-azido-1,3-diphenyl-propan-1-one derivatives: photorelease of hydrazoic acid.
Klima RF, Jadhav AV, Singh PN, Chang M, Vanos C, Sankaranarayanan J, Vu M, Ibrahim N, Ross E, McCloskey S, Murthy RS, Krause JA, Ault BS, Gudmundsdóttir AD. Klima RF, et al. J Org Chem. 2007 Aug 17;72(17):6372-81. doi: 10.1021/jo070558q. Epub 2007 Jul 27. J Org Chem. 2007. PMID: 17655357
Laser flash photolysis (308 nm) of 1a,b in acetonitrile reveals a transient absorption (lambda max = approximately 310 nm) due to the formation of radicals 4a and 4b, respectively, which have lifetimes of approximately 14 micros at ambient temperature. ...
Laser flash photolysis (308 nm) of 1a,b in acetonitrile reveals a transient absorption (lambda max = approximately 310 nm) due to the …
11 results