Mendonça L - Search Results

1

Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.

Nóbrega C, Carmo-Silva S, Albuquerque D, Vasconcelos-Ferreira A, Vijayakumar UG, Mendonça L, Hirai H, de Almeida LP. Nóbrega C, et al. Among authors: mendonca l. Brain. 2015 Dec;138(Pt 12):3537-54. doi: 10.1093/brain/awv298. Epub 2015 Oct 21. Brain. 2015. PMID: 26490332

2

Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice.

Mendonça LS, Nóbrega C, Hirai H, Kaspar BK, Pereira de Almeida L. Mendonça LS, et al. Brain. 2015 Feb;138(Pt 2):320-35. doi: 10.1093/brain/awu352. Epub 2014 Dec 19. Brain. 2015. PMID: 25527827

3

Intravenous administration of brain-targeted stable nucleic acid lipid particles alleviates Machado-Joseph disease neurological phenotype.

Conceição M, Mendonça L, Nóbrega C, Gomes C, Costa P, Hirai H, Moreira JN, Lima MC, Manjunath N, Pereira de Almeida L. Conceição M, et al. Among authors: mendonca l. Biomaterials. 2016 Mar;82:124-37. doi: 10.1016/j.biomaterials.2015.12.021. Epub 2015 Dec 21. Biomaterials. 2016. PMID: 26757259

4

Safety profile of the intravenous administration of brain-targeted stable nucleic acid lipid particles.

Conceição M, Mendonça L, Nóbrega C, Gomes C, Costa P, Hirai H, Moreira JN, Lima MC, Manjunath N, de Almeida LP. Conceição M, et al. Among authors: mendonca l. Data Brief. 2016 Jan 20;6:700-5. doi: 10.1016/j.dib.2016.01.017. eCollection 2016 Mar. Data Brief. 2016. PMID: 26958628 Free PMC article.

5

Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review.

Alves-Cruzeiro JM, Mendonça L, Pereira de Almeida L, Nóbrega C. Alves-Cruzeiro JM, et al. Among authors: mendonca l. Front Neurosci. 2016 Dec 15;10:572. doi: 10.3389/fnins.2016.00572. eCollection 2016. Front Neurosci. 2016. PMID: 28018166 Free PMC article. Review.

6

Stem Cell-Based Therapies for Polyglutamine Diseases.

Mendonça LS, Onofre I, Miranda CO, Perfeito R, Nóbrega C, de Almeida LP. Mendonça LS, et al. Adv Exp Med Biol. 2018;1049:439-466. doi: 10.1007/978-3-319-71779-1_21. Adv Exp Med Biol. 2018. PMID: 29427116 Review.

7

Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado-Joseph disease models.

Marcelo A, Brito F, Carmo-Silva S, Matos CA, Alves-Cruzeiro J, Vasconcelos-Ferreira A, Koppenol R, Mendonça L, de Almeida LP, Nóbrega C. Marcelo A, et al. Among authors: mendonca l. Hum Mol Genet. 2019 Jan 1;28(1):51-63. doi: 10.1093/hmg/ddy328. Hum Mol Genet. 2019. PMID: 30219871

8

RNA Interference Therapy for Machado-Joseph Disease: Long-Term Safety Profile of Lentiviral Vectors Encoding Short Hairpin RNAs Targeting Mutant Ataxin-3.

Nóbrega C, Codêsso JM, Mendonça L, Pereira de Almeida L. Nóbrega C, et al. Among authors: mendonca l. Hum Gene Ther. 2019 Jul;30(7):841-854. doi: 10.1089/hum.2018.157. Epub 2019 May 28. Hum Gene Ther. 2019. PMID: 30760052

9

Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado-Joseph disease models.

Mendonça LS, Nóbrega C, Tavino S, Brinkhaus M, Matos C, Tomé S, Moreira R, Henriques D, Kaspar BK, Pereira de Almeida L. Mendonça LS, et al. Hum Mol Genet. 2019 Nov 15;28(22):3691-3703. doi: 10.1093/hmg/ddz097. Hum Mol Genet. 2019. PMID: 31127937

10

Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia.

Nóbrega C, Mendonça L, Marcelo A, Lamazière A, Tomé S, Despres G, Matos CA, Mechmet F, Langui D, den Dunnen W, de Almeida LP, Cartier N, Alves S. Nóbrega C, et al. Among authors: mendonca l. Acta Neuropathol. 2019 Nov;138(5):837-858. doi: 10.1007/s00401-019-02019-7. Epub 2019 Jun 14. Acta Neuropathol. 2019. PMID: 31197505

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