Meini S - Search Results

1

Monocyclic human tachykinin NK-2 receptor antagonists as evolution of a potent bicyclic antagonist: QSAR and site-directed mutagenesis studies.

Giolitti A, Altamura M, Bellucci F, Giannotti D, Meini S, Patacchini R, Rotondaro L, Zappitelli S, Maggi CA. Giolitti A, et al. Among authors: meini s. J Med Chem. 2002 Aug 1;45(16):3418-29. doi: 10.1021/jm011127h. J Med Chem. 2002. PMID: 12139452

2

Interaction of linear and cyclic peptide antagonists at the human B(2) kinin receptor.

Cucchi P, Meini S, Quartara L, Giolitti A, Zappitelli S, Rotondaro L, Maggi CA. Cucchi P, et al. Among authors: meini s. Peptides. 2002 Aug;23(8):1457-63. doi: 10.1016/s0196-9781(02)00081-5. Peptides. 2002. PMID: 12182947

3

Site-directed mutagenesis at the human B2 receptor and molecular modelling to define the pharmacophore of non-peptide bradykinin receptor antagonists.

Meini S, Cucchi P, Bellucci F, Catalani C, Faiella A, Rotondaro L, Quartara L, Giolitti A, Maggi CA. Meini S, et al. Biochem Pharmacol. 2004 Feb 15;67(4):601-9. doi: 10.1016/j.bcp.2003.09.034. Biochem Pharmacol. 2004. PMID: 14757160

4

Mutagenesis at the human tachykinin NK(2) receptor to define the binding site of a novel class of antagonists.

Meini S, Bellucci F, Catalani C, Cucchi P, Patacchini R, Rotondaro L, Altamura M, Giuliani S, Giolitti A, Maggi CA. Meini S, et al. Eur J Pharmacol. 2004 Mar 19;488(1-3):61-9. doi: 10.1016/j.ejphar.2004.02.016. Eur J Pharmacol. 2004. PMID: 15044036

5

Pharmacological evaluation of alpha and beta human tachykinin NK(2) receptor splice variants expressed in CHO cells.

Bellucci F, Meini S, Catalioto RM, Catalani C, Giuliani S, Quartara L, Giolitti A, Faiella A, Rotondaro L, Candenas ML, Pinto FM, Maggi CA. Bellucci F, et al. Among authors: meini s. Eur J Pharmacol. 2004 Sep 24;499(3):229-38. doi: 10.1016/j.ejphar.2004.07.075. Eur J Pharmacol. 2004. PMID: 15381044

6

Pharmacology of an original and selective nonpeptide antagonist ligand for the human tachykinin NK2 receptor.

Meini S, Catalani C, Bellucci F, Cucchi P, Giuliani S, Zappitelli S, Rotondaro L, Pasqui F, Guidi A, Altamura M, Giolitti A, Maggi CA. Meini S, et al. Eur J Pharmacol. 2005 Jun 1;516(2):104-11. doi: 10.1016/j.ejphar.2005.04.033. Eur J Pharmacol. 2005. PMID: 15925360

7

Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides.

Fattori D, Rossi C, Fincham CI, Berettoni M, Calvani F, Catrambone F, Felicetti P, Gensini M, Terracciano R, Altamura M, Bressan A, Giuliani S, Maggi CA, Meini S, Valenti C, Quartara L. Fattori D, et al. Among authors: meini s. J Med Chem. 2006 Jun 15;49(12):3602-13. doi: 10.1021/jm060137l. J Med Chem. 2006. PMID: 16759102

8

Discovery of a new series of potent and selective linear tachykinin NK2 receptor antagonists.

Fedi V, Altamura M, Catalioto RM, Giannotti D, Giolitti A, Giuliani S, Guidi A, Harmat NJ, Lecci A, Meini S, Nannicini R, Pasqui F, Tramontana M, Triolo A, Maggi CA. Fedi V, et al. Among authors: meini s. J Med Chem. 2007 Oct 4;50(20):4793-807. doi: 10.1021/jm070289w. Epub 2007 Sep 12. J Med Chem. 2007. PMID: 17850056

9

Modulation on C- and N-terminal moieties of a series of potent and selective linear tachykinin NK(2) receptor antagonists.

Gensini M, Altamura M, Dimoulas T, Fedi V, Giannotti D, Giuliani S, Guidi A, Harmat NJ, Meini S, Nannicini R, Pasqui F, Tramontana M, Triolo A, Maggi CA. Gensini M, et al. Among authors: meini s. ChemMedChem. 2010 Jan;5(1):65-78. doi: 10.1002/cmdc.200900389. ChemMedChem. 2010. PMID: 19957262

10

Structure-activity relationships of 6-methyl-benzo[b]thiophene-2-carboxylic acid (1-[(S)-1-benzyl-4-[4-(tetrahydropyran-4-ylmethyl)piperazin-1-yl]butylcarbamoyl]cyclopentyl)amide, potent antagonist of the neurokinin-2 receptor.

Fattori D, Porcelloni M, D'Andrea P, Catalioto RM, Ettorre A, Giuliani S, Marastoni E, Mauro S, Meini S, Rossi C, Altamura M, Maggi CA. Fattori D, et al. Among authors: meini s. J Med Chem. 2010 May 27;53(10):4148-65. doi: 10.1021/jm100176s. J Med Chem. 2010. PMID: 20408549

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