Melissa Vargo - Search Results

Year	Number of Results
2004	2
2006	2
2007	2
2008	2
2009	3
2010	1
2013	2
2024	0

1

Arsenic trioxide and ascorbic acid demonstrate promising activity against primary human CLL cells in vitro.

Biswas S, Zhao X, Mone AP, Mo X, Vargo M, Jarjoura D, Byrd JC, Muthusamy N. Biswas S, et al. Among authors: vargo m. Leuk Res. 2010 Jul;34(7):925-31. doi: 10.1016/j.leukres.2010.01.020. Epub 2010 Feb 19. Leuk Res. 2010. PMID: 20171736 Free PMC article.

2

First three-dimensional structure of Toxoplasma gondii thymidylate synthase-dihydrofolate reductase: insights for catalysis, interdomain interactions, and substrate channeling.

Sharma H, Landau MJ, Vargo MA, Spasov KA, Anderson KS. Sharma H, et al. Among authors: vargo ma. Biochemistry. 2013 Oct 15;52(41):7305-7317. doi: 10.1021/bi400576t. Epub 2013 Oct 3. Biochemistry. 2013. PMID: 24053355 Free PMC article.

3

Disruption of the crossover helix impairs dihydrofolate reductase activity in the bifunctional enzyme TS-DHFR from Cryptosporidium hominis.

Vargo MA, Martucci WE, Anderson KS. Vargo MA, et al. Biochem J. 2009 Feb 1;417(3):757-64. doi: 10.1042/BJ20081247. Biochem J. 2009. PMID: 18851711 Free PMC article.

4

Heterodimers of wild-type and subunit interface mutant enzymes of glutathione S-transferase A1-1: interactive or independent active sites?

Vargo MA, Colman RF. Vargo MA, et al. Protein Sci. 2004 Jun;13(6):1586-93. doi: 10.1110/ps.04694004. Protein Sci. 2004. PMID: 15152091 Free PMC article.

5

The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo.

Lucas DM, Edwards RB, Lozanski G, West DA, Shin JD, Vargo MA, Davis ME, Rozewski DM, Johnson AJ, Su BN, Goettl VM, Heerema NA, Lin TS, Lehman A, Zhang X, Jarjoura D, Newman DJ, Byrd JC, Kinghorn AD, Grever MR. Lucas DM, et al. Among authors: vargo ma. Blood. 2009 May 7;113(19):4656-66. doi: 10.1182/blood-2008-09-175430. Epub 2009 Feb 3. Blood. 2009. PMID: 19190247 Free PMC article.

6

Novel non-active site inhibitor of Cryptosporidium hominis TS-DHFR identified by a virtual screen.

Martucci WE, Udier-Blagovic M, Atreya C, Babatunde O, Vargo MA, Jorgensen WL, Anderson KS. Martucci WE, et al. Among authors: vargo ma. Bioorg Med Chem Lett. 2009 Jan 15;19(2):418-23. doi: 10.1016/j.bmcl.2008.11.054. Epub 2008 Nov 20. Bioorg Med Chem Lett. 2009. PMID: 19059777 Free PMC article.

7

Subunit interface residues of glutathione S-transferase A1-1 that are important in the monomer-dimer equilibrium.

Vargo MA, Nguyen L, Colman RF. Vargo MA, et al. Biochemistry. 2004 Mar 30;43(12):3327-35. doi: 10.1021/bi030245z. Biochemistry. 2004. PMID: 15035604

8

Apigenin-induced-apoptosis is mediated by the activation of PKCdelta and caspases in leukemia cells.

Vargo MA, Voss OH, Poustka F, Cardounel AJ, Grotewold E, Doseff AI. Vargo MA, et al. Biochem Pharmacol. 2006 Sep 14;72(6):681-92. doi: 10.1016/j.bcp.2006.06.010. Epub 2006 Jul 17. Biochem Pharmacol. 2006. PMID: 16844095

9

Explaining an unusually fast parasitic enzyme: folate tail-binding residues dictate substrate positioning and catalysis in Cryptosporidium hominis thymidylate synthase.

Martucci WE, Vargo MA, Anderson KS. Martucci WE, et al. Among authors: vargo ma. Biochemistry. 2008 Aug 26;47(34):8902-11. doi: 10.1021/bi800466z. Epub 2008 Aug 2. Biochemistry. 2008. PMID: 18672899 Free PMC article.

10

Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.

Nicholas C, Batra S, Vargo MA, Voss OH, Gavrilin MA, Wewers MD, Guttridge DC, Grotewold E, Doseff AI. Nicholas C, et al. Among authors: vargo ma. J Immunol. 2007 Nov 15;179(10):7121-7. doi: 10.4049/jimmunol.179.10.7121. J Immunol. 2007. PMID: 17982104

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