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Inflammatory mediators reduce surface PrPc on human BMVEC resulting in decreased barrier integrity.
Lab Invest. 2018 Oct;98(10):1347-1359. doi: 10.1038/s41374-018-0090-z. Epub 2018 Jun 29.
Lab Invest. 2018.
PMID: 29959417
Free PMC article.
The Role of Shed PrPc in the Neuropathogenesis of HIV Infection.
Megra BW, Eugenin EA, Berman JW.
Megra BW, et al.
J Immunol. 2017 Jul 1;199(1):224-232. doi: 10.4049/jimmunol.1601041. Epub 2017 May 22.
J Immunol. 2017.
PMID: 28533442
Free PMC article.
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Protease resistant protein cellular isoform (PrP(c)) as a biomarker: clues into the pathogenesis of HAND.
Megra B, Eugenin E, Roberts T, Morgello S, Berman JW.
Megra B, et al.
J Neuroimmune Pharmacol. 2013 Dec;8(5):1159-66. doi: 10.1007/s11481-013-9458-4. Epub 2013 Apr 25.
J Neuroimmune Pharmacol. 2013.
PMID: 23616272
Free PMC article.
Review.
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Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.
Dickens AM, Tovar-Y-Romo LB, Yoo SW, Trout AL, Bae M, Kanmogne M, Megra B, Williams DW, Witwer KW, Gacias M, Tabatadze N, Cole RN, Casaccia P, Berman JW, Anthony DC, Haughey NJ.
Dickens AM, et al.
Sci Signal. 2017 Apr 4;10(473):eaai7696. doi: 10.1126/scisignal.aai7696.
Sci Signal. 2017.
PMID: 28377412
Free PMC article.
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