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Safety and immunogenicity of a mosquito saliva peptide-based vaccine: a randomised, placebo-controlled, double-blind, phase 1 trial.
Manning JE, Oliveira F, Coutinho-Abreu IV, Herbert S, Meneses C, Kamhawi S, Baus HA, Han A, Czajkowski L, Rosas LA, Cervantes-Medina A, Athota R, Reed S, Mateja A, Hunsberger S, James E, Pleguezuelos O, Stoloff G, Valenzuela JG, Memoli MJ. Manning JE, et al. Among authors: meneses c. Lancet. 2020 Jun 27;395(10242):1998-2007. doi: 10.1016/S0140-6736(20)31048-5. Epub 2020 Jun 11. Lancet. 2020. PMID: 32534628 Free PMC article. Clinical Trial.
KSAC, a defined Leishmania antigen, plus adjuvant protects against the virulence of L. major transmitted by its natural vector Phlebotomus duboscqi.
Gomes R, Teixeira C, Oliveira F, Lawyer PG, Elnaiem DE, Meneses C, Goto Y, Bhatia A, Howard RF, Reed SG, Valenzuela JG, Kamhawi S. Gomes R, et al. Among authors: meneses c. PLoS Negl Trop Dis. 2012;6(4):e1610. doi: 10.1371/journal.pntd.0001610. Epub 2012 Apr 3. PLoS Negl Trop Dis. 2012. PMID: 22509423 Free PMC article.
Delayed-type hypersensitivity to sand fly saliva in humans from a leishmaniasis-endemic area of Mali is Th1-mediated and persists to midlife.
Oliveira F, Traoré B, Gomes R, Faye O, Gilmore DC, Keita S, Traoré P, Teixeira C, Coulibaly CA, Samake S, Meneses C, Sissoko I, Fairhurst RM, Fay MP, Anderson JM, Doumbia S, Kamhawi S, Valenzuela JG. Oliveira F, et al. Among authors: meneses c. J Invest Dermatol. 2013 Feb;133(2):452-9. doi: 10.1038/jid.2012.315. Epub 2012 Sep 20. J Invest Dermatol. 2013. PMID: 22992802 Free PMC article.
Enhanced protective efficacy of nonpathogenic recombinant leishmania tarentolae expressing cysteine proteinases combined with a sand fly salivary antigen.
Zahedifard F, Gholami E, Taheri T, Taslimi Y, Doustdari F, Seyed N, Torkashvand F, Meneses C, Papadopoulou B, Kamhawi S, Valenzuela JG, Rafati S. Zahedifard F, et al. Among authors: meneses c. PLoS Negl Trop Dis. 2014 Mar 27;8(3):e2751. doi: 10.1371/journal.pntd.0002751. eCollection 2014 Mar. PLoS Negl Trop Dis. 2014. PMID: 24675711 Free PMC article.
A Listeria monocytogenes-based vaccine that secretes sand fly salivary protein LJM11 confers long-term protection against vector-transmitted Leishmania major.
Abi Abdallah DS, Pavinski Bitar A, Oliveira F, Meneses C, Park JJ, Mendez S, Kamhawi S, Valenzuela JG, Marquis H. Abi Abdallah DS, et al. Among authors: meneses c. Infect Immun. 2014 Jul;82(7):2736-45. doi: 10.1128/IAI.01633-14. Epub 2014 Apr 14. Infect Immun. 2014. PMID: 24733091 Free PMC article.
Characterization of the early inflammatory infiltrate at the feeding site of infected sand flies in mice protected from vector-transmitted Leishmania major by exposure to uninfected bites.
Teixeira C, Gomes R, Oliveira F, Meneses C, Gilmore DC, Elnaiem DE, Valenzuela JG, Kamhawi S. Teixeira C, et al. Among authors: meneses c. PLoS Negl Trop Dis. 2014 Apr 24;8(4):e2781. doi: 10.1371/journal.pntd.0002781. eCollection 2014 Apr. PLoS Negl Trop Dis. 2014. PMID: 24762408 Free PMC article.
A sand fly salivary protein vaccine shows efficacy against vector-transmitted cutaneous leishmaniasis in nonhuman primates.
Oliveira F, Rowton E, Aslan H, Gomes R, Castrovinci PA, Alvarenga PH, Abdeladhim M, Teixeira C, Meneses C, Kleeman LT, Guimarães-Costa AB, Rowland TE, Gilmore D, Doumbia S, Reed SG, Lawyer PG, Andersen JF, Kamhawi S, Valenzuela JG. Oliveira F, et al. Among authors: meneses c. Sci Transl Med. 2015 Jun 3;7(290):290ra90. doi: 10.1126/scitranslmed.aaa3043. Sci Transl Med. 2015. PMID: 26041707
239 results