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An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
Chen M, Zhang J, Sampieri K, Clohessy JG, Mendez L, Gonzalez-Billalabeitia E, Liu XS, Lee YR, Fung J, Katon JM, Menon AV, Webster KA, Ng C, Palumbieri MD, Diolombi MS, Breitkopf SB, Teruya-Feldstein J, Signoretti S, Bronson RT, Asara JM, Castillo-Martin M, Cordon-Cardo C, Pandolfi PP. Chen M, et al. Among authors: menon av. Nat Genet. 2018 Feb;50(2):206-218. doi: 10.1038/s41588-017-0027-2. Epub 2018 Jan 15. Nat Genet. 2018. PMID: 29335545 Free PMC article.
PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.
Zhang J, Lee YR, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. Zhang J, et al. Among authors: menon av. Cancer Discov. 2019 Sep;9(9):1306-1323. doi: 10.1158/2159-8290.CD-18-0083. Epub 2019 Jun 19. Cancer Discov. 2019. PMID: 31217297 Free PMC article.
Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy.
Mugoni V, Panella R, Cheloni G, Chen M, Pozdnyakova O, Stroopinsky D, Guarnerio J, Monteleone E, Lee JD, Mendez L, Menon AV, Aster JC, Lane AA, Stone RM, Galinsky I, Zamora JC, Lo-Coco F, Bhasin MK, Avigan D, Longo L, Clohessy JG, Pandolfi PP. Mugoni V, et al. Among authors: menon av. Cell Res. 2019 Jun;29(6):446-459. doi: 10.1038/s41422-019-0162-7. Epub 2019 Apr 25. Cell Res. 2019. PMID: 31024166 Free PMC article.
Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals.
Grillo AS, SantaMaria AM, Kafina MD, Cioffi AG, Huston NC, Han M, Seo YA, Yien YY, Nardone C, Menon AV, Fan J, Svoboda DC, Anderson JB, Hong JD, Nicolau BG, Subedi K, Gewirth AA, Wessling-Resnick M, Kim J, Paw BH, Burke MD. Grillo AS, et al. Among authors: menon av. Science. 2017 May 12;356(6338):608-616. doi: 10.1126/science.aah3862. Science. 2017. PMID: 28495746 Free PMC article.
22 results