McDonough MA - Search Results

1

Structure-Activity Relationship and Crystallographic Studies on 4-Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors.

Holt-Martyn JP, Chowdhury R, Tumber A, Yeh TL, Abboud MI, Lippl K, Lohans CT, Langley GW, Figg W Jr, McDonough MA, Pugh CW, Ratcliffe PJ, Schofield CJ. Holt-Martyn JP, et al. Among authors: mcdonough ma. ChemMedChem. 2020 Feb 5;15(3):270-273. doi: 10.1002/cmdc.201900557. Epub 2019 Dec 3. ChemMedChem. 2020. PMID: 31751494 Free PMC article.

2

New structural insights into the inhibition of serine proteases by cyclic peptides from bacteria.

McDonough MA, Schofield CJ. McDonough MA, et al. Chem Biol. 2003 Oct;10(10):898-900. doi: 10.1016/j.chembiol.2003.10.002. Chem Biol. 2003. PMID: 14583255 No abstract available.

3

Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity.

Lancaster DE, McNeill LA, McDonough MA, Aplin RT, Hewitson KS, Pugh CW, Ratcliffe PJ, Schofield CJ. Lancaster DE, et al. Among authors: mcdonough ma. Biochem J. 2004 Nov 1;383(Pt. 3):429-37. doi: 10.1042/BJ20040735. Biochem J. 2004. PMID: 15239670 Free PMC article.

4

Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases.

Lancaster DE, McDonough MA, Schofield CJ. Lancaster DE, et al. Among authors: mcdonough ma. Biochem Soc Trans. 2004 Dec;32(Pt 6):943-5. doi: 10.1042/BST0320943. Biochem Soc Trans. 2004. PMID: 15506931 Review.

5

OS-9: another piece in the HIF complex story.

Flashman E, McDonough MA, Schofield CJ. Flashman E, et al. Among authors: mcdonough ma. Mol Cell. 2005 Feb 18;17(4):472-3. doi: 10.1016/j.molcel.2005.02.001. Mol Cell. 2005. PMID: 15721249 Free article. Review.

6

Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling.

Hewitson KS, Granatino N, Welford RW, McDonough MA, Schofield CJ. Hewitson KS, et al. Among authors: mcdonough ma. Philos Trans A Math Phys Eng Sci. 2005 Apr 15;363(1829):807-28; discussion 1035-40. doi: 10.1098/rsta.2004.1540. Philos Trans A Math Phys Eng Sci. 2005. PMID: 15901537 Review.

7

Selective inhibition of factor inhibiting hypoxia-inducible factor.

McDonough MA, McNeill LA, Tilliet M, Papamicaël CA, Chen QY, Banerji B, Hewitson KS, Schofield CJ. McDonough MA, et al. J Am Chem Soc. 2005 Jun 1;127(21):7680-1. doi: 10.1021/ja050841b. J Am Chem Soc. 2005. PMID: 15913349

8

Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.

Sleeman MC, Sorensen JL, Batchelar ET, McDonough MA, Schofield CJ. Sleeman MC, et al. Among authors: mcdonough ma. J Biol Chem. 2005 Oct 14;280(41):34956-65. doi: 10.1074/jbc.M507196200. Epub 2005 Aug 11. J Biol Chem. 2005. PMID: 16096274 Free article.

9

Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.

McDonough MA, Kavanagh KL, Butler D, Searls T, Oppermann U, Schofield CJ. McDonough MA, et al. J Biol Chem. 2005 Dec 9;280(49):41101-10. doi: 10.1074/jbc.M507528200. Epub 2005 Sep 25. J Biol Chem. 2005. PMID: 16186124 Free article.

10

The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by beta-oxocarboxylic acids.

Banerji B, Conejo-Garcia A, McNeill LA, McDonough MA, Buck MR, Hewitson KS, Oldham NJ, Schofield CJ. Banerji B, et al. Among authors: mcdonough ma. Chem Commun (Camb). 2005 Nov 21;(43):5438-40. doi: 10.1039/b510707e. Epub 2005 Oct 4. Chem Commun (Camb). 2005. PMID: 16261239

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