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Defining the early stages of intestinal colonisation by whipworms.
Duque-Correa MA, Goulding D, Rodgers FH, Gillis JA, Cormie C, Rawlinson KA, Bancroft AJ, Bennett HM, Lotkowska ME, Reid AJ, Speak AO, Scott P, Redshaw N, Tolley C, McCarthy C, Brandt C, Sharpe C, Ridley C, Moya JG, Carneiro CM, Starborg T, Hayes KS, Holroyd N, Sanders M, Thornton DJ, Grencis RK, Berriman M. Duque-Correa MA, et al. Among authors: mccarthy c. Nat Commun. 2022 Apr 1;13(1):1725. doi: 10.1038/s41467-022-29334-0. Nat Commun. 2022. PMID: 35365634 Free PMC article.
Exclusive dependence of IL-10Rα signalling on intestinal microbiota homeostasis and control of whipworm infection.
Duque-Correa MA, Karp NA, McCarthy C, Forman S, Goulding D, Sankaranarayanan G, Jenkins TP, Reid AJ, Cambridge EL, Ballesteros Reviriego C; Sanger Mouse Genetics Project; 3i consortium; Müller W, Cantacessi C, Dougan G, Grencis RK, Berriman M. Duque-Correa MA, et al. Among authors: mccarthy c. PLoS Pathog. 2019 Jan 14;15(1):e1007265. doi: 10.1371/journal.ppat.1007265. eCollection 2019 Jan. PLoS Pathog. 2019. PMID: 30640950 Free PMC article.
Evaluation of DNA Extraction Methods on Individual Helminth Egg and Larval Stages for Whole-Genome Sequencing.
Doyle SR, Sankaranarayanan G, Allan F, Berger D, Jimenez Castro PD, Collins JB, Crellen T, Duque-Correa MA, Ellis P, Jaleta TG, Laing R, Maitland K, McCarthy C, Moundai T, Softley B, Thiele E, Ouakou PT, Tushabe JV, Webster JP, Weiss AJ, Lok J, Devaney E, Kaplan RM, Cotton JA, Berriman M, Holroyd N. Doyle SR, et al. Among authors: mccarthy c. Front Genet. 2019 Sep 20;10:826. doi: 10.3389/fgene.2019.00826. eCollection 2019. Front Genet. 2019. PMID: 31616465 Free PMC article.
Systematic screening of 96 Schistosoma mansoni cell-surface and secreted antigens does not identify any strongly protective vaccine candidates in a mouse model of infection.
Crosnier C, Brandt C, Rinaldi G, McCarthy C, Barker C, Clare S, Berriman M, Wright GJ. Crosnier C, et al. Among authors: mccarthy c. Wellcome Open Res. 2019 Oct 16;4:159. doi: 10.12688/wellcomeopenres.15487.1. eCollection 2019. Wellcome Open Res. 2019. PMID: 31728414 Free PMC article.
Daily rhythms in gene expression of the human parasite Schistosoma mansoni.
Rawlinson KA, Reid AJ, Lu Z, Driguez P, Wawer A, Coghlan A, Sankaranarayanan G, Buddenborg SK, Soria CD, McCarthy C, Holroyd N, Sanders M, Hoffmann KF, Wilcockson D, Rinaldi G, Berriman M. Rawlinson KA, et al. Among authors: mccarthy c. BMC Biol. 2021 Dec 2;19(1):255. doi: 10.1186/s12915-021-01189-9. BMC Biol. 2021. PMID: 34852797 Free PMC article.
The gut microbial metabolic capacity of microbiome-humanized vs. wild type rodents reveals a likely dual role of intestinal bacteria in hepato-intestinal schistosomiasis.
Cortés A, Martin J, Rosa BA, Stark KA, Clare S, McCarthy C, Harcourt K, Brandt C, Tolley C, Lawley TD, Mitreva M, Berriman M, Rinaldi G, Cantacessi C. Cortés A, et al. Among authors: mccarthy c. PLoS Negl Trop Dis. 2022 Oct 24;16(10):e0010878. doi: 10.1371/journal.pntd.0010878. eCollection 2022 Oct. PLoS Negl Trop Dis. 2022. PMID: 36279280 Free PMC article.
A drug repurposing screen for whipworms informed by comparative genomics.
Coghlan A, Partridge FA, Duque-Correa MA, Rinaldi G, Clare S, Seymour L, Brandt C, Mkandawire TT, McCarthy C, Holroyd N, Nick M, Brown AE, Tonitiwong S, Sattelle DB, Berriman M. Coghlan A, et al. Among authors: mccarthy c. PLoS Negl Trop Dis. 2023 Sep 5;17(9):e0011205. doi: 10.1371/journal.pntd.0011205. eCollection 2023 Sep. PLoS Negl Trop Dis. 2023. PMID: 37669291 Free PMC article.
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.
Balmus G, Larrieu D, Barros AC, Collins C, Abrudan M, Demir M, Geisler NJ, Lelliott CJ, White JK, Karp NA, Atkinson J, Kirton A, Jacobsen M, Clift D, Rodriguez R; Sanger Mouse Genetics Project; Adams DJ, Jackson SP. Balmus G, et al. Nat Commun. 2018 Apr 27;9(1):1700. doi: 10.1038/s41467-018-03770-3. Nat Commun. 2018. PMID: 29703891 Free PMC article.
Ethical, legal, and social issues in the Earth BioGenome Project.
Sherkow JS, Barker KB, Braverman I, Cook-Deegan R, Durbin R, Easter CL, Goldstein MM, Hudson M, Kress WJ, Lewin HA, Mathews DJH, McCarthy C, McCartney AM, da Silva M, Torrance AW, Greely HT. Sherkow JS, et al. Among authors: mccarthy c. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2115859119. doi: 10.1073/pnas.2115859119. Proc Natl Acad Sci U S A. 2022. PMID: 35042809 Free PMC article.
1,780 results