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Discovery and optimization of 2-pyridinone aminal integrase strand transfer inhibitors for the treatment of HIV.
Bioorg Med Chem Lett. 2017 May 1;27(9):2038-2046. doi: 10.1016/j.bmcl.2017.02.039. Epub 2017 Feb 20.
Bioorg Med Chem Lett. 2017.
PMID: 28285916
Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors.
Raheem IT, Walji AM, Klein D, Sanders JM, Powell DA, Abeywickrema P, Barbe G, Bennet A, Childers K, Christensen M, Clas SD, Dubost D, Embrey M, Grobler J, Hafey MJ, Hartingh TJ, Hazuda DJ, Kuethe JT, McCabe Dunn J, Miller MD, Moore KP, Nolting A, Pajkovic N, Patel S, Peng Z, Rada V, Rearden P, Schreier JD, Sisko J, Steele TG, Truchon JF, Wai J, Xu M, Coleman PJ.
Raheem IT, et al. Among authors: mccabe dunn j.
J Med Chem. 2015 Oct 22;58(20):8154-65. doi: 10.1021/acs.jmedchem.5b01037. Epub 2015 Oct 8.
J Med Chem. 2015.
PMID: 26397965
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Correction to Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors.
Raheem IT, Walji AM, Klein D, Sanders JM, Powell DA, Abeywickrema P, Barbe G, Bennet A, Childers K, Christensen M, Clas SD, Dubost D, Embrey M, Grobler J, Hafey MJ, Hartingh TJ, Hazuda DJ, Kuethe JT, McCabe Dunn J, Miller MD, Moore KP, Nolting A, Pajkovic N, Patel S, Peng Z, Rada V, Rearden P, Schreier JD, Sisko J, Steele TG, Truchon JF, Wai J, Xu M, Coleman PJ.
Raheem IT, et al. Among authors: mccabe dunn j.
J Med Chem. 2016 Jan 14;59(1):486. doi: 10.1021/acs.jmedchem.5b01957. Epub 2015 Dec 28.
J Med Chem. 2016.
PMID: 26709958
No abstract available.
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Development of a novel tricyclic class of potent and selective FIXa inhibitors.
Meng D, Andre P, Bateman TJ, Berger R, Chen YH, Desai K, Dewnani S, Ellsworth K, Feng D, Geissler WM, Guo L, Hruza A, Jian T, Li H, Metzger J, Parker DL, Reichert P, Sherer EC, Smith CJ, Sonatore LM, Tschirret-Guth R, Wu J, Xu J, Zhang T, Campeau LC, Orr R, Poirier M, McCabe-Dunn J, Araki K, Nishimura T, Sakurada I, Hirabayashi T, Wood HB.
Meng D, et al. Among authors: mccabe dunn j.
Bioorg Med Chem Lett. 2015 Nov 15;25(22):5437-43. doi: 10.1016/j.bmcl.2015.07.078. Epub 2015 Jul 31.
Bioorg Med Chem Lett. 2015.
PMID: 26318999
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Development of a palladium-catalyzed α-arylation of cyclopropyl nitriles.
McCabe Dunn JM, Kuethe JT, Orr RK, Tudge M, Campeau LC.
McCabe Dunn JM, et al.
Org Lett. 2014 Dec 19;16(24):6314-7. doi: 10.1021/ol5030426. Epub 2014 Dec 4.
Org Lett. 2014.
PMID: 25474721
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Total Synthesis of Darobactin A.
Nesic M, Ryffel DB, Maturano J, Shevlin M, Pollack SR, Gauthier DR Jr, Trigo-Mouriño P, Zhang LK, Schultz DM, McCabe Dunn JM, Campeau LC, Patel NR, Petrone DA, Sarlah D.
Nesic M, et al. Among authors: mccabe dunn jm.
J Am Chem Soc. 2022 Aug 10;144(31):14026-14030. doi: 10.1021/jacs.2c05891. Epub 2022 Jul 28.
J Am Chem Soc. 2022.
PMID: 35900216
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Selective Formation of Functionalized α-Quaternary Malononitriles toward 5,5-Disubstituted Pyrrolopyrimidinones.
Whitehead A, Zhang Y, McCabe Dunn J, Sherer EC, Lam YH, Stelmach J, Sun A, Shiroda M, Orr RK, Waddell ST, Raghavan S.
Whitehead A, et al. Among authors: mccabe dunn j.
Org Lett. 2017 Sep 1;19(17):4448-4451. doi: 10.1021/acs.orglett.7b01930. Epub 2017 Aug 16.
Org Lett. 2017.
PMID: 28812897
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The protecting-group free selective 3'-functionalization of nucleosides.
McCabe Dunn JM, Reibarkh M, Sherer EC, Orr RK, Ruck RT, Simmons B, Bellomo A.
McCabe Dunn JM, et al.
Chem Sci. 2017 Apr 1;8(4):2804-2810. doi: 10.1039/c6sc05081f. Epub 2017 Jan 18.
Chem Sci. 2017.
PMID: 28553517
Free PMC article.
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