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A phase 1 study in healthy participants to characterize the safety and pharmacology of inclacumab, a fully human anti-P-selectin antibody, in development for treatment of sickle cell disease.
Mayer CL, Koeck K, Hottmann M, Redfern A, Davis M, Barth A, Geng X, Hoppe C, Yue P. Mayer CL, et al. Eur J Clin Pharmacol. 2023 Sep;79(9):1219-1228. doi: 10.1007/s00228-023-03514-3. Epub 2023 Jul 12. Eur J Clin Pharmacol. 2023. PMID: 37436495 Free PMC article. Clinical Trial.
Blast exposure causes dynamic microglial/macrophage responses and microdomains of brain microvessel dysfunction.
Huber BR, Meabon JS, Hoffer ZS, Zhang J, Hoekstra JG, Pagulayan KF, McMillan PJ, Mayer CL, Banks WA, Kraemer BC, Raskind MA, McGavern DB, Peskind ER, Cook DG. Huber BR, et al. Among authors: mayer cl. Neuroscience. 2016 Apr 5;319:206-20. doi: 10.1016/j.neuroscience.2016.01.022. Epub 2016 Jan 14. Neuroscience. 2016. PMID: 26777891 Free PMC article.
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