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Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial.
Lancet. 2009 Nov 7;374(9701):1597-605. doi: 10.1016/S0140-6736(09)61836-5. Epub 2009 Oct 23.
Lancet. 2009.
PMID: 19854499
Free PMC article.
Clinical Trial.
Safety and efficacy of gene transfer for Leber's congenital amaurosis.
Maguire AM, Simonelli F, Pierce EA, Pugh EN Jr, Mingozzi F, Bennicelli J, Banfi S, Marshall KA, Testa F, Surace EM, Rossi S, Lyubarsky A, Arruda VR, Konkle B, Stone E, Sun J, Jacobs J, Dell'Osso L, Hertle R, Ma JX, Redmond TM, Zhu X, Hauck B, Zelenaia O, Shindler KS, Maguire MG, Wright JF, Volpe NJ, McDonnell JW, Auricchio A, High KA, Bennett J.
Maguire AM, et al. Among authors: mcdonnell jw.
N Engl J Med. 2008 May 22;358(21):2240-8. doi: 10.1056/NEJMoa0802315. Epub 2008 Apr 27.
N Engl J Med. 2008.
PMID: 18441370
Free PMC article.
Clinical Trial.
Item in Clipboard
Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration.
Simonelli F, Maguire AM, Testa F, Pierce EA, Mingozzi F, Bennicelli JL, Rossi S, Marshall K, Banfi S, Surace EM, Sun J, Redmond TM, Zhu X, Shindler KS, Ying GS, Ziviello C, Acerra C, Wright JF, McDonnell JW, High KA, Bennett J, Auricchio A.
Simonelli F, et al. Among authors: mcdonnell jw.
Mol Ther. 2010 Mar;18(3):643-50. doi: 10.1038/mt.2009.277. Epub 2009 Dec 1.
Mol Ther. 2010.
PMID: 19953081
Free PMC article.
Clinical Trial.
Item in Clipboard
Separation of adeno-associated virus type 2 empty particles from genome containing vectors by anion-exchange column chromatography.
Qu G, Bahr-Davidson J, Prado J, Tai A, Cataniag F, McDonnell J, Zhou J, Hauck B, Luna J, Sommer JM, Smith P, Zhou S, Colosi P, High KA, Pierce GF, Wright JF.
Qu G, et al.
J Virol Methods. 2007 Mar;140(1-2):183-92. doi: 10.1016/j.jviromet.2006.11.019. Epub 2006 Dec 28.
J Virol Methods. 2007.
PMID: 17196264
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Adeno-associated virus (AAV) capsid genes isolated from rat and mouse liver genomic DNA define two new AAV species distantly related to AAV-5.
Lochrie MA, Tatsuno GP, Arbetman AE, Jones K, Pater C, Smith PH, McDonnell JW, Zhou SZ, Kachi S, Kachi M, Campochiaro PA, Pierce GF, Colosi P.
Lochrie MA, et al. Among authors: mcdonnell jw.
Virology. 2006 Sep 15;353(1):68-82. doi: 10.1016/j.virol.2006.05.023. Epub 2006 Jun 30.
Virology. 2006.
PMID: 16806384
Free article.
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Mutations on the external surfaces of adeno-associated virus type 2 capsids that affect transduction and neutralization.
Lochrie MA, Tatsuno GP, Christie B, McDonnell JW, Zhou S, Surosky R, Pierce GF, Colosi P.
Lochrie MA, et al. Among authors: mcdonnell jw.
J Virol. 2006 Jan;80(2):821-34. doi: 10.1128/JVI.80.2.821-834.2006.
J Virol. 2006.
PMID: 16378984
Free PMC article.
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Determining nursing costs: a strategy for professional survival.
Stanfill PH, McDonnell JW.
Stanfill PH, et al. Among authors: mcdonnell jw.
Oncol Nurs Forum. 1985 Sep-Oct;12(5):79-82.
Oncol Nurs Forum. 1985.
PMID: 3929233
No abstract available.
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