Meloche S - Search Results

1

An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme.

Ceccarelli DF, Tang X, Pelletier B, Orlicky S, Xie W, Plantevin V, Neculai D, Chou YC, Ogunjimi A, Al-Hakim A, Varelas X, Koszela J, Wasney GA, Vedadi M, Dhe-Paganon S, Cox S, Xu S, Lopez-Girona A, Mercurio F, Wrana J, Durocher D, Meloche S, Webb DR, Tyers M, Sicheri F. Ceccarelli DF, et al. Among authors: meloche s. Cell. 2011 Jun 24;145(7):1075-87. doi: 10.1016/j.cell.2011.05.039. Epub 2011 Jun 16. Cell. 2011. PMID: 21683433 Free article.

2

Development of a high-throughput assay to identify inhibitors of the ubiquitin-conjugating enzyme UBCH10.

Cléroux P, Voisin L, Meloche S. Cléroux P, et al. Among authors: meloche s. SLAS Discov. 2022 Jun;27(4):266-271. doi: 10.1016/j.slasd.2022.03.007. Epub 2022 Mar 25. SLAS Discov. 2022. PMID: 35342035 Free article.

3

Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen.

Pelletier B, Duhamel S, Tambutet G, Jarvis S, Cléroux P, David M, Tanguay PL, Voisin L, James C, Lavoie R, Gareau Y, Flynn-Robitaille J, Lorca T, Ruel R, Marinier A, Meloche S. Pelletier B, et al. Among authors: meloche s. ACS Chem Biol. 2023 May 19;18(5):1039-1046. doi: 10.1021/acschembio.2c00909. Epub 2023 Apr 25. ACS Chem Biol. 2023. PMID: 37097827

4

Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site.

Fleury S, Lamarre D, Meloche S, Ryu SE, Cantin C, Hendrickson WA, Sekaly RP. Fleury S, et al. Among authors: meloche s. Cell. 1991 Sep 6;66(5):1037-49. doi: 10.1016/0092-8674(91)90447-7. Cell. 1991. PMID: 1889086

5

p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2.

Rodier G, Makris C, Coulombe P, Scime A, Nakayama K, Nakayama KI, Meloche S. Rodier G, et al. Among authors: meloche s. J Cell Biol. 2005 Jan 3;168(1):55-66. doi: 10.1083/jcb.200404146. J Cell Biol. 2005. PMID: 15631990 Free PMC article.

6

Phosphorylation of Ser72 does not regulate the ubiquitin ligase activity and subcellular localization of Skp2.

Boutonnet C, Tanguay PL, Julien C, Rodier G, Coulombe P, Meloche S. Boutonnet C, et al. Among authors: meloche s. Cell Cycle. 2010 Mar 1;9(5):975-9. doi: 10.4161/cc.9.5.10915. Epub 2010 Mar 9. Cell Cycle. 2010. PMID: 20160482

7

E4F1 is a master regulator of CHK1-mediated functions.

Grote D, Moison C, Duhamel S, Chagraoui J, Girard S, Yang J, Mayotte N, Coulombe Y, Masson JY, Brown GW, Meloche S, Sauvageau G. Grote D, et al. Among authors: meloche s. Cell Rep. 2015 Apr 14;11(2):210-9. doi: 10.1016/j.celrep.2015.03.019. Epub 2015 Apr 2. Cell Rep. 2015. PMID: 25843717 Free article.

8

Phosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phase.

Rodier G, Coulombe P, Tanguay PL, Boutonnet C, Meloche S. Rodier G, et al. Among authors: meloche s. EMBO J. 2008 Feb 20;27(4):679-91. doi: 10.1038/emboj.2008.6. Epub 2008 Jan 31. EMBO J. 2008. PMID: 18239684 Free PMC article.

9

Functional Redundancy of ERK1 and ERK2 MAP Kinases during Development.

Frémin C, Saba-El-Leil MK, Lévesque K, Ang SL, Meloche S. Frémin C, et al. Among authors: meloche s. Cell Rep. 2015 Aug 11;12(6):913-21. doi: 10.1016/j.celrep.2015.07.011. Epub 2015 Jul 30. Cell Rep. 2015. PMID: 26235619 Free article.

10

The IKK-related kinases: from innate immunity to oncogenesis.

Clément JF, Meloche S, Servant MJ. Clément JF, et al. Among authors: meloche s. Cell Res. 2008 Sep;18(9):889-99. doi: 10.1038/cr.2008.273. Cell Res. 2008. PMID: 19160540 Review.

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