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Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging.
Hickey JW, Neumann EK, Radtke AJ, Camarillo JM, Beuschel RT, Albanese A, McDonough E, Hatler J, Wiblin AE, Fisher J, Croteau J, Small EC, Sood A, Caprioli RM, Angelo RM, Nolan GP, Chung K, Hewitt SM, Germain RN, Spraggins JM, Lundberg E, Snyder MP, Kelleher NL, Saka SK. Hickey JW, et al. Among authors: mcdonough e. Nat Methods. 2022 Mar;19(3):284-295. doi: 10.1038/s41592-021-01316-y. Epub 2021 Nov 22. Nat Methods. 2022. PMID: 34811556 Free PMC article. Review.
Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue.
Gerdes MJ, Sevinsky CJ, Sood A, Adak S, Bello MO, Bordwell A, Can A, Corwin A, Dinn S, Filkins RJ, Hollman D, Kamath V, Kaanumalle S, Kenny K, Larsen M, Lazare M, Li Q, Lowes C, McCulloch CC, McDonough E, Montalto MC, Pang Z, Rittscher J, Santamaria-Pang A, Sarachan BD, Seel ML, Seppo A, Shaikh K, Sui Y, Zhang J, Ginty F. Gerdes MJ, et al. Among authors: mcdonough e. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11982-7. doi: 10.1073/pnas.1300136110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818604 Free PMC article.
Multi-protein spatial signatures in ductal carcinoma in situ (DCIS) of breast.
Badve SS, Cho S, Gökmen-Polar Y, Sui Y, Chadwick C, McDonough E, Sood A, Taylor M, Zavodszky M, Tan PH, Gerdes M, Harris AL, Ginty F. Badve SS, et al. Among authors: mcdonough e. Br J Cancer. 2021 Mar;124(6):1150-1159. doi: 10.1038/s41416-020-01216-6. Epub 2021 Jan 7. Br J Cancer. 2021. PMID: 33414541 Free PMC article.
Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging.
Quardokus EM, Saunders DC, McDonough E, Hickey JW, Werlein C, Surrette C, Rajbhandari P, Casals AM, Tian H, Lowery L, Neumann EK, Björklund F, Neelakantan TV, Croteau J, Wiblin AE, Fisher J, Livengood AJ, Dowell KG, Silverstein JC, Spraggins JM, Pryhuber GS, Deutsch G, Ginty F, Nolan GP, Melov S, Jonigk D, Caldwell MA, Vlachos IS, Muller W, Gehlenborg N, Stockwell BR, Lundberg E, Snyder MP, Germain RN, Camarillo JM, Kelleher NL, Börner K, Radtke AJ. Quardokus EM, et al. Among authors: mcdonough e. Nat Methods. 2023 Aug;20(8):1174-1178. doi: 10.1038/s41592-023-01846-7. Epub 2023 Jul 19. Nat Methods. 2023. PMID: 37468619 Free PMC article.
3D reconstruction of skin and spatial mapping of immune cell density, vascular distance and effects of sun exposure and aging.
Ghose S, Ju Y, McDonough E, Ho J, Karunamurthy A, Chadwick C, Cho S, Rose R, Corwin A, Surrette C, Martinez J, Williams E, Sood A, Al-Kofahi Y, Falo LD Jr, Börner K, Ginty F. Ghose S, et al. Among authors: mcdonough e. Commun Biol. 2023 Jul 19;6(1):718. doi: 10.1038/s42003-023-04991-z. Commun Biol. 2023. PMID: 37468758 Free PMC article.
Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas.
Berens ME, Sood A, Barnholtz-Sloan JS, Graf JF, Cho S, Kim S, Kiefer J, Byron SA, Halperin RF, Nasser S, Adkins J, Cuyugan L, Devine K, Ostrom Q, Couce M, Wolansky L, McDonough E, Schyberg S, Dinn S, Sloan AE, Prados M, Phillips JJ, Nelson SJ, Liang WS, Al-Kofahi Y, Rusu M, Zavodszky MI, Ginty F. Berens ME, et al. Among authors: mcdonough e. PLoS One. 2019 Dec 27;14(12):e0219724. doi: 10.1371/journal.pone.0219724. eCollection 2019. PLoS One. 2019. PMID: 31881020 Free PMC article.
FLINO: a new method for immunofluorescence bioimage normalization.
Graf J, Cho S, McDonough E, Corwin A, Sood A, Lindner A, Salvucci M, Stachtea X, Van Schaeybroeck S, Dunne PD, Laurent-Puig P, Longley D, Prehn JHM, Ginty F. Graf J, et al. Among authors: mcdonough e. Bioinformatics. 2022 Jan 3;38(2):520-526. doi: 10.1093/bioinformatics/btab686. Bioinformatics. 2022. PMID: 34601553 Free PMC article.
Stratification of chemotherapy-treated stage III colorectal cancer patients using multiplexed imaging and single-cell analysis of T-cell populations.
Stachtea X, Loughrey MB, Salvucci M, Lindner AU, Cho S, McDonough E, Sood A, Graf J, Santamaria-Pang A, Corwin A, Laurent-Puig P, Dasgupta S, Shia J, Owens JR, Abate S, Van Schaeybroeck S, Lawler M, Prehn JHM, Ginty F, Longley DB. Stachtea X, et al. Among authors: mcdonough e. Mod Pathol. 2022 Apr;35(4):564-576. doi: 10.1038/s41379-021-00953-0. Epub 2021 Nov 3. Mod Pathol. 2022. PMID: 34732839 Free PMC article.
138 results