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Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR.
Ross DM, Branford S, Seymour JF, Schwarer AP, Arthur C, Bartley PA, Slader C, Field C, Dang P, Filshie RJ, Mills AK, Grigg AP, Melo JV, Hughes TP. Ross DM, et al. Among authors: melo jv. Leukemia. 2010 Oct;24(10):1719-24. doi: 10.1038/leu.2010.185. Epub 2010 Sep 2. Leukemia. 2010. PMID: 20811403
Chronic myeloid leukemia.
Melo JV, Hughes TP, Apperley JF. Melo JV, et al. Hematology Am Soc Hematol Educ Program. 2003:132-52. doi: 10.1182/asheducation-2003.1.132. Hematology Am Soc Hematol Educ Program. 2003. PMID: 14633780 Free article. Review.
Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study.
Ross DM, Branford S, Seymour JF, Schwarer AP, Arthur C, Yeung DT, Dang P, Goyne JM, Slader C, Filshie RJ, Mills AK, Melo JV, White DL, Grigg AP, Hughes TP. Ross DM, et al. Among authors: melo jv. Blood. 2013 Jul 25;122(4):515-22. doi: 10.1182/blood-2013-02-483750. Epub 2013 May 23. Blood. 2013. PMID: 23704092 Free article. Clinical Trial.
Do we have to kill the last CML cell?
Ross DM, Hughes TP, Melo JV. Ross DM, et al. Among authors: melo jv. Leukemia. 2011 Feb;25(2):193-200. doi: 10.1038/leu.2010.197. Epub 2010 Sep 16. Leukemia. 2011. PMID: 20844563 Review.
227 results