McPhie D - Search Results

1

Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder.

Kathuria A, Lopez-Lengowski K, Vater M, McPhie D, Cohen BM, Karmacharya R. Kathuria A, et al. Among authors: mcphie d. Genome Med. 2020 Apr 19;12(1):34. doi: 10.1186/s13073-020-00733-6. Genome Med. 2020. PMID: 32306996 Free PMC article.

2

Synaptic deficits in iPSC-derived cortical interneurons in schizophrenia are mediated by NLGN2 and rescued by N-acetylcysteine.

Kathuria A, Lopez-Lengowski K, Watmuff B, McPhie D, Cohen BM, Karmacharya R. Kathuria A, et al. Among authors: mcphie d. Transl Psychiatry. 2019 Nov 28;9(1):321. doi: 10.1038/s41398-019-0660-x. Transl Psychiatry. 2019. PMID: 31780643 Free PMC article.

3

Transcriptomic Landscape and Functional Characterization of Induced Pluripotent Stem Cell-Derived Cerebral Organoids in Schizophrenia.

Kathuria A, Lopez-Lengowski K, Jagtap SS, McPhie D, Perlis RH, Cohen BM, Karmacharya R. Kathuria A, et al. Among authors: mcphie d. JAMA Psychiatry. 2020 Jul 1;77(7):745-754. doi: 10.1001/jamapsychiatry.2020.0196. JAMA Psychiatry. 2020. PMID: 32186681 Free PMC article.

4

Perturbational Profiling of Metabolites in Patient Fibroblasts Implicates α-Aminoadipate as a Potential Biomarker for Bipolar Disorder.

Huang JH, Berkovitch SS, Iaconelli J, Watmuff B, Park H, Chattopadhyay S, McPhie D, Öngür D, Cohen BM, Clish CB, Karmacharya R. Huang JH, et al. Among authors: mcphie d. Mol Neuropsychiatry. 2016 Jul;2(2):97-106. doi: 10.1159/000446654. Epub 2016 Jun 24. Mol Neuropsychiatry. 2016. PMID: 27606323 Free PMC article.

5

Abnormalities in mitochondrial structure in cells from patients with bipolar disorder.

Cataldo AM, McPhie DL, Lange NT, Punzell S, Elmiligy S, Ye NZ, Froimowitz MP, Hassinger LC, Menesale EB, Sargent LW, Logan DJ, Carpenter AE, Cohen BM. Cataldo AM, et al. Am J Pathol. 2010 Aug;177(2):575-85. doi: 10.2353/ajpath.2010.081068. Epub 2010 Jun 21. Am J Pathol. 2010. PMID: 20566748 Free PMC article.

6

Unbiased Metabolite Profiling of Schizophrenia Fibroblasts under Stressful Perturbations Reveals Dysregulation of Plasmalogens and Phosphatidylcholines.

Huang JH, Park H, Iaconelli J, Berkovitch SS, Watmuff B, McPhie D, Öngür D, Cohen BM, Clish CB, Karmacharya R. Huang JH, et al. Among authors: mcphie d. J Proteome Res. 2017 Feb 3;16(2):481-493. doi: 10.1021/acs.jproteome.6b00628. Epub 2016 Nov 28. J Proteome Res. 2017. PMID: 28152600

7

Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder.

Robicsek O, Ene HM, Karry R, Ytzhaki O, Asor E, McPhie D, Cohen BM, Ben-Yehuda R, Weiner I, Ben-Shachar D. Robicsek O, et al. Among authors: mcphie d. Schizophr Bull. 2018 Feb 15;44(2):432-442. doi: 10.1093/schbul/sbx077. Schizophr Bull. 2018. PMID: 28586483 Free PMC article.

8

Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia.

Park GH, Noh H, Shao Z, Ni P, Qin Y, Liu D, Beaudreault CP, Park JS, Abani CP, Park JM, Le DT, Gonzalez SZ, Guan Y, Cohen BM, McPhie DL, Coyle JT, Lanz TA, Xi HS, Yin C, Huang W, Kim HY, Chung S. Park GH, et al. Among authors: mcphie dl. Nat Neurosci. 2020 Nov;23(11):1352-1364. doi: 10.1038/s41593-020-00724-1. Epub 2020 Oct 23. Nat Neurosci. 2020. PMID: 33097921 Free PMC article.

9

The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia.

Nehme R, Pietiläinen O, Artomov M, Tegtmeyer M, Valakh V, Lehtonen L, Bell C, Singh T, Trehan A, Sherwood J, Manning D, Peirent E, Malik R, Guss EJ, Hawes D, Beccard A, Bara AM, Hazelbaker DZ, Zuccaro E, Genovese G, Loboda AA, Neumann A, Lilliehook C, Kuismin O, Hamalainen E, Kurki M, Hultman CM, Kähler AK, Paulo JA, Ganna A, Madison J, Cohen B, McPhie D, Adolfsson R, Perlis R, Dolmetsch R, Farhi S, McCarroll S, Hyman S, Neale B, Barrett LE, Harper W, Palotie A, Daly M, Eggan K. Nehme R, et al. Among authors: mcphie d. Nat Commun. 2022 Jun 27;13(1):3690. doi: 10.1038/s41467-022-31436-8. Nat Commun. 2022. PMID: 35760976 Free PMC article.

10

Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons.

Yoshimizu T, Pan JQ, Mungenast AE, Madison JM, Su S, Ketterman J, Ongur D, McPhie D, Cohen B, Perlis R, Tsai LH. Yoshimizu T, et al. Among authors: mcphie d. Mol Psychiatry. 2015 Feb;20(2):162-9. doi: 10.1038/mp.2014.143. Epub 2014 Nov 18. Mol Psychiatry. 2015. PMID: 25403839 Free PMC article.

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