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A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
Mahoney M, Damalanka VC, Tartell MA, Chung DH, Lourenço AL, Pwee D, Mayer Bridwell AE, Hoffmann M, Voss J, Karmakar P, Azouz NP, Klingler AM, Rothlauf PW, Thompson CE, Lee M, Klampfer L, Stallings CL, Rothenberg ME, Pöhlmann S, Whelan SPJ, O'Donoghue AJ, Craik CS, Janetka JW. Mahoney M, et al. Among authors: mayer bridwell ae. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2108728118. doi: 10.1073/pnas.2108728118. Proc Natl Acad Sci U S A. 2021. PMID: 34635581 Free PMC article.
A promising bioconjugate vaccine against hypervirulent Klebsiella pneumoniae.
Feldman MF, Mayer Bridwell AE, Scott NE, Vinogradov E, McKee SR, Chavez SM, Twentyman J, Stallings CL, Rosen DA, Harding CM. Feldman MF, et al. Among authors: mayer bridwell ae. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18655-18663. doi: 10.1073/pnas.1907833116. Epub 2019 Aug 27. Proc Natl Acad Sci U S A. 2019. PMID: 31455739 Free PMC article.
Perspectives and Advances in the Understanding of Tuberculosis.
Kinsella RL, Zhu DX, Harrison GA, Mayer Bridwell AE, Prusa J, Chavez SM, Stallings CL. Kinsella RL, et al. Among authors: mayer bridwell ae. Annu Rev Pathol. 2021 Jan 24;16:377-408. doi: 10.1146/annurev-pathol-042120-032916. Annu Rev Pathol. 2021. PMID: 33497258 Review.
Design, Synthesis, and Evaluation of Novel Δ2-Thiazolino 2-Pyridone Derivatives That Potentiate Isoniazid Activity in an Isoniazid-Resistant Mycobacterium tuberculosis Mutant.
Sarkar S, Mayer Bridwell AE, Good JAD, Wang ER, McKee SR, Valenta J, Harrison GA, Flentie KN, Henry FL, Wixe T, Demirel P, Vagolu SK, Chatagnon J, Machelart A, Brodin P, Tønjum T, Stallings CL, Almqvist F. Sarkar S, et al. Among authors: mayer bridwell ae. J Med Chem. 2023 Aug 24;66(16):11056-11077. doi: 10.1021/acs.jmedchem.3c00358. Epub 2023 Jul 24. J Med Chem. 2023. PMID: 37485869 Free PMC article.
A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
Mahoney M, Damalanka VC, Tartell MA, Chung DH, Lourenco AL, Pwee D, Mayer Bridwell AE, Hoffmann M, Voss J, Karmakar P, Azouz N, Klingler AM, Rothlauf PW, Thompson CE, Lee M, Klampfer L, Stallings C, Rothenberg ME, Pöhlmann S, Whelan SP, O'Donoghue AJ, Craik CS, Janetka JW. Mahoney M, et al. Among authors: mayer bridwell ae. bioRxiv [Preprint]. 2021 May 6:2021.05.06.442935. doi: 10.1101/2021.05.06.442935. bioRxiv. 2021. PMID: 34131661 Free PMC article. Updated. Preprint.