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Predictive liver lipid biomarker signature of Acetyl-coenzyme A carboxylase inhibitor related developmental toxicity in non-pregnant female Han Wistar rats - Lipidomics biomarker discovery and validation.
Swindale LY, Stevens AJ, Whalley SJ, Currie RA, Jessop KM, Lai F, Lim PP, McInnes EF, Cowie D, Kende A. Swindale LY, et al. Among authors: mcinnes ef. Toxicol Lett. 2023 May 1;380:62-68. doi: 10.1016/j.toxlet.2023.03.009. Epub 2023 Mar 29. Toxicol Lett. 2023. PMID: 36996930
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Related Neurodevelopmental Toxicity Testing and Assessment Scheme (Thyroid-NDT-TAS).
Melching-Kollmuss S, Bothe K, Charlton A, Gangadharan B, Ghaffari R, Jacobi S, Marty S, Marxfeld HA, McInnes EF, Sauer UG, Sheets LP, Strupp C, Tinwell H, Wiemann C, Botham PA, van Ravenzwaay B. Melching-Kollmuss S, et al. Among authors: mcinnes ef. Crit Rev Toxicol. 2023 Jul;53(6):339-371. doi: 10.1080/10408444.2023.2231033. Epub 2023 Aug 9. Crit Rev Toxicol. 2023. PMID: 37554099 Review.
Concerns about pathology expertise and data quality.
McInnes EF, Meyerholz DK, Arends MJ. McInnes EF, et al. J Pathol. 2023 Apr;259(4):468. doi: 10.1002/path.6058. Epub 2023 Feb 24. J Pathol. 2023. PMID: 36715663 No abstract available.
Scientific and Regulatory Policy Committee Best Practices: Recommended ("Best") Practices for Informed (Non-blinded) Versus Masked (Blinded) Microscopic Evaluation in Animal Toxicity Studies.
Bolon B, Francke S, Caverly Rae JM, Polack E, Regan KS, McInnes EF, Young JK, Keane K, Perry R, Romeike A, Colman K, Jensen K, Nakano-Ito K, Galbreath EJ. Bolon B, et al. Among authors: mcinnes ef. Toxicol Pathol. 2022 Dec;50(8):930-941. doi: 10.1177/01926233221135563. Epub 2022 Nov 14. Toxicol Pathol. 2022. PMID: 36377245
32 results