Meek ME - Search Results

1

Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.

Thomas RS, Philbert MA, Auerbach SS, Wetmore BA, Devito MJ, Cote I, Rowlands JC, Whelan MP, Hays SM, Andersen ME, Meek ME, Reiter LW, Lambert JC, Clewell HJ 3rd, Stephens ML, Zhao QJ, Wesselkamper SC, Flowers L, Carney EW, Pastoor TP, Petersen DD, Yauk CL, Nong A. Thomas RS, et al. Among authors: meek me. Toxicol Sci. 2013 Nov;136(1):4-18. doi: 10.1093/toxsci/kft178. Epub 2013 Aug 19. Toxicol Sci. 2013. PMID: 23958734 Free PMC article.

2

A framework for human relevance analysis of information on carcinogenic modes of action.

Meek ME, Bucher JR, Cohen SM, Dellarco V, Hill RN, Lehman-McKeeman LD, Longfellow DG, Pastoor T, Seed J, Patton DE. Meek ME, et al. Crit Rev Toxicol. 2003;33(6):591-653. doi: 10.1080/713608373. Crit Rev Toxicol. 2003. PMID: 14727733 Review.

3

Incorporation of pharmacokinetic and pharmacodynamic data into risk assessments.

Lipscomb JC, Meek ME, Krishnan K, Kedderis GL, Clewell H, Haber L. Lipscomb JC, et al. Among authors: meek me. Toxicol Mech Methods. 2004;14(3):145-58. doi: 10.1080/15376520490429382. Toxicol Mech Methods. 2004. PMID: 20021141

4

Application of benchmark dose modeling to protein expression data in the development and analysis of mode of action/adverse outcome pathways for testicular toxicity.

Chepelev NL, Meek ME, Yauk CL. Chepelev NL, et al. Among authors: meek me. J Appl Toxicol. 2014 Nov;34(11):1115-21. doi: 10.1002/jat.3071. Epub 2014 Sep 22. J Appl Toxicol. 2014. PMID: 25244189 Review.

5

Gaining acceptance for the use of in vitro toxicity assays and QIVIVE in regulatory risk assessment.

Meek ME, Lipscomb JC. Meek ME, et al. Toxicology. 2015 Jun 5;332:112-23. doi: 10.1016/j.tox.2015.01.010. Epub 2015 Jan 15. Toxicology. 2015. PMID: 25598226 Review.

6

Development of the adverse outcome pathway "alkylation of DNA in male premeiotic germ cells leading to heritable mutations" using the OECD's users' handbook supplement.

Yauk CL, Lambert IB, Meek ME, Douglas GR, Marchetti F. Yauk CL, et al. Among authors: meek me. Environ Mol Mutagen. 2015 Dec;56(9):724-50. doi: 10.1002/em.21954. Epub 2015 May 22. Environ Mol Mutagen. 2015. PMID: 26010389

7

How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology.

Wittwehr C, Aladjov H, Ankley G, Byrne HJ, de Knecht J, Heinzle E, Klambauer G, Landesmann B, Luijten M, MacKay C, Maxwell G, Meek ME, Paini A, Perkins E, Sobanski T, Villeneuve D, Waters KM, Whelan M. Wittwehr C, et al. Among authors: meek me. Toxicol Sci. 2017 Feb;155(2):326-336. doi: 10.1093/toxsci/kfw207. Epub 2016 Dec 19. Toxicol Sci. 2017. PMID: 27994170 Free PMC article.

8

The need for good practice in the application of mechanistic constructs in hazard and risk assessment.

Meek MEB, Wikoff D. Meek MEB, et al. Toxicol Sci. 2023 Jun 28;194(1):13-22. doi: 10.1093/toxsci/kfad039. Toxicol Sci. 2023. PMID: 37074944

9

Biologically motivated computational modeling: contribution to risk assessment.

Meek ME. Meek ME. Toxicol Sci. 2004 Nov;82(1):1-2. doi: 10.1093/toxsci/kfh282. Toxicol Sci. 2004. PMID: 15540279 No abstract available.

10

Framework for human health risk assessment of non-cancer effects resulting from short-duration and intermittent exposures to chemicals.

Haber LT, Sandhu R, Li-Muller A, Mohapatra A, Petrovic S, Meek ME. Haber LT, et al. Among authors: meek me. J Appl Toxicol. 2016 Sep;36(9):1077-89. doi: 10.1002/jat.3345. Epub 2016 Jun 14. J Appl Toxicol. 2016. PMID: 27297613

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